NR 507 midterm { 507 Questions And Answers] GRADED A
2024
Hives (urticaria) are an example of a: - CORRECT ANSWER Type 1 hypersensitivity
reaction.
Anaphylaxis is what type of reaction? - CORRECT ANSWER type 1 hypersensitivity
Which of the following are considered the "first responders" of the innate immune
system? - CORRECT ANSWER neutrophils
Allergic contact dermatitis is an example of what type of
hypersensitivity reaction. - CORRECT ANSWER type 4 hypersensitivity reaction
Type 2 (Cytotoxic) hypersensitivity reactions are mediated by: - CORRECT
ANSWER IgG or IgM
Type 1 hypersensitivity reaction is mediated by - CORRECT ANSWER IgE
Allergic asthma is an example of - CORRECT ANSWER type 1 hypersensitivity
reaction
type 2 hypersensitivity - CORRECT ANSWER tissue specific
Primary effector cells of type 2 - CORRECT ANSWER macrophages
Examples of type 2 reactions - CORRECT ANSWER drug allergies, hemolytic
anemia, blood transfusion mismatch, allergies against infectious agents
Type 2 causes - CORRECT ANSWER The cell to be destroyed by the antibody
Cell destruction through phagocytosis by macrophages
Damage to the cell by neutrophils triggering phagocytosis
Natural killer cells to release toxic substances that destroy the target cell
Malfunction of the cell without destruction
Type 3 hypersensitivity reaction - CORRECT ANSWER antigen-antibody response
,Where does the antibody bind to the antigen in type 3 response? - CORRECT
ANSWER in blood or body fluids and then circulates to tissue
Where does the antibody bind to the antigen in type 1, 2, and 4? - CORRECT
ANSWER on cell surface
Primary effector cell in type 3 - CORRECT ANSWER neutrophils
example of type 3 reaction - CORRECT ANSWER serum sickness
type 4 hypersensitivity reaction - CORRECT ANSWER cell-mediated response
primary mediators of type 4 - CORRECT ANSWER lymphocytes and macrophages
type 4 mediated by - CORRECT ANSWER T lymphocytes and do not use antibodies
example of type 4 - CORRECT ANSWER localized contact dermatitis (poison ivy)
Damage occurs with ABO incompatibility because: - CORRECT ANSWER
Complement damages RBC membrane causing cell lysis.
Which of the following is the underlying pathology for hay fever? - CORRECT
ANSWER mast cell degranulation
The diagnosis for an individual who presents to the office with sudden swollen
lips and eyes, shortness of breath and throat tightness after a bee sting is: -
CORRECT ANSWER anaphylaxis
Which of the following assessment findings would be expected in a patient who
presents with urticaria? - CORRECT ANSWER Eosinophilia.
An example of a primary immunodeficiency is: - CORRECT ANSWER Chronic
Granulomatous Disease.
what is a predominant cause of secondary immune deficiencies worldwide. -
CORRECT ANSWER Malnutrition
Which of the following is an autoimmune disease? - CORRECT ANSWER Systemic
Lupus Erythematosus (SLE).
Which is true about a primary immunodeficiency? - CORRECT ANSWER It is the
result of a single gene defect. (genetics)
,Examples of secondary immunodeficiency - CORRECT ANSWER HIV, cancer
Secondary immunodeficiency caused by - CORRECT ANSWER external to immune
system
examples of primary immunodeficiency - CORRECT ANSWER Chronic
granulomatous Disease of Childhood
DiGeorge Syndrome
Familial Mediterranean fever
Job Syndrome
Common Variable Immunodeficiency
examples of secondary immunodeficiency - CORRECT ANSWER Human
Immunodeficiency Virus
Pneumocystis Carinii
Pneumonia
Sinus infection
Lung cancer
Select the best statement below that describes a primary immunodeficiency: -
CORRECT ANSWER Are less common and occur due to a defect on the
development of the immune system.
Cancer is a secondary immunodeficiency. - CORRECT ANSWER true
Sinusitis is considered a primary immunodeficiency. - CORRECT ANSWER false
A patient with human immunodeficiency virus (HIV) was admitted to the acute
care facility with difficulty breathing. He is diagnosed with Pneumocytis carinii.
