AHN554 Module 4 Hematology Part 1 Study Guide With Solution

AHN554 Module 4 Hematology Part 1
Study Guide With Solution


Subjective findings seen in anemia:

SOB

Tachycardia

Irregular heartbeat

Fatigue

Lightheadedness

Dizziness

Headache

Decreased exercise tolerance




RBCs value normal

Male: 4.7 to 6.1 mil/mcL)

Female: 4.2 to 5.4 mil/mcL

normal Hgb and Hct levels

Normal Male Hgb 14-18 g/dL; Hct 40-54%

Normal Female Hgb 12-16 g/dL; Hct 37-48%

,MCV (Mean Corpuscular Volume definition

this is the average size of the blood cell-RBC- in this case)

MCV values for micro/macrocytic anemias

< 80 fL (small cell) --> MICROcytic

80-100 fL (normal sized cell) -->NORMOcytic

> 100 fL (abnormally large cell)--> MACROcytic




MCHC (Mean Cell Hemoglobin Concentration) definition

this is the average Hgb concentration in RBCs




MCHC (Mean Cell Hemoglobin Concentration) values

> 30 g/dL (normal color) --> NORMOCHROMIC

< 30 g/dL (pale color) -->HYPOCHROMIC




RDW (Red Cell Distribution Width definition

This is the degree of size variation among circulating RBCs




RDW (Red Cell Distribution Width values

< 15% -->Normal (i.e. not a lot of variation)

> 15% --> Early indication that new cells are abnormal (microcytic or

, macrocytic) (i.e. higher than normal variation)




Reticulocyte Count definition

This the Measure of the proportion of immature RBCs in the blood




Reticulocyte Count values

1-2%--> Normal

> 2% indicates that body's normal response to anemia (reticulocytosis)




Vitamin B12 (Cobalamin) levels:

> 300 pg/mL --> Normal

200-300 pg/mL --> Borderline

< 200 pg/mL --> Vitamin B12 deficiency

importance of Vitamin B12 and folate (B9) synthesis

important for DNA synthesis for TBCs




Folate (B-9) levels:

> 4 ng/mL --> Normal

2 to 4 ng/mL-->Borderline

< 2 ng/mL -->Folate deficiency