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MCPHS Psychopharmacology Quiz 3

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MCPHS Psychopharmacology Quiz 3 Lecturez1:zCancerz-zCORRECTzANSWER- Cisplatinz-zCORRECTzANSWER-chemozdrug Methotrexatez-zCORRECTzANSWER-chemozdrug Tamoxifenz-zCORRECTzANSWER-chemozdrug Vincristinez-zCORRECTzANSWER-chemozdrug Cyclosporinez-zCORRECTzANSWER-chemozdrug Epoetinzalfaz(Epogen,zProcrit)z-zCORRECTzANSWER-treatszanemiaz usedzforzcancerzpatients Neulastaz-zCORRECTzANSWER-colonyzstimulatingzfactors decreaseszthezriskzofzincidencezofzinfectionzinzcancerzpatients Neupogenz-zCORRECTzANSWER-colonyzstimulatingzfactors decreaseszthezriskzofzincidencezofzinfectionzinzcancerzpatients Dronabinolz(Marinol)z-zCORRECTzANSWER-Cannabinoidzgivenz*afterzchemo*zforzCINVzandzaszanzappetitezstimulant Canzcausezdissociation/dysphoria,zhypotension,ztachycardia Megestrolzacetatez*(Megace)*z-zCORRECTzANSWER-N&Vzmedication;zazprogestinzthatzactszaszanzappetitezstimulant,z*not*zappropriatezforzptszwithzprostatezcancerzorzptszwithzhyperglycemia Ondansetronz(Zofran)z-zCORRECTzANSWER-antiemeticzgivenz*before*zadministrationzofzchemotherapyztozpreventzCINV Dexamethasonez-zCORRECTzANSWER-steroidzcanzgivenz*beforezorzafter*zadministrationzofzchemotherapy Cisplatinzleadsztoz______ztoxicitiyz-zCORRECTzANSWER-renal Bleomycinzleadsztoz_______ztoxicityz-zCORRECTzANSWER-lung Doxorubicin/daunorubicinzleadsztoz______ztoxicityz-zCORRECTzANSWER-cardio Vincristinezleadsztoz_______ztoxicityz-zCORRECTzANSWER-neuro Methotrexatezleadsztoz_______ztoxicityz-zCORRECTzANSWER-hepato Activityzrestrictionszforzneuropathyzinzcancerzptsz-zCORRECTzANSWER-avoidztreadmill Activityzrestrictionszforzosteoporosiszorzbonezmetastaseszinzcancerzptsz-zCORRECTzANSWER-avoidzhighzimpactzexercise Activityzrestrictionszforzneutropeniazinzcancerzptsz-zCORRECTzANSWER-avoidzswimming Activityzrestrictionszforzmusclezwastingzinzcancerzptsz-zCORRECTzANSWER-limitzresistiveztrainingztozveryzlightzweight Activityzrestrictionszforzcardiotoxiczchemozinzcancerzptsz-zCORRECTzANSWER-mayzrequirezcardiaczmonitoring Activityzrestrictionszforzanemiazinzcancerzptsz-zCORRECTzANSWER-fatigue Activityzrestrictionszforzthrombocytopeniazinzcancerzptsz-zCORRECTzANSWER-avoidzimpactztraining Whatziszthezmostzcommonzdosezlimitingztoxicityzinzchemotherapy?z-zCORRECTzANSWER-bonezmarrowzsuppression Thrombocytopeniaz-zCORRECTzANSWER-lowzplateletzcount Thezlowerzthezplateletzcountzthezhigherzthezbleedingzrisk Extremelyzlowzplateletzcountszlimitzpatients' physicalzactivityzespzifz50,000/mm3 Neutropeniaz-zCORRECTzANSWER-azdecreasedznumberzofzneutrophilsz(1500/mm3) Absolutezneutrophilzcountz(ANC)zmeasureszinfectionzsusceptibility ↓neutrophilzcountz↑riskzofzinfection Colonyzstimulatingzfactorsz-zCORRECTzANSWER-•zTypicallyzusedztozspeedzrecoveryzfrom myelosuppressivezchemotherapy •zStimulatezgrowthzofznewzwhitezbloodzcells Lecturez2:zAnesthesiaz-zCORRECTzANSWER- Whatziszspasticity?z-zCORRECTzANSWER-Increasedzmuscleztonezdueztozresistancezofzpassivezmovementzofzlimb Followedzbyzsuddenzrelaxationz

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MCPHS Psychopharmacology Quiz 3