Pneumocystis carinii an example of: - CORRECT ANSWER secondary immune
disease
Which of the following findings can be used to diagnose Systemic Lupus
Erythematosus (SLE)? - CORRECT ANSWER Facial rash confined to the cheeks.
A renal disease most often associated with autoimmunity is - CORRECT ANSWER
Glomerulonephritis.
The major immune system change associated with Sjogren's Syndrome is: -
CORRECT ANSWER Autoantibodies and auto-reactive T-cells against apoptotic
cells.
, Which of the following can depress a person's normal immune function? -
CORRECT ANSWER Psychological Stress
Which of the following assessment findings would support a diagnosis of
Rheumatoid Arthritis (RA)? - CORRECT ANSWER Swollen metacarpophalangeal
joints.
Which of the following statements best describes the symptoms of Systemic
Lupus Erythematosus (SLE). - CORRECT ANSWER Tissue inflammation, vasculitis,
rash, tissue inflammation.
The presence of a low number of autoantibodies is an indicator that the individual
will develop an autoimmune disease. - CORRECT ANSWER false *does not
indicate
The following immune components can be involved in autoimmune diseases: T-
Cells, B-cells and autoantibodies. - CORRECT ANSWER true
Which of the following microcytic anemias is characterized by hyperchromic
RBCs? - CORRECT ANSWER Hereditary spherocytosis.
Which of the following is NOT a clinical characteristic of anemia? - CORRECT
ANSWER bradycardia
Which of the following is considered a microcytic anemia? - CORRECT ANSWER
Iron deficiency.
Which of the following indices measures the average size of red blood cells? -
CORRECT ANSWER Mean Corpuscular Volume (MCV).
What is anemia? - CORRECT ANSWER reduction in the total number of circulating
red blood cells (RBCs) and/or a decrease in hemoglobin (Hb) amount or function
Anemia can be caused by - CORRECT ANSWER 1) impaired RBC production, 2)
excessive blood loss, 3) increased RBC destruction OR any combination of the
three.
Microcytic anemia - CORRECT ANSWER (MCV<80 fL) describes RBCs that are
small.
Examples of microcytic anemia - CORRECT ANSWER Iron deficiency
2024
Hives (urticaria) are an example of a: - CORRECT ANSWER Type 1 hypersensitivity
reaction.
Anaphylaxis is what type of reaction? - CORRECT ANSWER type 1 hypersensitivity
Which of the following are considered the "first responders" of the innate immune
system? - CORRECT ANSWER neutrophils
Allergic contact dermatitis is an example of what type of
hypersensitivity reaction. - CORRECT ANSWER type 4 hypersensitivity reaction
Type 2 (Cytotoxic) hypersensitivity reactions are mediated by: - CORRECT
ANSWER IgG or IgM
Type 1 hypersensitivity reaction is mediated by - CORRECT ANSWER IgE
Allergic asthma is an example of - CORRECT ANSWER type 1 hypersensitivity
reaction
type 2 hypersensitivity - CORRECT ANSWER tissue specific
Primary effector cells of type 2 - CORRECT ANSWER macrophages
Examples of type 2 reactions - CORRECT ANSWER drug allergies, hemolytic
anemia, blood transfusion mismatch, allergies against infectious agents
Type 2 causes - CORRECT ANSWER The cell to be destroyed by the antibody
Cell destruction through phagocytosis by macrophages
Damage to the cell by neutrophils triggering phagocytosis
Natural killer cells to release toxic substances that destroy the target cell
Malfunction of the cell without destruction
Type 3 hypersensitivity reaction - CORRECT ANSWER antigen-antibody response
,Where does the antibody bind to the antigen in type 3 response? - CORRECT
ANSWER in blood or body fluids and then circulates to tissue
Where does the antibody bind to the antigen in type 1, 2, and 4? - CORRECT
ANSWER on cell surface
Primary effector cell in type 3 - CORRECT ANSWER neutrophils
example of type 3 reaction - CORRECT ANSWER serum sickness
type 4 hypersensitivity reaction - CORRECT ANSWER cell-mediated response
primary mediators of type 4 - CORRECT ANSWER lymphocytes and macrophages
type 4 mediated by - CORRECT ANSWER T lymphocytes and do not use antibodies
example of type 4 - CORRECT ANSWER localized contact dermatitis (poison ivy)
Damage occurs with ABO incompatibility because: - CORRECT ANSWER
Complement damages RBC membrane causing cell lysis.
