PBSC pharm final study guide
lorazepam(Ativan) - answer benzodiazepine anxiolytic -intensifies GABA - ae: fall risk,
resp depression
phenytoin(Dilantin) - answer hydantoin for seizures- desensitizes Na channels - not for
use in elderly/pregnant causes CNS depression
chlorpromazine(thiazine) – answer phenothiazine for psychosis - blocks dopamine-
causes EPS's
haloperidol(Haldol) – answer nonpenetrative for psychosis - blocks dopamine type 2
receptor - less sedation than chlorpromazine- causes EPS's and NMS
duloxetine(Cymbalta) - answeratypical SNRI antidepressant - 4 weeks for benefits -
imipramine(tofranil) - answerTCA - inhibits reuptake of serotonin and NE -
anticholinergic for depression
phenelzine(nardil) - answerMAOI antidepressant
sertraline(Zoloft) - answersafest antidepressant - SSRI
catecholamine - answeradrenergic agonist
valproic acid - answerphenytoin for seizures-depresses Na- causes CNS depression
diazepam(valium) - answerbenzodiazepine for seizures - stimulates GABA - depressant
escitalopram oxalate (Lexapro) - answerSSRI for anxiety- depressant
zolpidem(ambien) - answerhypnotic nonbenz/nonbarb for insomnia - binds to GABA -
only used for 7-10 days - ae: sleepwalking
ethosuximide(zarontin) - answersuccinimide for seizures - lowers Ca - depressant
aripiprizole(abilify) - answerDSS antipsychotic - less EPS's
prazosin(minipress) - answersympatholytic- htn, dysrhythmias,glaucoma etc
(vasodialates)
, atropine - answeranticholinergic- reverses pesticide poisoning, dialates
pupils(mydriasis), parkinsons, asthma
PHENOBARBITAL(LUMINAL) - answerbarbiturate for seizures - stimulates GABA -
causes vitamin d+k deficiencies (bleeding/bruises), schedule IV
lithium carbonate(eskalith) - answerbipolar mood stabilizer - Na transport - causes
muscle weakness/tremors
phenylephrine9neo-synephrine) - answersympathomimetic - stimulates norepinephrine
alpha 1 treats - answernasal congestion, hypotension, mydriasis
cholinergic crisis - answernausea, rapid hr, muscle weakness, headache
cardiotonic/inotropic - answerbeta 1 adrenergics
tocolytics - answerrelax uterine muscles; beta 2 adrenergics
kappa receptors cause - answeranalgesia, decreased gi motility, miosis
parkinsons - answerdopamine dies causing ACh to buildup
levodopa(stalevo - answerdopaminergic for parkinsons - causes diskinesias
benzotropine(Cogentin) - answeranticholinergic for parkinsons
donepezil(Aricept) - answeralzheimers - AchE inhibitor(prevents ach breakdown)
diphenoxylate w/atropine(lomotil) - answeranti-diarrheal opioid
melana - answerblood in stool
ulcerative colitis, cron's disease - answerinflammatory bowel diseases
sulfasaline(azulfidine) - answerantibac/anti-inflammatory for ibd/ibs/ulcerative colitis
prochlorperazine(Compazine) - answerantiemetic-anticholinergic
omeprazole(Prilosec) - answerproton pump inhibitor to reduce acid secretions for PUD -
short term 4-8 weeks -give with antacids and clarithromycin -no smoking
ranitidine(zantac) - answerh2 receptor blocker for PUD - don't take with antacids -risk
for anemia (lowers r/w BC's with LT use)
lorazepam(Ativan) - answer benzodiazepine anxiolytic -intensifies GABA - ae: fall risk,
resp depression
phenytoin(Dilantin) - answer hydantoin for seizures- desensitizes Na channels - not for
use in elderly/pregnant causes CNS depression
chlorpromazine(thiazine) – answer phenothiazine for psychosis - blocks dopamine-
causes EPS's
haloperidol(Haldol) – answer nonpenetrative for psychosis - blocks dopamine type 2
receptor - less sedation than chlorpromazine- causes EPS's and NMS
duloxetine(Cymbalta) - answeratypical SNRI antidepressant - 4 weeks for benefits -
imipramine(tofranil) - answerTCA - inhibits reuptake of serotonin and NE -
anticholinergic for depression
phenelzine(nardil) - answerMAOI antidepressant
sertraline(Zoloft) - answersafest antidepressant - SSRI
catecholamine - answeradrenergic agonist
valproic acid - answerphenytoin for seizures-depresses Na- causes CNS depression
diazepam(valium) - answerbenzodiazepine for seizures - stimulates GABA - depressant
escitalopram oxalate (Lexapro) - answerSSRI for anxiety- depressant
zolpidem(ambien) - answerhypnotic nonbenz/nonbarb for insomnia - binds to GABA -
only used for 7-10 days - ae: sleepwalking
ethosuximide(zarontin) - answersuccinimide for seizures - lowers Ca - depressant
aripiprizole(abilify) - answerDSS antipsychotic - less EPS's
prazosin(minipress) - answersympatholytic- htn, dysrhythmias,glaucoma etc
(vasodialates)
, atropine - answeranticholinergic- reverses pesticide poisoning, dialates
pupils(mydriasis), parkinsons, asthma
PHENOBARBITAL(LUMINAL) - answerbarbiturate for seizures - stimulates GABA -
causes vitamin d+k deficiencies (bleeding/bruises), schedule IV
lithium carbonate(eskalith) - answerbipolar mood stabilizer - Na transport - causes
muscle weakness/tremors
phenylephrine9neo-synephrine) - answersympathomimetic - stimulates norepinephrine
alpha 1 treats - answernasal congestion, hypotension, mydriasis
cholinergic crisis - answernausea, rapid hr, muscle weakness, headache
cardiotonic/inotropic - answerbeta 1 adrenergics
tocolytics - answerrelax uterine muscles; beta 2 adrenergics
kappa receptors cause - answeranalgesia, decreased gi motility, miosis
parkinsons - answerdopamine dies causing ACh to buildup
levodopa(stalevo - answerdopaminergic for parkinsons - causes diskinesias
benzotropine(Cogentin) - answeranticholinergic for parkinsons
donepezil(Aricept) - answeralzheimers - AchE inhibitor(prevents ach breakdown)
diphenoxylate w/atropine(lomotil) - answeranti-diarrheal opioid
melana - answerblood in stool
ulcerative colitis, cron's disease - answerinflammatory bowel diseases
sulfasaline(azulfidine) - answerantibac/anti-inflammatory for ibd/ibs/ulcerative colitis
prochlorperazine(Compazine) - answerantiemetic-anticholinergic
omeprazole(Prilosec) - answerproton pump inhibitor to reduce acid secretions for PUD -
short term 4-8 weeks -give with antacids and clarithromycin -no smoking
ranitidine(zantac) - answerh2 receptor blocker for PUD - don't take with antacids -risk
for anemia (lowers r/w BC's with LT use)
