Questions And Answers
The nurse is administering parenteral drugs. Which statement is true regarding parenteral drugs?
A. Parenteral drugs bypass the first-pass effect.
B. Absorption of parenteral drugs is affected by reduced blood flow to the stomach.
C. Absorption of parenteral drugs is faster when the stomach is empty.
D. Parenteral drugs exert their effects while circulating in the bloodstream. A. Parenteral
drugs bypass the first-pass effect.
Rationale: Drugs given by the parenteral route bypass the first-pass effect. Reduced blood flow
to the stomach and the presence of food in the stomach apply to enteral drugs (taken orally), not
to parenteral drugs. Parenteral drugs must be absorbed into cells and tissues from the circulation
before they can exert their effects: they do not exert their effects while circulating in the
bloodstream.
The nurse is administering medications to the patient who is in renal failure resulting from end-
stage renal disease. The nurse is aware that patients with kidney failure would most likely have
problems with which pharmacokinetic phase?
, ECPI NUR 138 Pharmacology Exam 1
Questions And Answers
A. Excretion
B. Absorption
C. Metabolism
D. Distribution A. Excretion
Rationale: The kidneys are the organs that are most responsible for drug excretion. Renal
function does not affect the absorption and distribution of a drug. Renal function may affect
metabolism of drugs to a small extent.
The patient is complaining of a headache and asks the nurse which over-the-counter medication
form would work the fastest to help reduce the pain. Which medication form will the nurse
suggest?
A. A tablet
B. A capsule
C. A powder
D. An enteric-coated tablet C. A powder
, ECPI NUR 138 Pharmacology Exam 1
Questions And Answers
Rationale: Of the types of oral medications listed, the powder form would be absorbed the
fastest, thus having a faster onset. The tablet, the capsule, and, finally, the enteric-coated tablet
would be absorbed next, in that order.
Which drugs would be affected by the first-pass effect? (Select all that apply.)
A. Sublingual nitroglycerin tablets
B. Levothyroxine (Synthroid) tablets
C. Diphenhydramine (Benadryl) elixir
D. Penicillin given by IV piggyback infusion
E. Morphine given by IV push injection
F. Esomeprazole (Nexium) capsules
G. Transdermal nicotine patches B. Levothyroxine (Synthroid) tablets
C. Diphenhydramine (Benadryl) elixir
F. Esomeprazole (Nexium) capsules
For accurate medication administration to pediatric patients, the nurse must take into account
which criteria?
, ECPI NUR 138 Pharmacology Exam 1
Questions And Answers
A. Renal output
B. Height
C. Body temperature
D. Organ maturity D. Organ maturity
Rationale: To administer medications to pediatric patients accurately, one must take into account
organ maturity, body surface area, age, and weight. The other options are incorrect: renal output
and body temperature are not considerations, and height alone is not sufficient.
During discharge patient teaching, the nurse reviews prescriptions with a patient. Which
statement is correct about refills for an analgesic that is classified as Schedule C-III?
A. The patient may have no more than five refills in a 6-month period.
B. Refills are allowed only by written prescription.
C. Written prescriptions expire in 12 months.
D. No prescription refills are permitted. A. The patient may have no more than five refills
in a 6-month period.