Advanced Pharmacology Test 2 Module
4 Cardiovascular and Dyslipidemia quiz
test with correct answers
ACE-Inhibitors end in: - CORRECT ANSWERS-"-pril"
lisinoprin
enalapril
captopril
ADE of ACE-I - CORRECT ANSWERS-Cough (20%)
hyperkalemia (caution in K+ sparing diuretics)
AKI
Angioedema
ADE of Minoxidil - CORRECT ANSWERS-hypertrichosis (Rogaine!)
significant Na+ and H2O reabsorption, worsening CHF
ADE of thiazide diuretics - CORRECT ANSWERS-low K+, Mg+, Na+
high Ca+, uric acid (gout!), cholesterol
photosensitivity, rash
ADE/Patient teaching needed for Alpha-1 blockers - CORRECT ANSWERS-first dose
effect- severe orthostatic hypotension or syncope within several hours of first dose
Alpha receptors are located where? - CORRECT ANSWERS-arteries and veins
Amiodarone ADE - CORRECT ANSWERS-MANY drug interactions (statins, digoxin,
warfarin)
Bradycardia or heart block
Blocks conversion of T4 to T3- hyper or hypothyroidism
Accumulates in many tissues:
- pulmonary toxicity
- photodermatitis, blue-grey skin color
- corneal microdeposits
- halos in peripheral vision
, - abnormal liver function
Amiodarone is a ___________ channel blocker - CORRECT ANSWERS-Potassium
Amiodarone MOA - CORRECT ANSWERS-prolongs the refractory period via blockade
of K+ channels required for repolarization of cardiac AP
prolongs QT interval
slows HR and AV node conduction
Angiotensin Receptor Blockers (ARBs) end in ____________ - CORRECT ANSWERS-
"sartan"
losartan
valsartan
candesartan
Angiotensin Receptor Blockers ADE - CORRECT ANSWERS-Renal insufficiency/acute
injury
hyperkalemia (caution in K+ sparing diuretics)
Angioedema (less than ACE-I)
Cough (much less than ACE-I)
Angiotensin Receptor Blockers Contraindications - CORRECT ANSWERS-Pregnancy
Renal artery stenosis
caution in renal dysfunction
Antiarrhythmic: DIGOXIN MOA - CORRECT ANSWERS-shortens atrial action potential
and increases AV node refractory period
used to terminate AV node dysrhythmias and to control ventricular response to a-fib
Antiarrhythmics: Calcium Channel Blockers are used for treatment of: - CORRECT
ANSWERS-ventricular arrhythmias and a-fib
Antiarrhythmics: Sodium Channel Blockers and Beta Blockers are mainly used for: -
CORRECT ANSWERS-ventricular dysrhythmias
ARBs do not block ______________, resulting in less ADE of ____________ -
CORRECT ANSWERS-don't block bradykinin (so doesn't build up in lungs)
less cough ADE
Benefit of long-term thiazide use - CORRECT ANSWERS-decreased peripheral
vascular resistance
Beta 2 affects peripheral blood flow and may cause: - CORRECT ANSWERS-
worsening intermittent claudication
Raynaud's
4 Cardiovascular and Dyslipidemia quiz
test with correct answers
ACE-Inhibitors end in: - CORRECT ANSWERS-"-pril"
lisinoprin
enalapril
captopril
ADE of ACE-I - CORRECT ANSWERS-Cough (20%)
hyperkalemia (caution in K+ sparing diuretics)
AKI
Angioedema
ADE of Minoxidil - CORRECT ANSWERS-hypertrichosis (Rogaine!)
significant Na+ and H2O reabsorption, worsening CHF
ADE of thiazide diuretics - CORRECT ANSWERS-low K+, Mg+, Na+
high Ca+, uric acid (gout!), cholesterol
photosensitivity, rash
ADE/Patient teaching needed for Alpha-1 blockers - CORRECT ANSWERS-first dose
effect- severe orthostatic hypotension or syncope within several hours of first dose
Alpha receptors are located where? - CORRECT ANSWERS-arteries and veins
Amiodarone ADE - CORRECT ANSWERS-MANY drug interactions (statins, digoxin,
warfarin)
Bradycardia or heart block
Blocks conversion of T4 to T3- hyper or hypothyroidism
Accumulates in many tissues:
- pulmonary toxicity
- photodermatitis, blue-grey skin color
- corneal microdeposits
- halos in peripheral vision
, - abnormal liver function
Amiodarone is a ___________ channel blocker - CORRECT ANSWERS-Potassium
Amiodarone MOA - CORRECT ANSWERS-prolongs the refractory period via blockade
of K+ channels required for repolarization of cardiac AP
prolongs QT interval
slows HR and AV node conduction
Angiotensin Receptor Blockers (ARBs) end in ____________ - CORRECT ANSWERS-
"sartan"
losartan
valsartan
candesartan
Angiotensin Receptor Blockers ADE - CORRECT ANSWERS-Renal insufficiency/acute
injury
hyperkalemia (caution in K+ sparing diuretics)
Angioedema (less than ACE-I)
Cough (much less than ACE-I)
Angiotensin Receptor Blockers Contraindications - CORRECT ANSWERS-Pregnancy
Renal artery stenosis
caution in renal dysfunction
Antiarrhythmic: DIGOXIN MOA - CORRECT ANSWERS-shortens atrial action potential
and increases AV node refractory period
used to terminate AV node dysrhythmias and to control ventricular response to a-fib
Antiarrhythmics: Calcium Channel Blockers are used for treatment of: - CORRECT
ANSWERS-ventricular arrhythmias and a-fib
Antiarrhythmics: Sodium Channel Blockers and Beta Blockers are mainly used for: -
CORRECT ANSWERS-ventricular dysrhythmias
ARBs do not block ______________, resulting in less ADE of ____________ -
CORRECT ANSWERS-don't block bradykinin (so doesn't build up in lungs)
less cough ADE
Benefit of long-term thiazide use - CORRECT ANSWERS-decreased peripheral
vascular resistance
Beta 2 affects peripheral blood flow and may cause: - CORRECT ANSWERS-
worsening intermittent claudication
Raynaud's
