EEB 184 Exam 1 Study Guide
thalidomide - Answer -used over counter daily
-linked to birth defects
-banned
-now helps ppl with serious illnesses (heavily regulated)
evolutionary developmental biology (evo-devo) - Answer examines interplay between
evolution, development, & ecology
developmental biology - Answer study of how animals/plants grow & develop through
adulthood
human development timeline - Answer embryonic (everything forming) & fetal (growth)
steps of developmental processes - Answer 1) fusion of sperm/egg (fertilization)
2) cell division
3) generation of diverse cell types
4) tissue organization
5) post-embryonic development (fetal = growth)
steps of developmental processes: #2-cell division - Answer -mitosis
-pluripotent (capable of giving rise to several diff. cell types)
pluripotent - Answer cell ability to give rise to several diff. cell types
steps of developmental processes: #3-generation of diverse cell types - Answer -cell
goes from undifferentiated to differentiated in two steps: specification (capable of
differentiating autonomously in neutral environment yet STILL capable of being
reversed) -> determination (capable of differentiating autonomously in neutral
environment & assumption: irreversible)
specification - Answer capable of differentiating autonomously in neutral environment
yet still capable of being reversed
determination - Answer capable of differentiating autonomously in neutral environment
& assumption: irreversible
2 types of cells - Answer autonomous (differentiates w/out external signals) &
conditional (dependent on interactions w/neighboring cells)
, autonomous cell - Answer differentiates w/out external signals
conditional cell - Answer dependent on interactions w/neighboring cells
determination example - Answer lizard leg cut off = regeneration
steps of developmental processes: #4-tissue organization (patterning) - Answer process
that makes higher order 3D structures in embryo
steps of developmental processes: #5-post-embryonic development - Answer embryo ->
fetus -> adulthood
ex) metamorphosis/regeneration/growth to full size
Quail/Duck beak example: At which stage in the progression from "undifferentiated to
differentiated cell" were the pre-transplant neural crest cells? - Answer determined
housekeeping genes - Answer -genes that encode proteins w/roles in essential
processes in all cells of the body
-to keep basic functions of cell
ex) metabolism
toolkit genes - Answer -genes that encode proteins w/roles in the formation & patterning
of body plan & body parts
ex) hox genes
2 types of toolkit genes - Answer signaling pathway genes & transcription factors
signaling pathway genes - Answer -mechanism of communication of one cell to another
-coordinate multiple cell actions responding to their microenvironment
transcription factors - Answer regulate the expression/transcription of other genes
during development
housekeeping, transcription factor, or signaling protein?
-glycolysis: Gapdh is a gene involved in glycolysis that is expressed in all cells.
Gapdh = ? - Answer Gapdh = housekeeping gene
housekeeping, transcription factor, or signaling protein?
when lizard's hand cut off, Shh is a gene involved in patterning of several body parts,
including the digits.
Shh = ? - Answer Shh = signaling factor
Drosophia toolkit at AP axis:
thalidomide - Answer -used over counter daily
-linked to birth defects
-banned
-now helps ppl with serious illnesses (heavily regulated)
evolutionary developmental biology (evo-devo) - Answer examines interplay between
evolution, development, & ecology
developmental biology - Answer study of how animals/plants grow & develop through
adulthood
human development timeline - Answer embryonic (everything forming) & fetal (growth)
steps of developmental processes - Answer 1) fusion of sperm/egg (fertilization)
2) cell division
3) generation of diverse cell types
4) tissue organization
5) post-embryonic development (fetal = growth)
steps of developmental processes: #2-cell division - Answer -mitosis
-pluripotent (capable of giving rise to several diff. cell types)
pluripotent - Answer cell ability to give rise to several diff. cell types
steps of developmental processes: #3-generation of diverse cell types - Answer -cell
goes from undifferentiated to differentiated in two steps: specification (capable of
differentiating autonomously in neutral environment yet STILL capable of being
reversed) -> determination (capable of differentiating autonomously in neutral
environment & assumption: irreversible)
specification - Answer capable of differentiating autonomously in neutral environment
yet still capable of being reversed
determination - Answer capable of differentiating autonomously in neutral environment
& assumption: irreversible
2 types of cells - Answer autonomous (differentiates w/out external signals) &
conditional (dependent on interactions w/neighboring cells)
, autonomous cell - Answer differentiates w/out external signals
conditional cell - Answer dependent on interactions w/neighboring cells
determination example - Answer lizard leg cut off = regeneration
steps of developmental processes: #4-tissue organization (patterning) - Answer process
that makes higher order 3D structures in embryo
steps of developmental processes: #5-post-embryonic development - Answer embryo ->
fetus -> adulthood
ex) metamorphosis/regeneration/growth to full size
Quail/Duck beak example: At which stage in the progression from "undifferentiated to
differentiated cell" were the pre-transplant neural crest cells? - Answer determined
housekeeping genes - Answer -genes that encode proteins w/roles in essential
processes in all cells of the body
-to keep basic functions of cell
ex) metabolism
toolkit genes - Answer -genes that encode proteins w/roles in the formation & patterning
of body plan & body parts
ex) hox genes
2 types of toolkit genes - Answer signaling pathway genes & transcription factors
signaling pathway genes - Answer -mechanism of communication of one cell to another
-coordinate multiple cell actions responding to their microenvironment
transcription factors - Answer regulate the expression/transcription of other genes
during development
housekeeping, transcription factor, or signaling protein?
-glycolysis: Gapdh is a gene involved in glycolysis that is expressed in all cells.
Gapdh = ? - Answer Gapdh = housekeeping gene
housekeeping, transcription factor, or signaling protein?
when lizard's hand cut off, Shh is a gene involved in patterning of several body parts,
including the digits.
Shh = ? - Answer Shh = signaling factor
Drosophia toolkit at AP axis:
