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Nester Microbiology - Respiratory System
Infections Exam Questions With Correct
Answers
Red throat with patches of pus and scattered tiny hemorrhages (not adenovirus) - answer✔Strep
Throat
Neck lymph nodes enlarged and tender (not adenovirus) - answer✔Strep Throat
Scarlet fever and roughening of the skin - answer✔Strep Throat
Many virulence factors that can alter structural components of the host or be enzymes and toxins
- answer✔Streptococcus pyogenes
80 subtypes of streptococcal protein that are adhesins and prevent phagocytosis due to C3b -
answer✔M protein
Streptococcal protein that helps in attachment to cells of the throat by adhering to fibrin -
answer✔Protein F
Produces DNase, hyaluronidase, and proteases to spread (does not cause conjunctivitis) -
answer✔Streptococcus pyogenes
Produces streptokinase to break clots - answer✔Streptococcus pyogenes
Produces protein G as an Fc receptor - answer✔Streptococcus pyogenes
Produces C5a peptidase, preventing migration of phagocytes - answer✔Streptococcus pyogenes
Produces Streploysins O and S that destroy erythrocytes and leukocytes -
answer✔Streptococcus pyogenes
Produces SPEs, aka erythrogenic toxin, in lysogenized form, superantigens that cause massive
release of cytokines causing scarlet fever and roughening of the skin - answer✔Streptococcus
pyogenes
Respiratory pathogen that may also cause "flesh eating necrotizing fasciitis" -
answer✔Streptococcus pyogenes
, ©THEBRIGHTSTARS 2024
Protein that prevents migration of phagocytes - answer✔C5a peptidase
Streptococcal protein that acts as an Fc receptor - answer✔Protein G
Protein produced to break clots - answer✔Streptokinase
Proteins that destroy erythrocytes and leukocytes - answer✔Streploysins O and S
Superantigens that cause massive release of cytokines causing scarlet fever and roughening of
the skin - answer✔SPE
GAS - answer✔Group A Streptococcus
Criterion for Lancefield grouping - answer✔Cell wall carbohydrates
Produces a hyaluronic acid capsule - answer✔Streptococcus pyogenes
Type of antibodies to which Protein G bonds - answer✔IgG
Confirmed by diagnostic tests and throat culture - answer✔Strep Throat
Treat with penicillin and erythromycin (2) - answer✔Strep Throat, Pneumococcal pneumonia
Long term carriers have strains that are deficient in a protein (agent and protein) -
answer✔Streptococcus pyogenes, M protein
Infection that leads to multiple sequelae due to immune response - answer✔Strep Throat
Can occur after healing from strep throat - answer✔Post-Streptococcal Sequelae
Post-Streptococcal Sequelae (3) - answer✔Acute Rheumatic Fever, Chronic Rheumatic Heart
Disease (Subacute Endocarditis), Acute Post-Streptococcal Glomerulonephritis
Joint pains, chest pains, rash, and nodules under the skin - answer✔Acute Rheumatic Fever
Causes chorea - answer✔Acute Rheumatic Fever
Causes heart failure and damage to valves in 1/3 of patients - answer✔Acute Rheumatic Fever
Only develops in people who are genetically predisposed due to MHC II alleles -
answer✔Acute Rheumatic Fever
Autoimmune response involving both humoral and cell mediated response with antibodies
against the pathogen reacting with host tissue such as cardiac myosin - answer✔Acute
Rheumatic Fever
Synonym of chorea - answer✔Uncontrollable body movement
Synonym of uncontrollable body movement - answer✔Chorea
, ©THEBRIGHTSTARS 2024
Follows Acute Rheumatic Fever - answer✔Chronic Rheumatic Heart Disease
Precedes Chronic Rheumatic Heart Disease - answer✔Acute Rheumatic Fever
Can follow Strep Throat but more commonly follows streptococcal skin infection -
answer✔Acute Post-Streptococcal Glomerulonephritis
Fluid retention, high BP, blood and proteins in urine (looks like Coca Cola) - answer✔Acute
Post-Streptococcal Glomerulonephritis
Damage due to inflammatory response to pathogen antigens that accumulate in the kidney
glomeruli - answer✔Acute Post-Streptococcal Glomerulonephritis
Antibodies bind to antigens of pathogen and initiate complement response - answer✔Acute
Post-Streptococcal Glomerulonephritis
Disease caused by a pleomorphic bacterium - answer✔Diphtheria
Bacterium that forms pallisades - answer✔Corynebacterium diphtheriae
Forms black colonies in medium containing potassium-tellurite - answer✔Corynebacterium
diphtheriae
Grown on Loeffler medium, enhancing volutin granules that can be seen with methylene blue -
answer✔Corynebacterium diphtheriae
Dramatic swelling of the neck - answer✔Diphtheria
Whitish-gray pseudomembrane on the tonsils, throat, or nasal cavity - answer✔Diphtheria
Heart, kidney failure, and paralysis (nerve damage) may occur due to toxin in blood -
answer✔Diphtheria
Toxin in lysogenized strains - answer✔Corynebacterium diphtheriae
Structure made of dead cells, clotted blood, fibrin, and leukocytes - answer✔Diphtheria
Pseudomembrane
Structure that may come loose and obstruct passageway - answer✔Diphtheria
Pseudomembrane
Obstruction by a membrane that leads to suffocation - answer✔Diphtheria
Inactivates EF-2 preventing movement of mRNA on ribosomes, and causing cell death -
answer✔Diphtheria Exotoxin
