NSG 530 EXAM 1
Hypersensitivity is best defined as a(an):
Altered immunologic response to an antigen that results in disease
A hypersensitivity reaction that produces an allergic response is called:
Anaphylaxis
The common hay fever allergy is expressed through a reaction that is mediated by
which class of immunoglobulins?
IgE
Which type of antibody is involved in type I hypersensitivity reaction?
IgE
Blood transfusion reactions are an example of:
Allo-immunity
During an IgE-mediated hypersensitivity reaction, which leukocyte is activated?
Eosinophils
During an IgE-mediated hypersensitivity reaction, what causes bronchospasm?
Smooth muscle contraction caused by histamine bound to H1 receptors
, During an IgE-mediated hypersensitivity reaction, the degranulation of mast cells is a
result of which receptor action?
Histamine bound to H2
What characteristic do atopic individuals have that make them genetically
predisposed to develop allergies?
Greater quantities of IgE
What is the mechanism that results in type II hypersensitivity reactions?
Antibodies bind to the antigens on the cell surface.
When mismatched blood is administered causing an ABO incompatibility, the
erythrocytes are destroyed by:
Complement- mediated cell lysis
When antibodies are formed against red blood cell antigens of the Rh system, the
blood cells are destroyed by:
Phagocytosis in the spleen
When soluble antigens from infectious agents enter circulation, tissue damage is a
result of:
Neutrophil granules and toxic oxygen products
How are target cells destroyed in a type II hypersensitivity reaction?
Natural killer cells
Hypersensitivity is best defined as a(an):
Altered immunologic response to an antigen that results in disease
A hypersensitivity reaction that produces an allergic response is called:
Anaphylaxis
The common hay fever allergy is expressed through a reaction that is mediated by
which class of immunoglobulins?
IgE
Which type of antibody is involved in type I hypersensitivity reaction?
IgE
Blood transfusion reactions are an example of:
Allo-immunity
During an IgE-mediated hypersensitivity reaction, which leukocyte is activated?
Eosinophils
During an IgE-mediated hypersensitivity reaction, what causes bronchospasm?
Smooth muscle contraction caused by histamine bound to H1 receptors
, During an IgE-mediated hypersensitivity reaction, the degranulation of mast cells is a
result of which receptor action?
Histamine bound to H2
What characteristic do atopic individuals have that make them genetically
predisposed to develop allergies?
Greater quantities of IgE
What is the mechanism that results in type II hypersensitivity reactions?
Antibodies bind to the antigens on the cell surface.
When mismatched blood is administered causing an ABO incompatibility, the
erythrocytes are destroyed by:
Complement- mediated cell lysis
When antibodies are formed against red blood cell antigens of the Rh system, the
blood cells are destroyed by:
Phagocytosis in the spleen
When soluble antigens from infectious agents enter circulation, tissue damage is a
result of:
Neutrophil granules and toxic oxygen products
How are target cells destroyed in a type II hypersensitivity reaction?
Natural killer cells
