PHC 7010 Exam 1 questions with
accurate answers
OLD EXAM QUESTION: The set of properties that characterize the fate of the drug administered to a
patient: - correct answer ✔✔pharmacokinetics
Pharmaco______________ is what the drug does to the body
Pharmaco______________ is what the body does to the drug - correct answer ✔✔pharmacodynamics
pharmacokinetics
OLD EXAM QUESTION: The set of properties that characterize the response of the target cells to the
drug: - correct answer ✔✔pharmacodynamics
OLD EXAM QUESTION: Nicotonic ACh receptors are associated with which of the following signaling
mechanism? - correct answer ✔✔Ligand-gated ion channels
OLD EXAM QUESTION: Which of the following signalling mechanisms involves phosphorylation of
substrate proteins and has receptors that are polypeptides with cytoplasmic enzyme domains? - correct
answer ✔✔transmembrane receptors
OLD EXAM QUESTION: Match the nicotinic ACh receptor with its timescale - correct answer
✔✔milliseconds
OLD EXAM QUESTION:Characteristics of intracellular receptor-mediated signalling may involve: - correct
answer ✔✔Interaction with highly lipophilic drugs
Heat shock protein 90
long response time (hours)
OLD EXAM QUESTION: Is this a pharmacodynamic or pharmacokinetic process? Alteration of the drug by
liver enzymes - correct answer ✔✔pharmacokinetic
, OLD EXAM QUESTION: Is this a pharmacodynamic or pharmacokinetic process? Drug metabolites are
excreted by urine - correct answer ✔✔pharmacokinetic
OLD EXAM QUESTION: Is this a pharmacodynamic or pharmacokinetic process? Movement of a drug
from the gut into general circulation - correct answer ✔✔pharmacokinetic
OLD EXAM QUESTION: Is this a pharmacodynamic or pharmacokinetic process? the drug causes dilation
of coronary vessels - correct answer ✔✔pharmacodynamic
OLD EXAM QUESTION: Is this a pharmacodynamic or pharmacokinetic process? the drug is readily
deposited into fat tissue - correct answer ✔✔pharmacokinetic
OLD EXAM QUESTION: A simple, reversible competitive antagonist is expected to acutely....... - correct
answer ✔✔reduce potency of an agonist
OLD EXAM QUESTION: Leukotrines cause bronchoconstriction (mediated at leukotrine receptors) in a
patient with asthma. When albuterol (acting at B receptors) is given to a patient during an asthma attack,
broncodilation usually results. Which of the following expressions best describes action of albuterol in
this situation? - correct answer ✔✔physiologic antagonist
OLD EXAM QUESTION: Histamine lowers blood pressure through vasodilation (acting on H1 receptors) If
epinephrine is taken at the same time arterial pressure can rise through vasoconstriction (acting on B
adrenergic receptors). Which of the following expressions best describes action of epinephrine in this
situation? - correct answer ✔✔physiologic antagonist
OLD EXAM QUESTION: What is the role of an inverse agonist? - correct answer ✔✔inactivate
consituitvely active receptors
OLD EXAM QUESTION: Which of the following terms best defines a drug that binds to a receptor, has no
intrinsic activity, and cannot be displaced by receptor agonist? - correct answer ✔✔Irreversible
antagonist
accurate answers
OLD EXAM QUESTION: The set of properties that characterize the fate of the drug administered to a
patient: - correct answer ✔✔pharmacokinetics
Pharmaco______________ is what the drug does to the body
Pharmaco______________ is what the body does to the drug - correct answer ✔✔pharmacodynamics
pharmacokinetics
OLD EXAM QUESTION: The set of properties that characterize the response of the target cells to the
drug: - correct answer ✔✔pharmacodynamics
OLD EXAM QUESTION: Nicotonic ACh receptors are associated with which of the following signaling
mechanism? - correct answer ✔✔Ligand-gated ion channels
OLD EXAM QUESTION: Which of the following signalling mechanisms involves phosphorylation of
substrate proteins and has receptors that are polypeptides with cytoplasmic enzyme domains? - correct
answer ✔✔transmembrane receptors
OLD EXAM QUESTION: Match the nicotinic ACh receptor with its timescale - correct answer
✔✔milliseconds
OLD EXAM QUESTION:Characteristics of intracellular receptor-mediated signalling may involve: - correct
answer ✔✔Interaction with highly lipophilic drugs
Heat shock protein 90
long response time (hours)
OLD EXAM QUESTION: Is this a pharmacodynamic or pharmacokinetic process? Alteration of the drug by
liver enzymes - correct answer ✔✔pharmacokinetic
, OLD EXAM QUESTION: Is this a pharmacodynamic or pharmacokinetic process? Drug metabolites are
excreted by urine - correct answer ✔✔pharmacokinetic
OLD EXAM QUESTION: Is this a pharmacodynamic or pharmacokinetic process? Movement of a drug
from the gut into general circulation - correct answer ✔✔pharmacokinetic
OLD EXAM QUESTION: Is this a pharmacodynamic or pharmacokinetic process? the drug causes dilation
of coronary vessels - correct answer ✔✔pharmacodynamic
OLD EXAM QUESTION: Is this a pharmacodynamic or pharmacokinetic process? the drug is readily
deposited into fat tissue - correct answer ✔✔pharmacokinetic
OLD EXAM QUESTION: A simple, reversible competitive antagonist is expected to acutely....... - correct
answer ✔✔reduce potency of an agonist
OLD EXAM QUESTION: Leukotrines cause bronchoconstriction (mediated at leukotrine receptors) in a
patient with asthma. When albuterol (acting at B receptors) is given to a patient during an asthma attack,
broncodilation usually results. Which of the following expressions best describes action of albuterol in
this situation? - correct answer ✔✔physiologic antagonist
OLD EXAM QUESTION: Histamine lowers blood pressure through vasodilation (acting on H1 receptors) If
epinephrine is taken at the same time arterial pressure can rise through vasoconstriction (acting on B
adrenergic receptors). Which of the following expressions best describes action of epinephrine in this
situation? - correct answer ✔✔physiologic antagonist
OLD EXAM QUESTION: What is the role of an inverse agonist? - correct answer ✔✔inactivate
consituitvely active receptors
OLD EXAM QUESTION: Which of the following terms best defines a drug that binds to a receptor, has no
intrinsic activity, and cannot be displaced by receptor agonist? - correct answer ✔✔Irreversible
antagonist
