,ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
,ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
, ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
Chapter71,7The7Foundation7of7Pharmacology:7Quality7and7Safety
1. A7woman7diagnosed7with7obsessive–
compulsive7disorder7has7been7prescribed7oral7 paroxetine7hydrochloride.7 What7 is7t
he7expected7effect7 for7this7prescription?
A. Curative7effect7 on7symptoms
B. Systemic7effect7on7symptoms
C. Local7effect7on7symptoms
D. Parenteral7effect7on7symptoms
ANS:77B
Rationale:7Drugs7that7 produce7systemic7effects7are7taken7into7the7body,7circulated7through7 th
e7bloodstream7to7their7sites7of7action7in7various7body7tissues,7and7eventually7eliminated7 from
7the7body.7 Curative7agents7are7given7to7 cure7a7disease7process.7 In7this7case,7paroxetine7 hydr
ochloride7will7control7the7symptoms7but7 not7cure7the7disorder.7Drugs7with7local7effects,7 such7as
7sunscreen7and7 local7anesthetics,7 act7mainly7at7the7site7of7application.7 Paroxetine7 hydrochlori
de7 is7not7administered7parenterally.7Parenteral7agents7are7administered7 subcutaneously,7 intr
amuscularly,7or7intravenously.
PTS: 1 REF: p.73,7Introduction OBJ: 1
NAT:7 Client7Needs:7Physiological7Integrity:7Pharmacological7and7Parenteral7Therapies7 T
OP: Chapter:71:7The7Foundation7of7Pharmacology:7 Quality7and7Safety
KEY:7 Integrated7Process:7Nursing7Process
BLM:77 Cognitive7 Level:7Understand NOT:7 Multiple7Choice
2. A7client7 has7been7prescribed7an7antibiotic.7This7medication7is7a7naturally7occurring
substance7that7has7been7cheG mR
icA
alDlyEm
SoBdOifOieSd.TWhaOt7M
.C is7another7name7for7this7type7of7medicatio
n?
A. Synthetic7drug
B. Semisynthetic7drug
C. Biotechnology7drug
D. Prototype7drug
ANS:77B
Rationale:7Semisynthetic7drugs7(e.g.,7many7antibiotics)7are7 naturally7occurring7substances7 that
7have7been7chemically7modified.7Synthetic7drugs7are7more7standardized7 in7their7 chemical7 cha
racteristics,7 more7consistent7 in7their7effects,7and7less7likely7to7produce7allergic7reactions.7 Biote
chnology7drugs7involve7manipulating7DNA7and7RNA7and7recombining7genes7into7 hybrid7 mole
cules7that7 can7be7 inserted7into7living7organisms.7Prototype7drugs7are7the7first7 drug7of7a7partic
ular7group7to7 be7developed.
PTS: 1 REF: p.73,7Drug7Sources OBJ: 1
NAT:7 Client7Needs:7Physiological7Integrity:7Pharmacological7and7Parenteral7Therapies7 T
OP: Chapter:71:7The7Foundation7of7Pharmacology:7Quality7and7Safety
KEY:7 Integrated7Process:7Nursing7Process
BLM:77 Cognitive7 Level:7Understand NOT:7 Multiple7Choice
3. Which7classification7applies7to7morphine?
A. Central7nervous7system7depressant
B. Central7nervous7system7stimulant
ABRAMS'7CLINICAL7DRUG7THERAPY:7RATIONALES7FOR7NURSING7PRACTICE