NURS 5334 PHARM FINAL EXAM 2024-2025 LATEST REAL EXAM
WITH DETAILED QUESTIONS AND CORRECT ANSWERS
(VERIFIED ANSWERS ALREADY GRADED A+
Which statements about vancomycin is accurate? Check all that apply.
•A. Active against methicillin-resistant staphylococci
•B. Bacteriostatic
•C. Causes Red Man Syndrome
•D. Prevents RNA replication
•E. Inhibits beta lactamase
•A. Active against methicillin-resistant staphylococci
•C. Causes Red Man Syndrome
The mechanism of action of the tetracyclines involves
Inhibiting protein synthesis
Regarding the mechanism of action of aminoglycosides, the drugs:
Cause misreading of the code on the RNA template to inhibit protein synthesis
Which statement is accurate regarding the antibacterial action of gentamicin?
•A. Antibacterial activity is often reduced by the presence of an inhibitor of cell wall
synthesis
•B. Antibacterial action is not concentration-dependent
•C. Antibacterial action is time dependent
•D. Gentamicin continues to exert antibacterial effects even after plasma levels decrease
below detectable levels
D. Gentamicin continues to exert antibacterial effects even after plasma levels decrease
below detectable levels
,If a patient was treated with the macrolide erythromycin, he/she should:
•A. Avoid exposure to sunlight
•B. Avoid taking supplementary iron tablets
•C. Temporarily stop simvastatin while taking erythromycin
•D. Have renal function checked before treatment
•C. Temporarily stop simvastatin while taking erythromycin
A 24 year old woman has returned from a vacation abroad suffering from traveler's
diarrhea, and her problem has not responded to antidiarrheal drugs. A pathogenic gram-
negative bacillus is suspected. Which drug is most likely to be effective in the treatment of
this patient?
Ciprofloxacin
Which of the following statements about fluoroquinolones is accurate?
•A. Fluoroquinolone is drug of choice for 7 year old with UTI
•B. Antacids increase the bioavailability of fluoroquinolones
•C. Fluoroquinolones have different therapeutic applications depending on the generation
•D. Fluoroquinolones are contraindicated in patients with hepatic dysfunction
C. Fluoroquinolones have different therapeutic applications depending on the generation
Which adverse effect is MOST LIKELY to occur with sulfonamides?
Skin reactions
Which statement about ciprofloxacin is accurate?
•A. It is active against most MRSA strains
•B. During treatment, tendonitis and even tendon rupture may occur
•C. Most "first time" urinary tract infections are resistant to ciprofloxacin
•D. Organisms associated wit CAP are highly active to ciprofloxacin
•B. During treatment, tendonitis and even tendon rupture may occur
,The primary reason for the use of drug combinations in the treatment of TB is to:
Delay or prevent the emergence of resistance
Which statement about fluconazole is accurate?
•A. Does not penetrate the blood-brain barrier
•B. Is safe during pregnancy
•C. Primary route of elimination is renal
•D. Is only used topically
C. Primary route of elimination is renal
You have received the culture and sensitivity report from the lab. Your patient's urine is
growing E coli and the following is reported:
•Ampicillin Minimum Inhibitory Concentration (MIC) 38 mg/L
•Gentamicin MIC 20 mg/L
•Piperacillin MIC 4 mg/L
•Ciprofloxacin MIC 2.5 mg/L
Which of the following would you choose to treat the UTI?
Ciprofloxacin
A 55 year old man who has been on anticoagulant treatment for many years is diagnosed
with TB. Which of the following antimycobacterial agents would most likely induce
cytochrome P450 enzymes in the patient's liver thereby modify the effects of his
anticoagulant treatment?
Rifampin
Which drug is an antiviral that can be used to treat herpes simplex virus?
•A. Zanamivir
•B. Acyclovir
•C. Amphotericin B
•D. Ethambutol
, B. Acyclovir (others: valacyclovir, famciclovir)
Which of the following describes the mechanism of action of oseltamivir?
•A. selectively inhibits neuraminidase
•B. Therapeutic spectrum is limited to influenza A infections
•C. Inhibits protease
•D. It is not well understood
A. selectively inhibits neuraminidase
First generation Cephalosporins are best against which of the following organisms?
•A. Gram negative rods
•B. Gram positive cocci
•C. Fungi
•D. Anaerobes
B. Gram positive cocci
Isoniazid can cause serious adverse effects including:
neuropathy
Seizures Hepatitis
Peripheral
Cefepime is eliminated via
Tubular secretion and/or glomerular filtration
Which of the following is a common adverse effect of trimethoprim/ sulfamethoxazole
(TMP/SMZ)?
