Pathophysiology
FA READINESS EXAM
Q&S
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,1. Which of the following is a key feature of metabolic
syndrome?
a) Elevated HDL cholesterol
b) Abdominal obesity
c) Low blood pressure
d) Increased glucose excretion
Answer: b) Abdominal obesity
Rationale: Metabolic syndrome is characterized by the
presence of abdominal obesity, dyslipidemia, hypertension,
and insulin resistance.
2. In acute respiratory distress syndrome (ARDS), which of
the following physiological changes occurs?
a) Increased lung compliance
b) Decreased pulmonary capillary permeability
c) Impaired gas exchange
d) Increased tidal volume
Answer: c) Impaired gas exchange
Rationale: ARDS leads to severe impairment in gas
exchange due to pulmonary edema and atelectasis.
3. Which condition is primarily associated with the
destruction of myelin in the central nervous system?
a) Guillain-Barré Syndrome
b) Multiple Sclerosis
c) Amyotrophic Lateral Sclerosis
d) Parkinson's Disease
Answer: b) Multiple Sclerosis
Rationale: Multiple sclerosis is characterized by the
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, autoimmune destruction of myelin sheaths in the CNS.
4. In which of the following conditions would you expect to
find elevated levels of creatinine?
a) Hepatic failure
b) Acute kidney injury
c) Congestive heart failure
d) Hyperthyroidism
Answer: b) Acute kidney injury
Rationale: Elevated creatinine levels are an indicator of
impaired renal function.
5. Which of the following is NOT a typical characteristic of
systemic lupus erythematosus (SLE)?
a) Butterfly rash
b) Increased risk of thromboembolism
c) High levels of IgM antibodies
d) Renal involvement
Answer: c) High levels of IgM antibodies
Rationale: SLE is characterized by an increase in various
autoantibodies, including anti-dsDNA, rather than just IgM
antibodies.
### Fill-in-the-Blank Questions
6. The primary mechanism of action in the neuromuscular
junction for myasthenia gravis is the _______ of
acetylcholine receptors.
Answer: destruction
Rationale: Myasthenia gravis involves the autoimmune
destruction of acetylcholine receptors, resulting in muscle
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