Which of the following is the underlying pathology for hay fever? - CORRECT
ANSWER mast cell degranulation
The diagnosis for an individual who presents to the office with sudden swollen
lips and eyes, shortness of breath and throat tightness after a bee sting is: -
CORRECT ANSWER anaphylaxis
Which of the following assessment findings would be expected in a patient who
presents with urticaria? - CORRECT ANSWER Eosinophilia.
An example of a primary immunodeficiency is: - CORRECT ANSWER Chronic
Granulomatous Disease.
what is a predominant cause of secondary immune deficiencies worldwide. -
CORRECT ANSWER Malnutrition
Which of the following is an autoimmune disease? - CORRECT ANSWER Systemic
Lupus Erythematosus (SLE).
Which is true about a primary immunodeficiency? - CORRECT ANSWER It is the
result of a single gene defect. (genetics)
,Examples of secondary immunodeficiency - CORRECT ANSWER HIV, cancer
Secondary immunodeficiency caused by - CORRECT ANSWER external to immune
system
examples of primary immunodeficiency - CORRECT ANSWER Chronic
granulomatous Disease of Childhood
DiGeorge Syndrome
Familial Mediterranean fever
Job Syndrome
Common Variable Immunodeficiency
examples of secondary immunodeficiency - CORRECT ANSWER Human
Immunodeficiency Virus
Pneumocystis Carinii
Pneumonia
Sinus infection
Lung cancer
Select the best statement below that describes a primary immunodeficiency: -
CORRECT ANSWER Are less common and occur due to a defect on the
development of the immune system.
Cancer is a secondary immunodeficiency. - CORRECT ANSWER true
Sinusitis is considered a primary immunodeficiency. - CORRECT ANSWER false
A patient with human immunodeficiency virus (HIV) was admitted to the acute
care facility with difficulty breathing. He is diagnosed with Pneumocytis carinii.
Pneumocystis carinii an example of: - CORRECT ANSWER secondary immune
disease
Which of the following findings can be used to diagnose Systemic Lupus
Erythematosus (SLE)? - CORRECT ANSWER Facial rash confined to the cheeks.
A renal disease most often associated with autoimmunity is - CORRECT ANSWER
Glomerulonephritis.
The major immune system change associated with Sjogren's Syndrome is: -
CORRECT ANSWER Autoantibodies and auto-reactive T-cells against apoptotic
cells.
, Which of the following can depress a person's normal immune function? -
CORRECT ANSWER Psychological Stress
Which of the following assessment findings would support a diagnosis of
Rheumatoid Arthritis (RA)? - CORRECT ANSWER Swollen metacarpophalangeal
joints.
Which of the following statements best describes the symptoms of Systemic
Lupus Erythematosus (SLE). - CORRECT ANSWER Tissue inflammation, vasculitis,
rash, tissue inflammation.
The presence of a low number of autoantibodies is an indicator that the individual
will develop an autoimmune disease. - CORRECT ANSWER false *does not
indicate
The following immune components can be involved in autoimmune diseases: T-
Cells, B-cells and autoantibodies. - CORRECT ANSWER true
Which of the following microcytic anemias is characterized by hyperchromic
RBCs? - CORRECT ANSWER Hereditary spherocytosis.
Which of the following is NOT a clinical characteristic of anemia? - CORRECT
ANSWER bradycardia
Which of the following is considered a microcytic anemia? - CORRECT ANSWER
Iron deficiency.
Which of the following indices measures the average size of red blood cells? -
CORRECT ANSWER Mean Corpuscular Volume (MCV).
What is anemia? - CORRECT ANSWER reduction in the total number of circulating
red blood cells (RBCs) and/or a decrease in hemoglobin (Hb) amount or function
Anemia can be caused by - CORRECT ANSWER 1) impaired RBC production, 2)
excessive blood loss, 3) increased RBC destruction OR any combination of the
three.
Microcytic anemia - CORRECT ANSWER (MCV<80 fL) describes RBCs that are
small.
Examples of microcytic anemia - CORRECT ANSWER Iron deficiency
