Pharmacogenetic testing recommended in patients of Asian and SE Asian ancestry prior to initiating
which of the following?
- Imipramine
- Lamotrigine
- Fluvoxamine
- Valproic Acid
- Carbamazepine - ANSWERCarbamazepine
Dopaminergic Pathway implicated in Tardive Dyskenisia?
- Mesolimbic
- Mesocortical
- Nigrostriatal
- Tuberoinfundibular
- Incertohypothalamic - ANSWERNigrostriatal (movement)
Which hormone involved in osmoregulation, food intake, and female and sexual behaviors?
- Oxytocin
- Estrogen
- Melatonin
- Testosterone
- Progesterone - ANSWEROxytocin
Which of the following diseases is most consistent with the pedigree below?
- Wilson dz
- Phenylketonuria
- Sickle cell dz
- Huntington dz
- Cri-du-chat syndrome - ANSWERHuntington's (AD)
PTSD most commonly associated with reduced volume on MRI where?
- Thalamus
- Hippocampus
, - Hypothalamus
- Cerebral cortex
- Corpus callosum - ANSWERHippocampus
44yo pt presents with fatigue and depression. Physical exam shows darkening of skin and mucosa.
Which test will lead to dx?
- Porphobilinogen
- Vanillylmandelic acid
- TSH
- 5-hydroxyindoleacetic acid
- Adrenocorticotropic hormone simulation test - ANSWERAdrenocorticotropic hormone simulation
test (Addison's dz)
Buprenorphine is combined with naloxone in PO form to reduce which?
- Cravings
- Side effects
- Abuse potential
- Drug interactions
- Overdose lethality - ANSWERAbuse potential
Childhood trauma, which increases risk for PTSD and depression, is correlated with increase in which
gene expression?
- AKT1
- SERT
- FRM1
- ApoE2
- FKBP5 - ANSWERFKBP5 (MDD, asthma)
Most compelling argument for allowing clinicians to have unrestricted access to mental health info.
in EHR?
- Privacy rights do not apply for pts admitted involuntarily
- EHR info confidentiality is less relevant in era of big data
- Unrestricted access to psych records lowers mental illness stigma
- Social media acceptance has diminished concern for privacy/confidentiality
- Readmission rates trend lower in hospitals with unrestricted EHR access - ANSWERReadmission
rates trend lower in hospitals with unrestricted EHR access