Quizzes
Which hepatitis virus is dependent upon the presence of the Hepatitis B virus? ANS Hepatitis D virus
What method is currently being used in the detection of HIV infection in humans? ANS Enzyme
immunoassay
What is known to cause meningoencephalitis as a human, avian and equine neuropathogenic? ANS West
Nile virus
An ABO HDFN in a group B infant group of a group O mother is more commonly found in which population?
ANS African American
The detection of fetal red blood cells containing Hgb F is shown as _____ in the Kleibauer-Betke test. ANS
Pink
What type of transfusion is used to prevent kernicterus? ANS Exchange transfusion
During 10-12 weeks gestation, what can be used to test for the presence of the D antigen in the fetus? ANS
Fetal DNA testing
Cold AIHA is sometimes associated with infection in: ANS Mycoplasma pneumoniae
Immune hemolytic anemias may be classified in what categories? ANS Alloimmune, autoimmune, and
drug-induced
When penicillin is involved, which of the classic mechanisms is typically involved in the hemolytic process?
ANS Drug-adsorption
What is the confirmation test for HIV? ANS Western Blot
, Which marker is usually not detected when the hepatitis B-infected patients enters the convalescent (recovery)
phase? ANS HBeAg
What characterizes hemolytic disease of the newborn (HDFN)? ANS Destruction of the fetus' RBCs by
antibodies produced by the mother
What effect does ABO incompatibility between the mother and the fetus have on maternal sensitization to Rh
antigen? ANS The chance of maternal sensitization to Rh antigen is decreased.
Severe anemia, effusions, and ascites from hepatomegaly and splenomegaly: ANS Hydrops fetalis
Characteristics of benign cold autoantibodies: ANS -Encountered during testing performed at 4C
-IgM and can activate complement in vitro
-Normally presents no serologic problem
-Occasionally are clinically significant and may cause immune hemolytic anemia
Immune hemolytic anemia (IHA) is defined as: ANS A shortened RBC survival mediated through humoral
antibody production
What describes the drug-adsorption (Hapten) mechanism? ANS Drugs bind firmly to proteins of the RBC
membrane
Characteristics of hemolytic disease of the fetus and newborn (HDFN): ANS -Caused by IgG antibodies
that cross the placenta
-Incidence of HDFN has decreased with introduction of RhIG
-95% of cases caused by maternally produced anti-D
-Mother stimulated to form Abs by previous pregnancy or transfusion
True or false: HDFN is the destruction of the RBCs of a fetus an d neonate by antibodies produced by the
father. ANS False
Some techniques used in the diagnosis and treatment of HDFN: ANS -Ultrasonography