Lecturez1:zCancerz-zCORRECTzANSWER-



Cisplatinz-zCORRECTzANSWER-chemozdrug



Methotrexatez-zCORRECTzANSWER-chemozdrug



Tamoxifenz-zCORRECTzANSWER-chemozdrug



Vincristinez-zCORRECTzANSWER-chemozdrug



Cyclosporinez-zCORRECTzANSWER-chemozdrug



Epoetinzalfaz(Epogen,zProcrit)z-zCORRECTzANSWER-treatszanemiaz



usedzforzcancerzpatients



Neulastaz-zCORRECTzANSWER-colonyzstimulatingzfactors

decreaseszthezriskzofzincidencezofzinfectionzinzcancerzpatients



Neupogenz-zCORRECTzANSWER-colonyzstimulatingzfactors

decreaseszthezriskzofzincidencezofzinfectionzinzcancerzpatients



Dronabinolz(Marinol)z-zCORRECTzANSWER-
Cannabinoidzgivenz*afterzchemo*zforzCINVzandzaszanzappetitezstimulant

Canzcausezdissociation/dysphoria,zhypotension,ztachycardia

,Megestrolzacetatez*(Megace)*z-zCORRECTzANSWER-
N&Vzmedication;zazprogestinzthatzactszaszanzappetitezstimulant,z*not*zappropriatezforzptszwithzprostatezc
ancerzorzptszwithzhyperglycemia



Ondansetronz(Zofran)z-zCORRECTzANSWER-
antiemeticzgivenz*before*zadministrationzofzchemotherapyztozpreventzCINV



Dexamethasonez-zCORRECTzANSWER-steroidzcanzgivenz*beforezorzafter*zadministrationzofzchemotherapy



Cisplatinzleadsztoz______ztoxicitiyz-zCORRECTzANSWER-renal



Bleomycinzleadsztoz_______ztoxicityz-zCORRECTzANSWER-lung



Doxorubicin/daunorubicinzleadsztoz______ztoxicityz-zCORRECTzANSWER-cardio



Vincristinezleadsztoz_______ztoxicityz-zCORRECTzANSWER-neuro



Methotrexatezleadsztoz_______ztoxicityz-zCORRECTzANSWER-hepato



Activityzrestrictionszforzneuropathyzinzcancerzptsz-zCORRECTzANSWER-avoidztreadmill



Activityzrestrictionszforzosteoporosiszorzbonezmetastaseszinzcancerzptsz-zCORRECTzANSWER-
avoidzhighzimpactzexercise



Activityzrestrictionszforzneutropeniazinzcancerzptsz-zCORRECTzANSWER-avoidzswimming



Activityzrestrictionszforzmusclezwastingzinzcancerzptsz-zCORRECTzANSWER-
limitzresistiveztrainingztozveryzlightzweight



Activityzrestrictionszforzcardiotoxiczchemozinzcancerzptsz-zCORRECTzANSWER-
mayzrequirezcardiaczmonitoring

, Activityzrestrictionszforzanemiazinzcancerzptsz-zCORRECTzANSWER-fatigue



Activityzrestrictionszforzthrombocytopeniazinzcancerzptsz-zCORRECTzANSWER-avoidzimpactztraining



Whatziszthezmostzcommonzdosezlimitingztoxicityzinzchemotherapy?z-zCORRECTzANSWER-
bonezmarrowzsuppression



Thrombocytopeniaz-zCORRECTzANSWER-lowzplateletzcount



Thezlowerzthezplateletzcountzthezhigherzthezbleedingzrisk



Extremelyzlowzplateletzcountszlimitzpatients'

physicalzactivityzespzifz<50,000/mm3



Neutropeniaz-zCORRECTzANSWER-azdecreasedznumberzofzneutrophilsz(<1500/mm3)



Absolutezneutrophilzcountz(ANC)zmeasureszinfectionzsusceptibility

↓neutrophilzcountz↑riskzofzinfection



Colonyzstimulatingzfactorsz-zCORRECTzANSWER-•zTypicallyzusedztozspeedzrecoveryzfrom

myelosuppressivezchemotherapy

•zStimulatezgrowthzofznewzwhitezbloodzcells



Lecturez2:zAnesthesiaz-zCORRECTzANSWER-



Whatziszspasticity?z-zCORRECTzANSWER-
Increasedzmuscleztonezdueztozresistancezofzpassivezmovementzofzlimb

Followedzbyzsuddenzrelaxationz

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