AHN554 Module 4 Hematology Part 1
Study Guide With Solution
Subjective findings seen in anemia:
SOB
Tachycardia
Irregular heartbeat
Fatigue
Lightheadedness
Dizziness
Headache
Decreased exercise tolerance
RBCs value normal
Male: 4.7 to 6.1 mil/mcL)
Female: 4.2 to 5.4 mil/mcL
normal Hgb and Hct levels
Normal Male Hgb 14-18 g/dL; Hct 40-54%
Normal Female Hgb 12-16 g/dL; Hct 37-48%
,MCV (Mean Corpuscular Volume definition
this is the average size of the blood cell-RBC- in this case)
MCV values for micro/macrocytic anemias
< 80 fL (small cell) --> MICROcytic
80-100 fL (normal sized cell) -->NORMOcytic
> 100 fL (abnormally large cell)--> MACROcytic
MCHC (Mean Cell Hemoglobin Concentration) definition
this is the average Hgb concentration in RBCs
MCHC (Mean Cell Hemoglobin Concentration) values
> 30 g/dL (normal color) --> NORMOCHROMIC
< 30 g/dL (pale color) -->HYPOCHROMIC
RDW (Red Cell Distribution Width definition
This is the degree of size variation among circulating RBCs
RDW (Red Cell Distribution Width values
< 15% -->Normal (i.e. not a lot of variation)
> 15% --> Early indication that new cells are abnormal (microcytic or
, macrocytic) (i.e. higher than normal variation)
Reticulocyte Count definition
This the Measure of the proportion of immature RBCs in the blood
Reticulocyte Count values
1-2%--> Normal
> 2% indicates that body's normal response to anemia (reticulocytosis)
Vitamin B12 (Cobalamin) levels:
> 300 pg/mL --> Normal
200-300 pg/mL --> Borderline
< 200 pg/mL --> Vitamin B12 deficiency
importance of Vitamin B12 and folate (B9) synthesis
important for DNA synthesis for TBCs
Folate (B-9) levels:
> 4 ng/mL --> Normal
2 to 4 ng/mL-->Borderline
< 2 ng/mL -->Folate deficiency
Study Guide With Solution
Subjective findings seen in anemia:
SOB
Tachycardia
Irregular heartbeat
Fatigue
Lightheadedness
Dizziness
Headache
Decreased exercise tolerance
RBCs value normal
Male: 4.7 to 6.1 mil/mcL)
Female: 4.2 to 5.4 mil/mcL
normal Hgb and Hct levels
Normal Male Hgb 14-18 g/dL; Hct 40-54%
Normal Female Hgb 12-16 g/dL; Hct 37-48%
,MCV (Mean Corpuscular Volume definition
this is the average size of the blood cell-RBC- in this case)
MCV values for micro/macrocytic anemias
< 80 fL (small cell) --> MICROcytic
80-100 fL (normal sized cell) -->NORMOcytic
> 100 fL (abnormally large cell)--> MACROcytic
MCHC (Mean Cell Hemoglobin Concentration) definition
this is the average Hgb concentration in RBCs
MCHC (Mean Cell Hemoglobin Concentration) values
> 30 g/dL (normal color) --> NORMOCHROMIC
< 30 g/dL (pale color) -->HYPOCHROMIC
RDW (Red Cell Distribution Width definition
This is the degree of size variation among circulating RBCs
RDW (Red Cell Distribution Width values
< 15% -->Normal (i.e. not a lot of variation)
> 15% --> Early indication that new cells are abnormal (microcytic or
, macrocytic) (i.e. higher than normal variation)
Reticulocyte Count definition
This the Measure of the proportion of immature RBCs in the blood
Reticulocyte Count values
1-2%--> Normal
> 2% indicates that body's normal response to anemia (reticulocytosis)
Vitamin B12 (Cobalamin) levels:
> 300 pg/mL --> Normal
200-300 pg/mL --> Borderline
< 200 pg/mL --> Vitamin B12 deficiency
importance of Vitamin B12 and folate (B9) synthesis
important for DNA synthesis for TBCs
Folate (B-9) levels:
> 4 ng/mL --> Normal
2 to 4 ng/mL-->Borderline
< 2 ng/mL -->Folate deficiency