•A. Decreased prothrombin times in patients receiving warfarin
•B. Skin reactions
•C. Tendon rupture
•D. Constipation
WITH DETAILED QUESTIONS AND CORRECT ANSWERS
(VERIFIED ANSWERS ALREADY GRADED A+
Which statements about vancomycin is accurate? Check all that apply.
•A. Active against methicillin-resistant staphylococci
•B. Bacteriostatic
•C. Causes Red Man Syndrome
•D. Prevents RNA replication
•E. Inhibits beta lactamase
•A. Active against methicillin-resistant staphylococci
•C. Causes Red Man Syndrome
The mechanism of action of the tetracyclines involves
Inhibiting protein synthesis
Regarding the mechanism of action of aminoglycosides, the drugs:
Cause misreading of the code on the RNA template to inhibit protein synthesis
Which statement is accurate regarding the antibacterial action of gentamicin?
•A. Antibacterial activity is often reduced by the presence of an inhibitor of cell wall
synthesis
•B. Antibacterial action is not concentration-dependent
•C. Antibacterial action is time dependent
•D. Gentamicin continues to exert antibacterial effects even after plasma levels decrease
below detectable levels
D. Gentamicin continues to exert antibacterial effects even after plasma levels decrease
below detectable levels
,If a patient was treated with the macrolide erythromycin, he/she should:
•A. Avoid exposure to sunlight
•B. Avoid taking supplementary iron tablets
•C. Temporarily stop simvastatin while taking erythromycin
•D. Have renal function checked before treatment
•C. Temporarily stop simvastatin while taking erythromycin
A 24 year old woman has returned from a vacation abroad suffering from traveler's
diarrhea, and her problem has not responded to antidiarrheal drugs. A pathogenic gram-
negative bacillus is suspected. Which drug is most likely to be effective in the treatment of
this patient?
Ciprofloxacin
Which of the following statements about fluoroquinolones is accurate?
•A. Fluoroquinolone is drug of choice for 7 year old with UTI
•B. Antacids increase the bioavailability of fluoroquinolones
•C. Fluoroquinolones have different therapeutic applications depending on the generation
•D. Fluoroquinolones are contraindicated in patients with hepatic dysfunction
C. Fluoroquinolones have different therapeutic applications depending on the generation
Which adverse effect is MOST LIKELY to occur with sulfonamides?
Skin reactions
Which statement about ciprofloxacin is accurate?
•A. It is active against most MRSA strains
•B. During treatment, tendonitis and even tendon rupture may occur
•C. Most "first time" urinary tract infections are resistant to ciprofloxacin
•D. Organisms associated wit CAP are highly active to ciprofloxacin
•B. During treatment, tendonitis and even tendon rupture may occur
,The primary reason for the use of drug combinations in the treatment of TB is to:
Delay or prevent the emergence of resistance
Which statement about fluconazole is accurate?
•A. Does not penetrate the blood-brain barrier
•B. Is safe during pregnancy
•C. Primary route of elimination is renal
•D. Is only used topically
C. Primary route of elimination is renal
You have received the culture and sensitivity report from the lab. Your patient's urine is
growing E coli and the following is reported:
•Ampicillin Minimum Inhibitory Concentration (MIC) 38 mg/L
•Gentamicin MIC 20 mg/L
•Piperacillin MIC 4 mg/L
•Ciprofloxacin MIC 2.5 mg/L
Which of the following would you choose to treat the UTI?
Ciprofloxacin
A 55 year old man who has been on anticoagulant treatment for many years is diagnosed
with TB. Which of the following antimycobacterial agents would most likely induce
cytochrome P450 enzymes in the patient's liver thereby modify the effects of his
anticoagulant treatment?
Rifampin
Which drug is an antiviral that can be used to treat herpes simplex virus?
•A. Zanamivir
•B. Acyclovir
•C. Amphotericin B
•D. Ethambutol
, B. Acyclovir (others: valacyclovir, famciclovir)
Which of the following describes the mechanism of action of oseltamivir?
•A. selectively inhibits neuraminidase
•B. Therapeutic spectrum is limited to influenza A infections
•C. Inhibits protease
•D. It is not well understood
A. selectively inhibits neuraminidase
First generation Cephalosporins are best against which of the following organisms?
•A. Gram negative rods
•B. Gram positive cocci
•C. Fungi
•D. Anaerobes
B. Gram positive cocci
Isoniazid can cause serious adverse effects including:
neuropathy
Seizures Hepatitis
Peripheral
Cefepime is eliminated via
Tubular secretion and/or glomerular filtration
Which of the following is a common adverse effect of trimethoprim/ sulfamethoxazole
(TMP/SMZ)?
•A. Decreased prothrombin times in patients receiving warfarin
•B. Skin reactions
•C. Tendon rupture
•D. Constipation
