Quality Control (BLUE) UPDATED Actual
Exam Questions and CORRECT Answers
A buret with a glass stopcock can be used for:
A. Alcohols C. Acids
B. Bases D. Salts - CORRECT ANSWER- ✔✔C
The operation speed for paddle in a dissolution apparatus is:
A.150 rpm C.100 rpm
B. 200 rpm D. 50 rpm - CORRECT ANSWER- ✔✔D
Radiant energy refers to:
A. Visible C. UV
B. IR D. All of the above - CORRECT ANSWER- ✔✔D
High pressure liquid chromatography method of analysis is more advantageous than the other
column chromatography as to:
A. Ease to operate C. More precise
B. Greater speed D. All of the above - CORRECT ANSWER- ✔✔D
Content uniformity test is to be performed for all tablet products whose active ingredient is:
A. 50 mg or smaller C. 130-324 mg
B. 324 mg or more D. 130 mg or less - CORRECT ANSWER- ✔✔A
The statement of expiration date assures the patient:
A. Absence of toxicity C. Complete absorption of drug
B. Full therapeutic efficacy D. Absence of interaction - CORRECT ANSWER- ✔✔B
A factor obtained by taking the ratio of the actual normality to the theoretical normality is:
A. Titer C. Flame photometer
,B. Normality factor D. Polarimeter - CORRECT ANSWER- ✔✔B
To measure the optical activity of a sample, the instrument used is:
A. Spectrometer C. Flame photometer
B. Refractometer D. Polarimeter - CORRECT ANSWER- ✔✔D
In phenol content determination of a volatile oil, the layer in the graduated neck of the cassia
flask read 2.7 ml obtained from a sample of 10 ml of the oil after treatment of KOH. The %
phenol is:
A. 69.8 C. 73.0
B. 27.0 D. 7.30 - CORRECT ANSWER- ✔✔C
Using the Karl Fischer method, determine the moisture content of a sample of raw material
where a 63 mg sample consumed 0.75 ml of titrant. Water equivalence factor is 1.10.
A. 1.8% C. 2.10%
B. 1.3% D. 0.74% - CORRECT ANSWER- ✔✔B
During shipment of the finished product to the wholesale or retail outlets, the responsible
person
should ensure:
A. Product identification C. Segregation of different types
B. No damage, spillage or breakage D. All of the above - CORRECT ANSWER- ✔✔D
To find the mEq factor of an oxidizing agent is to divide the molecular weight by:
A. Valence C. No. of electrons gained (VDGEROA)
B. No. of electron lost D. Replaceable hydrogen - CORRECT ANSWER- ✔✔C
Lower control limit if mean is 10.5 ml and one standard deviation is 0.025.
A. 10.450 ml C. 10.575 ml
B. 10.420 ml D. 10.425 ml - CORRECT ANSWER- ✔✔D
,Gas chromatography is utilized in the separation and identification of:
A. Amino acid C. Volatile liquids in a mixture
B. Alkaloids D. Blood components - CORRECT ANSWER- ✔✔C
The name of the originator of using silver nitrate as the titrant and potassium chromate as the
indicator in volumetric precipitation of chloride.
A. Volhard C. Mohr
B. Beer D. Fajan - CORRECT ANSWER- ✔✔C
Reassay date of thiamine Hcl if tested in December 1992.
A. 6/93 C. 12/94
B. 12/93 D. 6/94 - CORRECT ANSWER- ✔✔B
Find the acid number of a raw material a mole weighing 1.230 g which required 30 ml of
0.1100 N NaOH to bring out the end point using alcoholic KOH in the titration.
A. 150.54 mg/g C. 109.18 mg/g
B. 157.72 mg/g D. 124.41 mg/g - CORRECT ANSWER- ✔✔A
A critical defect that would stop the packaging operation is:
A. Misaligned label C. Smeared label
B. Wrong label D. Inverted label - CORRECT ANSWER- ✔✔B
An instrument use to measure the durability of tablets to shipping/transportation against
shock
and abrasion.
A. Metal detector C. Friabilator
B. Top loading balance D. Colorimeter - CORRECT ANSWER- ✔✔C
Methods of microbial assay of antibiotics:
, A. Turbidimetric C. Both A and B
B. Cylinder plate D. None of the above - CORRECT ANSWER- ✔✔A
Retention or preservation of samples and records of all pharmaceutical products should be
monitored for signs of deterioration. The length of time they should be stored is:
A. 2 years after date of expiration C. 2 years
B. 1 year after date of expiration D. 3 years - CORRECT ANSWER- ✔✔B
Potentiometry finds application in:
A. Biological assay C. Qualitative analysis
B. Identification test D. pH determination - CORRECT ANSWER- ✔✔D
In the assay of sulfonamides, the method used is:
A. Diazotization C. Gravimetric
B. Acid-base titration D. Volumetric - CORRECT ANSWER- ✔✔A
A term in compleximetry used to indicate a determination of a metal in the presence of
another
metal.
