Midterm myExam: myNR565/ myNR my565 myAdvanced
myPharmacology myCare myof mythe myFundamentals
myExam my|
Questions myand myVerified myAnswers my(2023/ my2024
Update)- Chamberlain
When myis myit myused my- myASCVD myRisk myScore my- myANSWER-In
mychildren mya myscreening myshould mybe mydone mybetween myages my9 myand
my11 myand mythen myagain myat myages my19 myand my21. myFor myadults myevery my5
myyears myafter mythe myage myof my20. mySome mypeople myare myat mygreater myrisk
mylike mythose mywith mydiabetes myand mya myrisk myscore mygreater mythan my7.5%
myand myshould mybe myscreened mymore myoften
ezetimibe- mywhen mycan myit mybe myused? my- myANSWER-
pregnancy/breastfeeding mycan mybe myuse myin mymonotherapy myor myas
adjunct mytherapy mywith mya mystatin myor mya myfibrate
my
What myis myezetimibe? my- myANSWER-Cholesterol myAbsorption
myInhibitor- mylowers mycholesterol mylevels myby mydecreasing mythe myamount
myof mycholesterol mythat myis myabsorbed myfrom mythe mysmall myintestine, myso
mythat mythere myis myless myintestinal mycholesterol mydelivered myto mythe myliver.
myDoes mynot myaffect mytriglycerides
lifestyle mychanges myfor myhigh mycholesterol my- myANSWER-Lifestyle
mychanges myare mynon mydrug mymeasures myused myto mylower myLDL. myFour
mymain myissues myare mydiet, myexercise, myweight mycontrol, myand mysmoking
mycessation
If mya mypatient mywanted myto myminimize myside myeffects, mywhich mydrug
myclassification myis mya mygood mychoice? my- myANSWER-Non-statins-
myfibrates, myEzetimibe, myBile myacid mysequestrants. myStatins myare
mygenerally mywell mytolerated myand myside myeffects myare myuncommon.
, Midterm myExam: myNR565/ myNR my565 myAdvanced
myPharmacology myCare myof mythe myFundamentals
myExam my|
Questions myand myVerified myAnswers my(2023/ my2024
mySome mypatients mydevelop myheadache, myflatulence, myconstipation, myor
Update)- Chamberlain
myGI mydisturbances, mybut mythese myeffects myare myusually mymild myand
mytransient
, Midterm myExam: myNR565/ myNR my565 myAdvanced
myPharmacology myCare myof mythe myFundamentals
myExam my|
Questions myand myVerified myAnswers my(2023/ my2024
Update)- Chamberlain
Therapeutic myaction myof myorganic mynitrates my(nitroglycerin) my-
myANSWER-direct myrelaxant myeffect myon myvascular mysmooth mymuscles,
myand mythe mydilation myof mycoronary myvessels myimproves myoxygen mysupply
myto mythe mymyocardium. myThe mydilation myof myperipheral myveins, myand myin
myhigher mydoses myperipheral myarteries, myreduces mypreload myand myafterload,
myand mythereby mylowers mymyocardial myoxygen myconsumption.
promote myvasodilation
Contraindications myfor myranolazine my- myANSWER-Agents mythat myinhibit
myCYP3A4 mycan myincrease mythe mylevels myof myranolazine myand mythereby
myincrease mythe myrisk myof mytorsades myde mypointes. myThese mythings
myinclude: mygrapefruit myjuice, myHIV myprotease myinhibitors, mymacrolide
myantibiotics, myazole myantifungal mydrugs, myand mysome myCCB. myMost
myCCB mybut mynot myamlodipine mycan myincrease mylevels myof myranolazine.
myDrugs mythat myprolong mythe myQT myinterval mycan myincrease mythe myrisk
myof mytorsades myde mypointes. my(quinidine, mysotalol).
