MMSC436 Final Exam (with Complete Solutions)

The three levels of dysfunction that may be evaluated in a patient with an endocrine problem are primary, secondary, and tertiary. The possible defective sites that correspond to these primary, secondary, and tertiary levels of dysfunction are, respective correct answers Target gland, pituitary hypothalamus Pituitary secretion of adrenocorticotropic hormone (ACTH) is inhibited by elevated levels of: a. Aldosterone b. Cortisol c. Estradiol-17b d. Progesterone e. Epinephrine correct answers b An example of ectopic hormone production would be: a. Prolactin production by pituitary tumors b. Corticotropin releasing hormone from hypothalamus c. Growth hormone production by lung tumors d. Growth hormone production by pituitary tumors correct answers c The definitive diagnosis of primary adrenal insufficiency requires demonstration of: a. Decreased urinary 17-keto and 17-hydroxysteroids b. Decreased cortisol production c. Impaired response to ACTH stimulation d. Increased urinary cortisol excretion after metyrapone (inhibitor) treatment correct answers c As a screening test for Cushing's syndrome, the physician wishes to see whether a patient exhibits normal diurnal rhythm of his cortisol secretion. At what time should the specimens be drawn for plasma cortisol determination? (daytime work schedule) a. 6 am, noon b. 8 am, 2 pm c. 8am, 6pm d. Noon, 6pm correct answers c The parent substance of all steroid hormones a. Cortisol b. Catecholamines c. Progesterone d. Cholesterol e. Amino acids correct answers d Which is normally the most abundant corticosteroid hormone secreted by the adrenal cortex? a. Cortisol b. Dehydroepiandrosterone c. Aldosterone d. Corticosterone correct answers a