MCAT EXAM 1 B/B Section
Questions and Answers 100%
Correct
#1 Based on the data presented in the passage, which statement best describes
the HSP110ΔE9 allele? - ANSWER - Cancer-suppressing and dominant to
HSP110WTbec
from the second chart you can see that E9 has a greater percentage....also from
figure 1 (not shown here) you can see that it is a suppressor
#2 Based on the passage, in MSI CRC primary tumor cells, the size of the deletion in
the HSP110 T17 microsatellite is inversely correlated with: - ANSWER - the number
of mature HSP110WT transcripts synthesized.
bc based on figure 1 it shows that as the size of the deletion increases, the amount
of wild type decreases and e delta 9 increases
#3 A man with a CRC mutation that results in the synthesis of HSP110ΔE9 and a
woman that does not carry this mutation in any of her tissues have a child. What is
the percent chance that the child will inherit the CRC mutation? - ANSWER - 0%
This is because it says it is in cancerous tissue, thus it is a somatic not germline
mutation (meaning it is only passed on by tissues and not through gametes)
#4 Which nucleotide pairing(s) would be recognized by the MMR system during DNA
replication?
I. dTMP and dCMP
II. dGMP and dAMP
III. dAMP and dTMP - ANSWER - I and II because T/C and G/A do not pair up but A/T
do pair up
, #5 The information in the passage best supports the conclusion that Intron 8 of
HSP110 most likely contains which of the following? - ANSWER - Splice acceptor site
Introns get spliced out of product
#6 According to the information in the passage, HSP110 is most likely which type of
protein? - ANSWER - Chaperone
because it says in the passage...facilitates proper protein folding and inhibits the
formation of nonfunctional protein aggregates
btw adhesion proteins allow cells to bind together
clathrin protein form coated vesicles
#7 Which amino acid, in addition to tryptophan, is most likely to be transported by
AT1? - ANSWER - Phenylalanine
it's cyclic and neutral like tryptophan so it would probably be recognized by the
same transport stuffq
If a man with a mutant copy of Ace2 has a child with a woman that is heterozygous
for the mutant Ace2 allele, what is the probability that the child will be a female and
homozygous for the mutant Ace2 allele? - ANSWER - 0.25
The trait is X linked so do a punnetts square
During the initiation of muscle contraction, mysosin binds actin after troponin binds
to which ion? - ANSWER - Ca2+
What is the total number of fused rings present in a steroid? - ANSWER - 4
Questions and Answers 100%
Correct
#1 Based on the data presented in the passage, which statement best describes
the HSP110ΔE9 allele? - ANSWER - Cancer-suppressing and dominant to
HSP110WTbec
from the second chart you can see that E9 has a greater percentage....also from
figure 1 (not shown here) you can see that it is a suppressor
#2 Based on the passage, in MSI CRC primary tumor cells, the size of the deletion in
the HSP110 T17 microsatellite is inversely correlated with: - ANSWER - the number
of mature HSP110WT transcripts synthesized.
bc based on figure 1 it shows that as the size of the deletion increases, the amount
of wild type decreases and e delta 9 increases
#3 A man with a CRC mutation that results in the synthesis of HSP110ΔE9 and a
woman that does not carry this mutation in any of her tissues have a child. What is
the percent chance that the child will inherit the CRC mutation? - ANSWER - 0%
This is because it says it is in cancerous tissue, thus it is a somatic not germline
mutation (meaning it is only passed on by tissues and not through gametes)
#4 Which nucleotide pairing(s) would be recognized by the MMR system during DNA
replication?
I. dTMP and dCMP
II. dGMP and dAMP
III. dAMP and dTMP - ANSWER - I and II because T/C and G/A do not pair up but A/T
do pair up
, #5 The information in the passage best supports the conclusion that Intron 8 of
HSP110 most likely contains which of the following? - ANSWER - Splice acceptor site
Introns get spliced out of product
#6 According to the information in the passage, HSP110 is most likely which type of
protein? - ANSWER - Chaperone
because it says in the passage...facilitates proper protein folding and inhibits the
formation of nonfunctional protein aggregates
btw adhesion proteins allow cells to bind together
clathrin protein form coated vesicles
#7 Which amino acid, in addition to tryptophan, is most likely to be transported by
AT1? - ANSWER - Phenylalanine
it's cyclic and neutral like tryptophan so it would probably be recognized by the
same transport stuffq
If a man with a mutant copy of Ace2 has a child with a woman that is heterozygous
for the mutant Ace2 allele, what is the probability that the child will be a female and
homozygous for the mutant Ace2 allele? - ANSWER - 0.25
The trait is X linked so do a punnetts square
During the initiation of muscle contraction, mysosin binds actin after troponin binds
to which ion? - ANSWER - Ca2+
What is the total number of fused rings present in a steroid? - ANSWER - 4
