Psychopharm Chapter 2 Exam Questions and Answers Latest Update Graded A+

Psychopharm Chapter 2 Exam Questions and Answers Latest Update Graded A+ The study of how a drug interacts with a receptor is termed - Answers Pharmacodynamics The naturally occurring compounds that bind to receptors are termed - Answers Transmitters A ? Can usually bind to many ? - Answers Neurotransmitter Receptors A ? Usually binds to only one ? - Answers Receptor Neurotransmitter New advances in pharmacology enable for the first time the development of drugs that bind to - Answers One receptor only Remarkably molecular biological techniques such as receptor cloning have allowed for the development of drugs that are more selective than endogenous - Answers Ligands and neurotransmitters A drug that exerts an effect similar to and occupies the same receptor site as the naturally occurring compound is termed - Answers An agonist A drug that blocks the effect of and occupies the same receptor site as the naturally occurring compound is termed - Answers Antagonist An ion channel within a postsynaptic receptor responds to binding of a neurotransmitter by altering: - Answers b. its permeability to, but not selectivity for, ions. The anxiolytic anxiety reducing effect of benzos such as diazepam occurs through - Answers Agonist action st the gaba receptor The benzo such as diazepam bind at - Answers A different site on the receptor as the endogenous neurotransmitter to facilitate the action of the neurotransmitter The benzo antagonist flumazenil binds at the same receptor as the - Answers Benzo to block the action of the benzo G protein coupled receptors respond to binding of a neurotransmitter by altering - Answers Ion channel fx Energy metabolism of the neural cell Cell division (All) G proteins can control the following cellular fxs - Answers Opening and closing of Ion channels Energy metabolism of neural cell Neural cell division (All) In metabotropic receptors - Answers The activated extracellular receptor in turn activates the G protein Membrane spanning receptor proteins include - Answers Both G protein coupled receptors and carrier transport proteins Drugs that block the action of carrier proteins would be expected to ? ; drugs that facilitate the action of carrier proteins would be expected to ? - Answers Increase the level of neurot in the synapse; decrease the level of neuro t in synapse Based on the concept of homeostatic control you might expect drugs that block the action of carrier proteins to ? The number of post synaptic receptors for the endogenous neurotransmitter further you might expect drugs that facilitate the action of carrier proteins to blank the number of post synaptic receptors for the endogenous neurotransmitter - Answers Decrease; increase Exposure to a drug that inhibits the breakdown of a neurotransmitter (NT): - Answers increases the level of NT by inhibiting breakdown in the synapse; an example of such a drug is an acetylcholine esterase inhibitor