MMSC 491 Exam 1- Questions and Answers 100% Correct

MMSC 491 Exam 1- Questions and Answers 100%
Correct

Wobble Postition Correct Ans-The third position in the triplet adn typically does not efect
whcih amino acid is formed




Silent Mutations Correct Ans-Change in 1 base of the nucleotide (typically in wobble) and
does not cause a change in the amino acid that is expressed




Nonsense Mutations Correct Ans-singluar base is changed and causes early termination in
the sequence adn now causes a "stop" codon to form




Missense Mutation Correct Ans-Changed in 1 base and causes a change in the amino acid
that is expressed

2 Types: Conservative and Nonconservative




Conservative Missense Mutation Correct Ans-Amino acid changes, but the amino acid that
is put in has similar properties/that behave similary to the original amino acid that was in
place from the biochemical stand point




Nonconservative Missense Mutation Correct Ans-The new amino acid that is placed has
different chemical properties from the original amino acid prior to mutations




Difference between Deoxyribose and Ribose Correct Ans-at the 2' psotion on the deozy
there is a hydrogen attached compared to Ribose that has an OH group

, MMSC 491 Exam 1- Questions and Answers 100%
Correct

Effects of Epigentic Alteration Correct Ans-1. Alters accessibility of DNA

2. Changes in gene Expression




Purines Correct Ans-Adenine and Guanine (has 2 rings)




Pyramidines Correct Ans-Cytosine, Thymine, and Uracil (Has 1 ring




DNA Bases Correct Ans-AGTC




RNA Bases Correct Ans-AGUC




Structure of ssDNA Correct Ans--Asymetric 5' and 3' end

-5'end = phospahate group

-3' end: Hydroxyl Group




DsDNA Correct Ans--Strands run antiparralel

-Runs 5'-3' with the oppsosite running 3'-5'




Hydrogen bonds between A &T Correct Ans-2 hydrogen Bonds

, MMSC 491 Exam 1- Questions and Answers 100%
Correct
Hydrogen bonds between G and C Correct Ans-3 hydrogen bonds




DNA Replication is Correct Ans-Semi-conservative




DNA Polymerase synthesizes in the Correct Ans-5'-3' direction




Leading strand of DNA Correct Ans-DNA is syntheiszed in a processive manner in the same
way as the replciation fork (5'-3')




Lagging Strand of DNA Correct Ans-DNA is syntheiszed in a back stitich way, by using
fragments because it is synthesized in backwards way, these fragments known as okazaki
Fragemnts




Classic DNA-Dependent Polymerase Correct Ans--Builds off the template

-Required for DNA Replication

-Alpha, delta, epsilon, Beta, and Gamma




Alpha DNA Polymerase Correct Ans-Initiates DNA syntheiss and participates in formation
of the okazawki fragments




Delta and Epsilon DNA Polymerase Correct Ans-Major DNA Polymerase that play major
role in DNA Replication and Repair

, MMSC 491 Exam 1- Questions and Answers 100%
Correct

Beta DNA Polymerase Correct Ans-Involved in DNA Repair




Gamma DNA Polymerase Correct Ans-Dedicatid to Mitochondrial DNA Repair and
Synthesis




RNA Dependent DNA Polymerases Correct Ans--Retrosposon Reverse Transcriptase

-Telomerase Reverse Transciptase




Involved in Retrosposon Reverse Transcription Correct Ans-Occasionly convert mRNA and
other RNA to cDNA that integrate into our genome that can give rise to new genes




Telomerase Reverse Transcriptase (TERT) Correct Ans--Replicates DNA at end of Linear
Chromsomes using RNA Template

-Ends of chromsomes are not replicated in DNA synthesis use seperate Process




Transcription Correct Ans--Synthesis of RNA

Messenger RNA (mRNA)

-Function end point of gene expression are RNA which include

a)tRNA

b)rRNA

c) ETC