DPR Final Exam
1. Which type of learning results from repeated harmless stimulation of the mantle in
Aplysia?
a. Long term potentiation
b. Sensitization
c. Post tetanic potentiation
d. Habituation - ✔️✔️Habituation
1. Which of the following are important for the activation of protein Kinase A (PKA)
a. Gq/11 GPCR
b. Phospholipase C (PLC)
c. Phosphatidyl serine
d. Diacyl glycerol
e. All of these
f. None of these - ✔️✔️None of these
1. Which of the following is important for increased neurotransmitter release from the
siphon sensory neuron of aplysia in response to sensitization?
a. Increased action potential frequency
b. Action potential broadening
c. None of these
d. Increased action potential intensity - ✔️✔️Action potential broadening
1. Regarding classical conditioning inaplysia, what is the coincidence detector
a. Calmodulin
b. PKC
c. PKA
d. Adenylyl cyclase - ✔️✔️Adenylyl cyclase
1. How does sensitization differ from classical conditioning
a. Sensitization requires calmodulin activation
b. Classical conditioning relies on calmodulin activation
c. Sensitization doesn't require PKC activation
d. Classical conditioning doesn't rely on PKA activation - ✔️✔️Classical conditioning
relies on calmodulin activation
1. Regarding the binomial distribution as it relates to neurotransmitter release. What
variable changes in response to sensitization
a. X
b. N
c. Q
, d. P - ✔️✔️N
1. Regarding sensitization in aplysia, which of the following could result in increased
neurotransmitter release?
a. Phosphorylating NMDA receptiors
b. Phosphorylating AMPA receptors
c. Phosphorylating sodium channels
d. Phosphorylating potassium channels - ✔️✔️Phosphorylating potassium channels
1. The Gs and Gq/11 pathways cause what changes to the post synaptic cell
a. Decreased neurotransmitter release
b. Siphon withdrawal
c. No change
d. Increased neurotransmitter release - ✔️✔️Increased neurotransmitter release
1. cAMP is produced by which enzyme
a. adenylyl cyclase
b. PLC
c. L-type Calcium channels
d. PKA - ✔️✔️adenylyl cyclase
1. The facilitating interneuron in aplysia leads to the activation of an enzyme that
converts ATP
a. Cyclic AMP
b. Calmodulin
c. ADP
d. Adenosine triphosphate - ✔️✔️Cyclic AMP
1. Which of the following enzymes is activated by the Gq/11 GPCR?
a. PKA
b. PLC
c. Adenylyl cyclase
d. Calmodulin - ✔️✔️PLC
1. Which of the following enzymes is activated in the post synaptic cell when the
facilitating interneuron activates it?
a. FYN
b. PKG
c. Calcmodulin
d. PKA - ✔️✔️PKA
1. The facilitating interneuron releases neurotransmitter onto which receptors present
on the post synaptic membrane
a. AMPA receptors
1. Which type of learning results from repeated harmless stimulation of the mantle in
Aplysia?
a. Long term potentiation
b. Sensitization
c. Post tetanic potentiation
d. Habituation - ✔️✔️Habituation
1. Which of the following are important for the activation of protein Kinase A (PKA)
a. Gq/11 GPCR
b. Phospholipase C (PLC)
c. Phosphatidyl serine
d. Diacyl glycerol
e. All of these
f. None of these - ✔️✔️None of these
1. Which of the following is important for increased neurotransmitter release from the
siphon sensory neuron of aplysia in response to sensitization?
a. Increased action potential frequency
b. Action potential broadening
c. None of these
d. Increased action potential intensity - ✔️✔️Action potential broadening
1. Regarding classical conditioning inaplysia, what is the coincidence detector
a. Calmodulin
b. PKC
c. PKA
d. Adenylyl cyclase - ✔️✔️Adenylyl cyclase
1. How does sensitization differ from classical conditioning
a. Sensitization requires calmodulin activation
b. Classical conditioning relies on calmodulin activation
c. Sensitization doesn't require PKC activation
d. Classical conditioning doesn't rely on PKA activation - ✔️✔️Classical conditioning
relies on calmodulin activation
1. Regarding the binomial distribution as it relates to neurotransmitter release. What
variable changes in response to sensitization
a. X
b. N
c. Q
, d. P - ✔️✔️N
1. Regarding sensitization in aplysia, which of the following could result in increased
neurotransmitter release?
a. Phosphorylating NMDA receptiors
b. Phosphorylating AMPA receptors
c. Phosphorylating sodium channels
d. Phosphorylating potassium channels - ✔️✔️Phosphorylating potassium channels
1. The Gs and Gq/11 pathways cause what changes to the post synaptic cell
a. Decreased neurotransmitter release
b. Siphon withdrawal
c. No change
d. Increased neurotransmitter release - ✔️✔️Increased neurotransmitter release
1. cAMP is produced by which enzyme
a. adenylyl cyclase
b. PLC
c. L-type Calcium channels
d. PKA - ✔️✔️adenylyl cyclase
1. The facilitating interneuron in aplysia leads to the activation of an enzyme that
converts ATP
a. Cyclic AMP
b. Calmodulin
c. ADP
d. Adenosine triphosphate - ✔️✔️Cyclic AMP
1. Which of the following enzymes is activated by the Gq/11 GPCR?
a. PKA
b. PLC
c. Adenylyl cyclase
d. Calmodulin - ✔️✔️PLC
1. Which of the following enzymes is activated in the post synaptic cell when the
facilitating interneuron activates it?
a. FYN
b. PKG
c. Calcmodulin
d. PKA - ✔️✔️PKA
1. The facilitating interneuron releases neurotransmitter onto which receptors present
on the post synaptic membrane
a. AMPA receptors
