NURS 5315 UTA Exam 2 with Verified Solutions
Prostaglandins Correct-Released when mast cells degranulate, are produced by the
arachidonic pathway. Cause vasodilation, platelet aggregation at site of injury, pain, and fever.
Chemotactic factors Correct-Biochemical substance that attracts leukocyte to the site of
inflammation
Neutrophils Correct-Predominant leukocyte at work during the early stages of acute
inflammation
Monocytes Correct-Become macrophages when entering the tissue, responsible for
presenting antigens to the CD4 cell which triggers T-cell immunity and B-cell immunity.
Releases additional cytokines IL1, IL6, TNF.
Cytokine IL1 function Correct-Causes fever, activates phagocytes & lymphocytes and also
increases the release of IL6a
,HIV EIA (3rd generation immunoassay) Correct-can use urine, saliva, or serum (most
accurate), need to wait until 12 weeks post exposure to see antibodies, >99% accurate
4th generation immunoassay- "gold standard"
measures P24 antigen
can test 10 days post exposure
Mast cell Correct-Cellular bags of granules located in loose connective tisssue close to
blood vessels. Activation initiates inflammatory process.
Histamine Correct-Causes vasodilation, increases vascular permeability, increases blood
flow to the site of injury- causes erythema and swelling.
Cytokines Correct-Soluble factors that contribute to the regulation of innate or adaptive
resistance by affecting other neighboring cells. Can be pro-inflammatory or anti-inflammatory.
Can react quickly or be more delayed.
, Leukotrines Correct-Released when mast cells degranulate, prolong the inflammatory
process. Cause vasodilation, attract neutrophils, monocytes, and eosinophils.target of
inhibition for singular.
Cytokine IL6 function Correct-Stimulates production of acute phase reactants and
promotes growth and stimulation of RBCs
Cytokine TNF function Correct-Causes fever, increases synthesis of proinflammatory
proteins by liver, causes muscle wasting, induces thrombosis
Cytokine growth factor function Correct-Promotes production and maturation of
neutrophils
Complement Correct-Functions include bacterial lysis, vasodilation and increased vascular
permeability, triggers mast cell degranulation, chemotaxis, and opsonization.
Kinin Correct-Converted to bradykinin which is responsible for pain and chemotaxis, and it
increases vascular permeability and vasodilation.
Prostaglandins Correct-Released when mast cells degranulate, are produced by the
arachidonic pathway. Cause vasodilation, platelet aggregation at site of injury, pain, and fever.
Chemotactic factors Correct-Biochemical substance that attracts leukocyte to the site of
inflammation
Neutrophils Correct-Predominant leukocyte at work during the early stages of acute
inflammation
Monocytes Correct-Become macrophages when entering the tissue, responsible for
presenting antigens to the CD4 cell which triggers T-cell immunity and B-cell immunity.
Releases additional cytokines IL1, IL6, TNF.
Cytokine IL1 function Correct-Causes fever, activates phagocytes & lymphocytes and also
increases the release of IL6a
,HIV EIA (3rd generation immunoassay) Correct-can use urine, saliva, or serum (most
accurate), need to wait until 12 weeks post exposure to see antibodies, >99% accurate
4th generation immunoassay- "gold standard"
measures P24 antigen
can test 10 days post exposure
Mast cell Correct-Cellular bags of granules located in loose connective tisssue close to
blood vessels. Activation initiates inflammatory process.
Histamine Correct-Causes vasodilation, increases vascular permeability, increases blood
flow to the site of injury- causes erythema and swelling.
Cytokines Correct-Soluble factors that contribute to the regulation of innate or adaptive
resistance by affecting other neighboring cells. Can be pro-inflammatory or anti-inflammatory.
Can react quickly or be more delayed.
, Leukotrines Correct-Released when mast cells degranulate, prolong the inflammatory
process. Cause vasodilation, attract neutrophils, monocytes, and eosinophils.target of
inhibition for singular.
Cytokine IL6 function Correct-Stimulates production of acute phase reactants and
promotes growth and stimulation of RBCs
Cytokine TNF function Correct-Causes fever, increases synthesis of proinflammatory
proteins by liver, causes muscle wasting, induces thrombosis
Cytokine growth factor function Correct-Promotes production and maturation of
neutrophils
Complement Correct-Functions include bacterial lysis, vasodilation and increased vascular
permeability, triggers mast cell degranulation, chemotaxis, and opsonization.
Kinin Correct-Converted to bradykinin which is responsible for pain and chemotaxis, and it
increases vascular permeability and vasodilation.