Type of Diphtheria Exotoxin - answer✔A-B Exotoxin
Nester Microbiology - Respiratory System
Infections Exam Questions With Correct
Answers
Red throat with patches of pus and scattered tiny hemorrhages (not adenovirus) - answer✔Strep
Throat
Neck lymph nodes enlarged and tender (not adenovirus) - answer✔Strep Throat
Scarlet fever and roughening of the skin - answer✔Strep Throat
Many virulence factors that can alter structural components of the host or be enzymes and toxins
- answer✔Streptococcus pyogenes
80 subtypes of streptococcal protein that are adhesins and prevent phagocytosis due to C3b -
answer✔M protein
Streptococcal protein that helps in attachment to cells of the throat by adhering to fibrin -
answer✔Protein F
Produces DNase, hyaluronidase, and proteases to spread (does not cause conjunctivitis) -
answer✔Streptococcus pyogenes
Produces streptokinase to break clots - answer✔Streptococcus pyogenes
Produces protein G as an Fc receptor - answer✔Streptococcus pyogenes
Produces C5a peptidase, preventing migration of phagocytes - answer✔Streptococcus pyogenes
Produces Streploysins O and S that destroy erythrocytes and leukocytes -
answer✔Streptococcus pyogenes
Produces SPEs, aka erythrogenic toxin, in lysogenized form, superantigens that cause massive
release of cytokines causing scarlet fever and roughening of the skin - answer✔Streptococcus
pyogenes
Respiratory pathogen that may also cause "flesh eating necrotizing fasciitis" -
answer✔Streptococcus pyogenes
, ©THEBRIGHTSTARS 2024
Protein that prevents migration of phagocytes - answer✔C5a peptidase
Streptococcal protein that acts as an Fc receptor - answer✔Protein G
Protein produced to break clots - answer✔Streptokinase
Proteins that destroy erythrocytes and leukocytes - answer✔Streploysins O and S
Superantigens that cause massive release of cytokines causing scarlet fever and roughening of
the skin - answer✔SPE
GAS - answer✔Group A Streptococcus
Criterion for Lancefield grouping - answer✔Cell wall carbohydrates
Produces a hyaluronic acid capsule - answer✔Streptococcus pyogenes
Type of antibodies to which Protein G bonds - answer✔IgG
Confirmed by diagnostic tests and throat culture - answer✔Strep Throat
Treat with penicillin and erythromycin (2) - answer✔Strep Throat, Pneumococcal pneumonia
Long term carriers have strains that are deficient in a protein (agent and protein) -
answer✔Streptococcus pyogenes, M protein
Infection that leads to multiple sequelae due to immune response - answer✔Strep Throat
Can occur after healing from strep throat - answer✔Post-Streptococcal Sequelae
Post-Streptococcal Sequelae (3) - answer✔Acute Rheumatic Fever, Chronic Rheumatic Heart
Disease (Subacute Endocarditis), Acute Post-Streptococcal Glomerulonephritis
Joint pains, chest pains, rash, and nodules under the skin - answer✔Acute Rheumatic Fever
Causes chorea - answer✔Acute Rheumatic Fever
Causes heart failure and damage to valves in 1/3 of patients - answer✔Acute Rheumatic Fever
Only develops in people who are genetically predisposed due to MHC II alleles -
answer✔Acute Rheumatic Fever
Autoimmune response involving both humoral and cell mediated response with antibodies
against the pathogen reacting with host tissue such as cardiac myosin - answer✔Acute
Rheumatic Fever
Synonym of chorea - answer✔Uncontrollable body movement
Synonym of uncontrollable body movement - answer✔Chorea
, ©THEBRIGHTSTARS 2024
Follows Acute Rheumatic Fever - answer✔Chronic Rheumatic Heart Disease
Precedes Chronic Rheumatic Heart Disease - answer✔Acute Rheumatic Fever
Can follow Strep Throat but more commonly follows streptococcal skin infection -
answer✔Acute Post-Streptococcal Glomerulonephritis
Fluid retention, high BP, blood and proteins in urine (looks like Coca Cola) - answer✔Acute
Post-Streptococcal Glomerulonephritis
Damage due to inflammatory response to pathogen antigens that accumulate in the kidney
glomeruli - answer✔Acute Post-Streptococcal Glomerulonephritis
Antibodies bind to antigens of pathogen and initiate complement response - answer✔Acute
Post-Streptococcal Glomerulonephritis
Disease caused by a pleomorphic bacterium - answer✔Diphtheria
Bacterium that forms pallisades - answer✔Corynebacterium diphtheriae
Forms black colonies in medium containing potassium-tellurite - answer✔Corynebacterium
diphtheriae
Grown on Loeffler medium, enhancing volutin granules that can be seen with methylene blue -
answer✔Corynebacterium diphtheriae
Dramatic swelling of the neck - answer✔Diphtheria
Whitish-gray pseudomembrane on the tonsils, throat, or nasal cavity - answer✔Diphtheria
Heart, kidney failure, and paralysis (nerve damage) may occur due to toxin in blood -
answer✔Diphtheria
Toxin in lysogenized strains - answer✔Corynebacterium diphtheriae
Structure made of dead cells, clotted blood, fibrin, and leukocytes - answer✔Diphtheria
Pseudomembrane
Structure that may come loose and obstruct passageway - answer✔Diphtheria
Pseudomembrane
Obstruction by a membrane that leads to suffocation - answer✔Diphtheria
Inactivates EF-2 preventing movement of mRNA on ribosomes, and causing cell death -
answer✔Diphtheria Exotoxin
Type of Diphtheria Exotoxin - answer✔A-B Exotoxin
