Verified!!
T/F Chemotherapy consenting is to be performed by the patient's attending physician - ANSWERTrue
A ________ consent is required if the chemo is being used in a new way and/or a new drug is added
to the regimen. - ANSWERNew
T/F A patient can leave their shoes on when height and weight are obtained ONLY if the patient is
suffering from peripheral neuropathy. - ANSWERFalse
Who determines if actual, ideal, or adjusted body weight is to be used in chemo dosing? -
ANSWERPhysician
The Calvert formula is used to calculate the dose of what drug? - ANSWERCarboplatin
What does the AUC measure? - ANSWERArea under the curve/drug exposure
T/F Mrs. S is receiving Carboplatin dosed with an AUC of 6 and Mrs. H is receiving Carboplatin with
AUC of 2. The nurse knows Mrs. S. may have more toxicity to the drug since her AUC is higher than
Mrs. H. - ANSWERTrue
A UPMC fellow cannot write orders independently in the first _________ - ANSWER3 months
_____________ chemotherapy administered IV push should be administered at a rate of
5mL/minute and blood return should be assessed after every _____mL of drug administered. -
ANSWERVesicant, 3
T/F The most accurate method to measure creatinine clearance is to collect urine for 24 hours to
measure level - ANSWERTrue
T/F When administering an IV push med, the nurse should open the clamp of compatible IV solution
until increased flow is seen to dilute the agent during administration. - ANSWERTrue
During the 2 RN check, the correct patient and dose is to be verified at the ______ -
ANSWERbedside/chairside
Continuous infusion of vesicants must be through a ________ - ANSWERcentral line
Excretion safety precautions last for ____ to _____ days. - ANSWER3-7
T/F When evaluating a patient prior to chemo, the nurse notes the patient recently had weight loss.
The nurse recalculates the dose and discovers a change in the dose greater than 10%. The next step
for the nurse is to notify the attending physician that the patient will need re-consented because of
the dose adjustment - ANSWERFalse
Alkylating agents are cell cycle non-specific. They work on _____ and resting cells. - ANSWERdividing
Alkylating agents are effective in slow growing tumors and large tumors that have few actively
________ - ANSWERdividing cells
, List 3 toxicities common in all alkylating agents - ANSWERNausea, vomiting, myelosuppression,
infertility, hypersensitivity reactions, alopecia, secondary malignancies, tumor lysis synndrome,
pregnance category D
Which class of drugs can cross the blood brain barrier, increasing a patient's risk for CNS toxicities -
ANSWERnitrosureas
The solvent for carmustine (BCNU) - ANSWERSterile alcohol
The ________ formula is used to calculate Carboplatin dosage - ANSWERCalvert
T/F Temozalamide (Temodor) effectively crosses the blood brain barrier - ANSWERTrue
patients may feel intoxicated during the administration of ______ - ANSWERCarmustine (BCNU)
Patients are prophylictically medicated with anticonvulsants before receiving _________ and 24
hours after the last dose to prevent seizures - ANSWERBusulfan
T/F Oxaliplatin should only be mixed with D5W - ANSWERTrue
Which drug should ALWAYS be given with Mesna - ANSWERIfosfamide
Pulmonary fibrosis is a late complication of patients who receive ________ - ANSWERBusulfan
The platinum alkylating agents include ______, ______, and _______. - ANSWERCisplatin,
Carboplatin, and Oxaliplatin
Cisplatin (Platinol) is a _________ emetogenic drug. - ANSWERhighly
Pretreatment hydration is administered to prevent this toxicity of cisplatin - ANSWERNephrotoxicity
T/F Cisplatin (Platinol) should be administered before paclitaxel (Taxol) to prevent delayed paclitaxel
excretion and increased toxicity. - ANSWERFalse
T/F Electrolyte levels need to be closely monitored and often supplemented for cisplatin (platinol) -
ANSWERTrue
The more treatments a patient receives _______ the risk for reaction with carboplatin (paraplatin). -
ANSWERIncreases
A dose limiting adverse effect associated with oxaliplatin (eloxatin) is ________. -
ANSWERNeurotoxicity
Patients should avoid cold fluids for 5 days after receiving _______ to help prevent _________. -
ANSWEROxaliplatin, acute neurotoxcity
Common side effects of antimetabolites - ANSWERmyelosuppression, mucositis, GI Symptoms, Liver
dysfunction
Leucovorin rescue beings ______ after the end of the methotrexate infusion - ANSWER24 hours
T/F High doses of methotrexate should not be administered to patients with abnormal renal function
- ANSWERTrue
When receiving pemetrexed (Alimta) patients are pretreated with _______ and _______ to decrease
toxicity of the drug - ANSWERVitamin B12 and Folic Acid