Questions and CORRECT Answers
Where does hematopoiesis occur in a fetus? - CORRECT ANSWER✔✔- It starts in the yolk
sac, then liver, spleen, then bone marrow at approximately 6 months after conception
What is the order of immature to mature segmented neutrophils? - CORRECT
ANSWER✔✔- myeloblast, promyelocyte, myelocyte, metamyelocyte, band, seg
What is the order of heme precursors? - CORRECT ANSWER✔✔- while in the DELTA,
POUR YOUR COP, PRONTO, a cup of HEME.
DELTA-aminolevulinic acid
PORphobilinogen
URoporphyrinogen
COPorphyrinogen
PROTOporphyrin
HEME
What causes porphyria? - CORRECT ANSWER✔✔- excessive formation of porphyrins due
to a step in the heme synthesis being blocked
What hemoglobin chains make embryonic hemoglobin? - CORRECT ANSWER✔✔- 2 alpha,
2 epsilon
What hemoglobin chains make Hgb F? - CORRECT ANSWER✔✔- 2 alpha, 2 gamma
What hemoglobin chains make Hgb A2? - CORRECT ANSWER✔✔- 2 alpha, 2 delta
What hemoglobin chains make Hgb A? - CORRECT ANSWER✔✔- 2 alpha, 2 beta
, What chromosomes house genetic material for hemoglobin? - CORRECT ANSWER✔✔-
Chromosome 16 (alpha and zeta)
Chromosome 11 (epsilon, gamma, delta, beta)
Under what conditions does hemoglobin release oxygen more easily? - CORRECT
ANSWER✔✔- CADET face right (causes right shift in dissociation curve)
increased
Carbon dioxide
Acid (decreased pH)
2,3 DPG
Exercise
Temperature
What hemoglobin is consider a high affinity hemoglobin? - CORRECT ANSWER✔✔-
Hemoglobin F
What are sources of error in hemoglobin levels from an analyzer? - CORRECT
ANSWER✔✔- lipemia
high wbc
resistant hgb (SS or CC)
excess hemolysis
What is the reference range for hemoglobin in males? - CORRECT ANSWER✔✔- 16+/-2
g/dL
What is the reference range for hemoglobin in females? - CORRECT ANSWER✔✔- 14+/- 2
g/dL
Caroxyhemoglobin is associated with what? - CORRECT ANSWER✔✔- CO poisoning,
causes blood to be cherry red