At mywhat myage mycan mystatins mybe myprescribed? my- myANSWER-avoid
mystatin myuse myin mychildren myunder mythe myage myof my10
CCB myrole mywith myvariant myangina my- myANSWER-promote myrelaxation
myof mycoronary myartery myspasm, myincreasing mycardiac myoxygen mysupply
what mymedication mycan mybe myadded myfor mypatients mywith myworsening
mysymptoms myof myHF? my- myANSWER-aldosterone myantagonist-
mypromotes mymyocardial myremodeling myand myfibrosis, myhelp mywith
mysymptoms
, Midterm myExam: myNR565/ myNR my565 myAdvanced
myPharmacology myCare myof mythe myFundamentals
myExam my|
Questions myand myVerified myAnswers my(2023/ my2024
Update)- Chamberlain
CCB mystable myangina my- myANSWER-promote myrelaxation myof
myperipheral myarterioles, mydecreasing myafterload myand myreducing mycardiac
myoxygen mydemand
A my41 myyear myold mypatient mycomes myinto mythe myclinic mycomplaining myof
myincreased myheart myrate myafter mystarting mynitro mypatches myfor mystable
myangina. myWhat mywould myan myappropriate myresponse mybe?
1. lets mylower mythe mydose myand myfrequency myof myuse
2. I mywill myprescribe mya myBB myto myhelp mywith mythis
3. Next mytime mythis myhappens, mylie mydown myand mypractice mydeep
mybreathing, mythis mywill mybring myyour myheart myrate mydown my- myANSWER-
2- myI mywill myprescribe mya myBB myto myhelp mywith mythis
What mydo myCYP450 myinhibitors myand myreducers mydo mywhen mynot myused
mycorrectly/what mywould mypatient myexperience? my- myANSWER-increased
myside myeffects, myadverse myreactions myand mytoxicity
A my55 myyear myold mymale mycomes myinto mythe myclinic mywith mya mygouty
myarthritis. myHe mystates mythat myhe myhas myone myflareup mya myyear. myYour
myresponse myis:
1. I mywill myprescribe myyou myglucocorticoids myto myhelp mywith myinflammation
2. Lets mystart myyou myon myprophylactic mytherapy mycolchicine.
3. It mywill mybe myhelpful myto mytake myan myNSAID myto mystart mywith myto
myhelp myrelive mysome myinflammation. myI'll myprescribe mynaproxen. my-
myANSWER-3- myin mypatients mywith
myPharmacology myCare myof mythe myFundamentals
myExam my|
Questions myand myVerified myAnswers my(2023/ my2024
Update)- Chamberlain
When myis myit myused my- myASCVD myRisk myScore my- myANSWER-In
mychildren mya myscreening myshould mybe mydone mybetween myages my9 myand
my11 myand mythen myagain myat myages my19 myand my21. myFor myadults myevery my5
myyears myafter mythe myage myof my20. mySome mypeople myare myat mygreater myrisk
mylike mythose mywith mydiabetes myand mya myrisk myscore mygreater mythan my7.5%
myand myshould mybe myscreened mymore myoften
ezetimibe- mywhen mycan myit mybe myused? my- myANSWER-
pregnancy/breastfeeding mycan mybe myuse myin mymonotherapy myor myas
adjunct mytherapy mywith mya mystatin myor mya myfibrate
my
What myis myezetimibe? my- myANSWER-Cholesterol myAbsorption
myInhibitor- mylowers mycholesterol mylevels myby mydecreasing mythe myamount
myof mycholesterol mythat myis myabsorbed myfrom mythe mysmall myintestine, myso
mythat mythere myis myless myintestinal mycholesterol mydelivered myto mythe myliver.
myDoes mynot myaffect mytriglycerides
lifestyle mychanges myfor myhigh mycholesterol my- myANSWER-Lifestyle
mychanges myare mynon mydrug mymeasures myused myto mylower myLDL. myFour
mymain myissues myare mydiet, myexercise, myweight mycontrol, myand mysmoking
mycessation
If mya mypatient mywanted myto myminimize myside myeffects, mywhich mydrug
myclassification myis mya mygood mychoice? my- myANSWER-Non-statins-
myfibrates, myEzetimibe, myBile myacid mysequestrants. myStatins myare
mygenerally mywell mytolerated myand myside myeffects myare myuncommon.