A. Linking C. Complexing
B. Masking D. Redox - CORRECT ANSWER- ✔✔B
cGMP is:
A. An agency created by RA 3720
B. Also known as Food, Drug and Cosmetic Act
C. Both A and B are correct
D. Both A and B are incorrect - CORRECT ANSWER- ✔✔D
The sampling and examination of all raw materials received by the factory is a function of
the:
Exam Questions and CORRECT Answers
A buret with a glass stopcock can be used for:
A. Alcohols C. Acids
B. Bases D. Salts - CORRECT ANSWER- ✔✔C
The operation speed for paddle in a dissolution apparatus is:
A.150 rpm C.100 rpm
B. 200 rpm D. 50 rpm - CORRECT ANSWER- ✔✔D
Radiant energy refers to:
A. Visible C. UV
B. IR D. All of the above - CORRECT ANSWER- ✔✔D
High pressure liquid chromatography method of analysis is more advantageous than the other
column chromatography as to:
A. Ease to operate C. More precise
B. Greater speed D. All of the above - CORRECT ANSWER- ✔✔D
Content uniformity test is to be performed for all tablet products whose active ingredient is:
A. 50 mg or smaller C. 130-324 mg
B. 324 mg or more D. 130 mg or less - CORRECT ANSWER- ✔✔A
The statement of expiration date assures the patient:
A. Absence of toxicity C. Complete absorption of drug
B. Full therapeutic efficacy D. Absence of interaction - CORRECT ANSWER- ✔✔B
A factor obtained by taking the ratio of the actual normality to the theoretical normality is:
A. Titer C. Flame photometer
,B. Normality factor D. Polarimeter - CORRECT ANSWER- ✔✔B
To measure the optical activity of a sample, the instrument used is:
A. Spectrometer C. Flame photometer
B. Refractometer D. Polarimeter - CORRECT ANSWER- ✔✔D
In phenol content determination of a volatile oil, the layer in the graduated neck of the cassia
flask read 2.7 ml obtained from a sample of 10 ml of the oil after treatment of KOH. The %
phenol is:
A. 69.8 C. 73.0
B. 27.0 D. 7.30 - CORRECT ANSWER- ✔✔C
Using the Karl Fischer method, determine the moisture content of a sample of raw material
where a 63 mg sample consumed 0.75 ml of titrant. Water equivalence factor is 1.10.
A. 1.8% C. 2.10%
B. 1.3% D. 0.74% - CORRECT ANSWER- ✔✔B
During shipment of the finished product to the wholesale or retail outlets, the responsible
person
should ensure:
A. Product identification C. Segregation of different types
B. No damage, spillage or breakage D. All of the above - CORRECT ANSWER- ✔✔D
To find the mEq factor of an oxidizing agent is to divide the molecular weight by:
A. Valence C. No. of electrons gained (VDGEROA)
B. No. of electron lost D. Replaceable hydrogen - CORRECT ANSWER- ✔✔C
Lower control limit if mean is 10.5 ml and one standard deviation is 0.025.
A. 10.450 ml C. 10.575 ml
B. 10.420 ml D. 10.425 ml - CORRECT ANSWER- ✔✔D
,Gas chromatography is utilized in the separation and identification of:
A. Amino acid C. Volatile liquids in a mixture
B. Alkaloids D. Blood components - CORRECT ANSWER- ✔✔C
The name of the originator of using silver nitrate as the titrant and potassium chromate as the
indicator in volumetric precipitation of chloride.
A. Volhard C. Mohr
B. Beer D. Fajan - CORRECT ANSWER- ✔✔C
Reassay date of thiamine Hcl if tested in December 1992.
A. 6/93 C. 12/94
B. 12/93 D. 6/94 - CORRECT ANSWER- ✔✔B
Find the acid number of a raw material a mole weighing 1.230 g which required 30 ml of
0.1100 N NaOH to bring out the end point using alcoholic KOH in the titration.
A. 150.54 mg/g C. 109.18 mg/g
B. 157.72 mg/g D. 124.41 mg/g - CORRECT ANSWER- ✔✔A
A critical defect that would stop the packaging operation is:
A. Misaligned label C. Smeared label
B. Wrong label D. Inverted label - CORRECT ANSWER- ✔✔B
An instrument use to measure the durability of tablets to shipping/transportation against
shock
and abrasion.
A. Metal detector C. Friabilator
B. Top loading balance D. Colorimeter - CORRECT ANSWER- ✔✔C
Methods of microbial assay of antibiotics:
, A. Turbidimetric C. Both A and B
B. Cylinder plate D. None of the above - CORRECT ANSWER- ✔✔A
Retention or preservation of samples and records of all pharmaceutical products should be
monitored for signs of deterioration. The length of time they should be stored is:
A. 2 years after date of expiration C. 2 years
B. 1 year after date of expiration D. 3 years - CORRECT ANSWER- ✔✔B
Potentiometry finds application in:
A. Biological assay C. Qualitative analysis
B. Identification test D. pH determination - CORRECT ANSWER- ✔✔D
In the assay of sulfonamides, the method used is:
A. Diazotization C. Gravimetric
B. Acid-base titration D. Volumetric - CORRECT ANSWER- ✔✔A
A term in compleximetry used to indicate a determination of a metal in the presence of
another
metal.
A. Linking C. Complexing
B. Masking D. Redox - CORRECT ANSWER- ✔✔B
cGMP is:
A. An agency created by RA 3720
B. Also known as Food, Drug and Cosmetic Act
C. Both A and B are correct
D. Both A and B are incorrect - CORRECT ANSWER- ✔✔D
The sampling and examination of all raw materials received by the factory is a function of
the:
