TestlBanklAdvancedlPhysiologylandlPathophysiologylEssentialslforl ClinicallPracticel1stlEditionlTkacs 1
Advanced Physiology and Pathophysiology Essentials forC
l l l l l l
linical Practice 1st Edition Tkacs
l l l l
Chapterl1.lTHEl FOUNDATIONALlCONCEPTSlOFlCLINICALPRACTICE
1. Thelcharacteristic,l localizedlcardinallsignsloflacutelinflammationlinclude:
A) fever.
B) fatigue.
C) redness.
D) granuloma.
2.
Thelvascular,lhemodynamiclstageloflacutelinflammationlislinitiatedlbylmom
entarylvasoconstrictionlfollowedl bylvasodilationlthatlcausesllocalized:
A) bleeding.
B) congestion.
C) palelskin.
D) coolness.
3.
Thelcellularlstageloflacutelinflammationlislmarkedlbylthelmovementloflleu
kocyteslintolthelarea.lWhichl oflthelfollowinglcellslarriveslearlylinlgreatlnumb
ers?
A) Basophils
B) Lymphocytes
C) Neutrophils
D) Platelets
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TestlBanklAdvancedlPhysiologylandlPathophysiologylEssentialslforlClinicallPracticel1stlEditionlTkacs 2
4.
Thelphagocytosisl processlinvolvesl threeldistinctlsteps.lWhatl islthelinitiall
steplinlthelprocess?
A) Engulfment
B) Intracellularlkilling
C) Antigenlmargination
D) Recognitionlandladherence
5.
Whichloflthel followinglmediatorsloflinflammationlcausesl increasedlcapillaryl
permeabilitylandlpain?
A) Serotonin
B) Histamine
C) Bradykinin
D) Nitricloxide
6.
Inflammatorylexudateslarelalcombinationloflseverall types.l Whichloflthelf
ollowinglexudateslislcomposedloflenmeshedlnecroticlcells?
A) Serous
B) Fibrinous
C) Suppurative
D) Membranous
7. Thelacute-
phaselsystemiclresponselusuallylbeginsl withinlhoursl oflthel onsetloflinflammati
onlandlincludes:
A) feverlandllethargy.
B) decreasedlC-reactivelprotein.
C) positivelnitrogenlbalance.
D) lowlerythrocytelsedimentationlrate.
8.
Inlcontrastltolacutelinflammation,lchronicl inflammationlislcharacterizedlbyl
whichloflthelfollowinglphenomena?
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TestlBanklAdvancedlPhysiologylandlPathophysiologylEssentialslforlClinicallPracticel1stlEditionlTkacs 3
A) Profuselfibrinouslexudation
B) Alshiftltolthelleftl oflgranulocytes
C) Metaboliclandlrespiratorylalkalosis
D) Lymphocytosislandlactivatedl macrophages
9. Exogenouslpyrogensl(interleukin-
1)l andlthelpresenceloflbacterial inlthelbloodlleadltolthelreleaseloflendogenouslpyr
ogenslthat:
A) stabilizelthermallcontrollinlthelbrain.
B) producelleukocytosisl andlanorexia.
C) blocklvirallreplicationlinlcells.
D) inhibitlprostaglandinlrelease.
10 Anlolderladultlpatientlhasljustlshearedlthelskinlonlherlelbowlwhilelattempted
.
tolboostlherselfluplinlbed,lanleventlthatlhaslprecipitatedlacutelinflammationli
nlthelregionlsurroundinglthelwound.lWhichloflthel followingleventslwillloccurl
duringlthelvascularlstageloflthelpatientslinflammation?
A) Outpouringloflexudatelintolinterstitiallspaces
B) Chemotaxis
C) Accumulationloflleukocyteslalonglthelepithelium
D) Phagocytosisloflcellularldebris
11 Whichloflthelfollowingl individualslmostl likelylhaslthel highestlrisklof
. experiencinglchroniclinflammation?
A) Alpatientlwholhaslrecentlylbeenldiagnosedl withltypel2ldiabetes
B) Alpatientlwholislalcarrierloflanlantibiotic-resistantlorganism
C) Alpatientlwholisltakinglorallantibioticsl forl anlupperlrespiratorylinfection
D) Alpatientlwholislmorbidlylobeselandlwholhaslalsedentaryllifestyle
12 Whichloflthelfollowing core body temperatures is within normal range?
.
A) 35.9Cl(96.6F)
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B) 38.0Cl(100.4F)
C) 35.5Cl(95.9F)
D) 37.3Cl(99.1F)
13 Alpostsurgicallpatientl wholislrecoveringl inlthelpostanestheticlrecoverylunit
.
stateslthatlshelisl freezinglcold.lWhichloflthelfollowinglmeasureslisllikelyltolb
elinitiatedlinlthelpatientslhypothalamuslinlanleffortl tolreducelheatlloss?
A) Openingloflarteriovenousl(AV)lshunts
B) Reducedlexhalationloflwarmedlair
C) Contractionloflpilomotorl muscles
D) Decreasedlurinelproduction
14 Anlelderlylpatientl isldressedl onlylinlalhospitallgownlandlcomplainsl ofla
.
draftlinlherlroom.lConsequently,lshelhaslrequestedlal warmlblanketlwhilelshels
itslinlherlwheelchair.lWhichloflthelfollowinglmechanismsloflheatllosslislmostllik
elylthelprimarylcauseloflherlrequest?
A) Evaporationlandl conduction
B) Radiationlandl convection
C) Conductionlandl convection
D) Convectionlandl evaporation
15 Whichloflthel followinglpathophysiologicl processesl arelcapableloflinducing
. thelproductionloflpyrogens?lSelectlalllthatlapply.
A) Acutelinflammation
B) Obesity
C) Myocardiallinfarction
D) Malignancy
E) Renallfailure
16 Whichloflthel followinglpatientslislmostllikelyltolbel susceptiblelto
. developinglal neurogeniclfever?