, Midterm myExam: myNR565/ myNR my565 myAdvanced
myPharmacology myCare myof mythe myFundamentals
myExam my|
Questions myand myVerified myAnswers my(2023/ my2024
mySome mypatients mydevelop myheadache, myflatulence, myconstipation, myor
Update)- Chamberlain
myGI mydisturbances, mybut mythese myeffects myare myusually mymild myand
mytransient
, Midterm myExam: myNR565/ myNR my565 myAdvanced
myPharmacology myCare myof mythe myFundamentals
myExam my|
Questions myand myVerified myAnswers my(2023/ my2024
Update)- Chamberlain
Therapeutic myaction myof myorganic mynitrates my(nitroglycerin) my-
myANSWER-direct myrelaxant myeffect myon myvascular mysmooth mymuscles,
myand mythe mydilation myof mycoronary myvessels myimproves myoxygen mysupply
myto mythe mymyocardium. myThe mydilation myof myperipheral myveins, myand myin
myhigher mydoses myperipheral myarteries, myreduces mypreload myand myafterload,
myand mythereby mylowers mymyocardial myoxygen myconsumption.
promote myvasodilation
Contraindications myfor myranolazine my- myANSWER-Agents mythat myinhibit
myCYP3A4 mycan myincrease mythe mylevels myof myranolazine myand mythereby
myincrease mythe myrisk myof mytorsades myde mypointes. myThese mythings
myinclude: mygrapefruit myjuice, myHIV myprotease myinhibitors, mymacrolide
myantibiotics, myazole myantifungal mydrugs, myand mysome myCCB. myMost
myCCB mybut mynot myamlodipine mycan myincrease mylevels myof myranolazine.
myDrugs mythat myprolong mythe myQT myinterval mycan myincrease mythe myrisk
myof mytorsades myde mypointes. my(quinidine, mysotalol).
At mywhat myage mycan mystatins mybe myprescribed? my- myANSWER-avoid
mystatin myuse myin mychildren myunder mythe myage myof my10
CCB myrole mywith myvariant myangina my- myANSWER-promote myrelaxation
myof mycoronary myartery myspasm, myincreasing mycardiac myoxygen mysupply
what mymedication mycan mybe myadded myfor mypatients mywith myworsening
mysymptoms myof myHF? my- myANSWER-aldosterone myantagonist-
mypromotes mymyocardial myremodeling myand myfibrosis, myhelp mywith
mysymptoms
, Midterm myExam: myNR565/ myNR my565 myAdvanced
myPharmacology myCare myof mythe myFundamentals
myExam my|
Questions myand myVerified myAnswers my(2023/ my2024
Update)- Chamberlain
CCB mystable myangina my- myANSWER-promote myrelaxation myof
myperipheral myarterioles, mydecreasing myafterload myand myreducing mycardiac
myoxygen mydemand
A my41 myyear myold mypatient mycomes myinto mythe myclinic mycomplaining myof
myincreased myheart myrate myafter mystarting mynitro mypatches myfor mystable
myangina. myWhat mywould myan myappropriate myresponse mybe?
1. lets mylower mythe mydose myand myfrequency myof myuse
2. I mywill myprescribe mya myBB myto myhelp mywith mythis
3. Next mytime mythis myhappens, mylie mydown myand mypractice mydeep
mybreathing, mythis mywill mybring myyour myheart myrate mydown my- myANSWER-
2- myI mywill myprescribe mya myBB myto myhelp mywith mythis
What mydo myCYP450 myinhibitors myand myreducers mydo mywhen mynot myused
mycorrectly/what mywould mypatient myexperience? my- myANSWER-increased
myside myeffects, myadverse myreactions myand mytoxicity
A my55 myyear myold mymale mycomes myinto mythe myclinic mywith mya mygouty
myarthritis. myHe mystates mythat myhe myhas myone myflareup mya myyear. myYour
myresponse myis:
1. I mywill myprescribe myyou myglucocorticoids myto myhelp mywith myinflammation
2. Lets mystart myyou myon myprophylactic mytherapy mycolchicine.
3. It mywill mybe myhelpful myto mytake myan myNSAID myto mystart mywith myto
myhelp myrelive mysome myinflammation. myI'll myprescribe mynaproxen. my-
myANSWER-3- myin mypatients mywith
