10/22/24, 12:07 PM Advanced Physiology & Pathophysiology |2024-2025 update |Advanced Physiology and Pathophysiology Essentials for Clini…
Advanced Physiology & Pathophysiology
|2024-2025 update |Advanced Physiology and
Pathophysiology Essentials for Clinical Practice|
get it A+
Terms in this set (250)
not only cellular and organ changes that occur
What is
with disease, but with the effects that these
pathophysiology?
changes have on total body function
decrease in size of tissue
organs resulting from a
decrease in cell size or in
number of cells
causes include disuse, loss
of trophic stimuli (i.e. loss of
innervation), insufficient
Atrophy nutrients, decreased blood
flow, persistent cell injury,
and aging
cells decrease cellular
machinery, decrease
oxygen/glucose needs,
decrease number of
organelles
https://quizlet.com/960758171/advanced-physiology-pathophysiology-2024-2025-update-advanced-physiology-and-pathophysiology-essentials-f… 1/60
,10/22/24, 12:07 PM Advanced Physiology & Pathophysiology |2024-2025 update |Advanced Physiology and Pathophysiology Essentials for Clini…
increase in cell size, and
thus an increase in amount
of functioning tissue mass
results from an increased
workload imposed on an
organ or body part
Hypertrophy
involves an increase in the
functional components of
the cell that allows it to
achieve equilibrium b/w
demand and functional
capacity
increase in number of cells
in an organ or tissue
∙can only occur in tissues
that are capable of mitotic
division
controlled process that
occurs in response to an
appropriate stimulus and
ceases after stimulus has
Hyperplasia
been removed
more dangerous than
hypertrophy → b/c of
increased division, increased
risk of cancer
example: prostate,
uterus/breast tissue in
pregnancy/puberty
https://quizlet.com/960758171/advanced-physiology-pathophysiology-2024-2025-update-advanced-physiology-and-pathophysiology-essentials-f… 2/60
,10/22/24, 12:07 PM Advanced Physiology & Pathophysiology |2024-2025 update |Advanced Physiology and Pathophysiology Essentials for Clini…
reversible change in which
one adult cell type is
replaced by another adult
cell type
∙only kind of cell of that is
replaced is present, i.e.
epithelial cells are replaced
by a different type of
epithelial cell
thought to involve the
Metaplasia
reprogramming of
undifferentiated stem cells
that are present in tissue
usually occurs in response to
chronic irritation and
inflammation which allows
for substitution of cells that
are better able to survive
seen in Barrett's esophagus
https://quizlet.com/960758171/advanced-physiology-pathophysiology-2024-2025-update-advanced-physiology-and-pathophysiology-essentials-f… 3/60
, 10/22/24, 12:07 PM Advanced Physiology & Pathophysiology |2024-2025 update |Advanced Physiology and Pathophysiology Essentials for Clini…
characterized by deranged
cell growth of a specific
tissue that results in cells
that vary in size, shape and
appearance
∙thought of as replacement
of mature cell by immature
cells, that can differentiate
into different cell types
involves sequential
Dysplasia
mutations in proliferating
cell populations
pattern is most frequently
encountered in metaplastic
squamous epithelium of
respiratory tract and uterine
cervix
strongly implicated as a
precursor to cancer
https://quizlet.com/960758171/advanced-physiology-pathophysiology-2024-2025-update-advanced-physiology-and-pathophysiology-essentials-f… 4/60
Advanced Physiology & Pathophysiology
|2024-2025 update |Advanced Physiology and
Pathophysiology Essentials for Clinical Practice|
get it A+
Terms in this set (250)
not only cellular and organ changes that occur
What is
with disease, but with the effects that these
pathophysiology?
changes have on total body function
decrease in size of tissue
organs resulting from a
decrease in cell size or in
number of cells
causes include disuse, loss
of trophic stimuli (i.e. loss of
innervation), insufficient
Atrophy nutrients, decreased blood
flow, persistent cell injury,
and aging
cells decrease cellular
machinery, decrease
oxygen/glucose needs,
decrease number of
organelles
https://quizlet.com/960758171/advanced-physiology-pathophysiology-2024-2025-update-advanced-physiology-and-pathophysiology-essentials-f… 1/60
,10/22/24, 12:07 PM Advanced Physiology & Pathophysiology |2024-2025 update |Advanced Physiology and Pathophysiology Essentials for Clini…
increase in cell size, and
thus an increase in amount
of functioning tissue mass
results from an increased
workload imposed on an
organ or body part
Hypertrophy
involves an increase in the
functional components of
the cell that allows it to
achieve equilibrium b/w
demand and functional
capacity
increase in number of cells
in an organ or tissue
∙can only occur in tissues
that are capable of mitotic
division
controlled process that
occurs in response to an
appropriate stimulus and
ceases after stimulus has
Hyperplasia
been removed
more dangerous than
hypertrophy → b/c of
increased division, increased
risk of cancer
example: prostate,
uterus/breast tissue in
pregnancy/puberty
https://quizlet.com/960758171/advanced-physiology-pathophysiology-2024-2025-update-advanced-physiology-and-pathophysiology-essentials-f… 2/60
,10/22/24, 12:07 PM Advanced Physiology & Pathophysiology |2024-2025 update |Advanced Physiology and Pathophysiology Essentials for Clini…
reversible change in which
one adult cell type is
replaced by another adult
cell type
∙only kind of cell of that is
replaced is present, i.e.
epithelial cells are replaced
by a different type of
epithelial cell
thought to involve the
Metaplasia
reprogramming of
undifferentiated stem cells
that are present in tissue
usually occurs in response to
chronic irritation and
inflammation which allows
for substitution of cells that
are better able to survive
seen in Barrett's esophagus
https://quizlet.com/960758171/advanced-physiology-pathophysiology-2024-2025-update-advanced-physiology-and-pathophysiology-essentials-f… 3/60
, 10/22/24, 12:07 PM Advanced Physiology & Pathophysiology |2024-2025 update |Advanced Physiology and Pathophysiology Essentials for Clini…
characterized by deranged
cell growth of a specific
tissue that results in cells
that vary in size, shape and
appearance
∙thought of as replacement
of mature cell by immature
cells, that can differentiate
into different cell types
involves sequential
Dysplasia
mutations in proliferating
cell populations
pattern is most frequently
encountered in metaplastic
squamous epithelium of
respiratory tract and uterine
cervix
strongly implicated as a
precursor to cancer
https://quizlet.com/960758171/advanced-physiology-pathophysiology-2024-2025-update-advanced-physiology-and-pathophysiology-essentials-f… 4/60
