MCB 2050
Vesicle
Trafficking with
100% correct
answers 2025
ER Exit Site (ERES) - answer A distinct subdomain of the ER, located next
to the cis face of the Golgi.
Molecular machinery of ERES - answer Responsible for formation of
vesicles and proper packaging of vesicles with right cargo of proteins
Vesicle morphology - answer Small being about 20-50nm in diameter, a
fuzzy appearance on EM.
Coat proteins (COP) functions - answer 1. Mediate the curving of the
membrane on forming vesicle.
2. Recognize and package specific proteins in the forming vesicle.
COP categories - answer COPII -> assist in anterograde (forward)
transport from ERES to Golgi.
COPI -> assist in retrograde (backward) transport within Golgi and from
Golgi to ER.
Vesicle
Trafficking with
100% correct
answers 2025
ER Exit Site (ERES) - answer A distinct subdomain of the ER, located next
to the cis face of the Golgi.
Molecular machinery of ERES - answer Responsible for formation of
vesicles and proper packaging of vesicles with right cargo of proteins
Vesicle morphology - answer Small being about 20-50nm in diameter, a
fuzzy appearance on EM.
Coat proteins (COP) functions - answer 1. Mediate the curving of the
membrane on forming vesicle.
2. Recognize and package specific proteins in the forming vesicle.
COP categories - answer COPII -> assist in anterograde (forward)
transport from ERES to Golgi.
COPI -> assist in retrograde (backward) transport within Golgi and from
Golgi to ER.