NURS 3304 Analgesics Test With
Solution
What is tolerance - ANSWER a state in which a larger dose is required to
produce the same response that could formerly be elicited by a smaller dose
dependence - ANSWER withdrawal syndrome will occur if the drug is
stopped or dose is rapidly reduced
addiction - ANSWER disease manifested by compulsive substance use despite
harmful consequences
nociceptive pain - ANSWER direct stimulation of pain receptors
types of nociceptive pain - ANSWER somatic: arising from skin, bone, joint,
muscle, or connective tissue; dull, aching, throbbing pain
visceral: arising from intestinal organs; deep aching squeezing pain
acetylsalicylic acid - ANSWER aspirin
aspirin MOA - ANSWER inhibits cyclooxygenase and PG's and prevents
platelet formation
ADR of aspirin - ANSWER GI (dyspepsia and irritation, ulceration)
Anticoagulant effects
impaired kidney function
salicylism (tinnitus, headache, dizziness)
Reyes Syndrome (avoid in children with viral illness)
, ibuprofen - ANSWER NSAID
naproxen - ANSWER NSAID
indomethacin - ANSWER NSAID
dicofenac - ANSWER NSAID
ketorolac - ANSWER NSAID
elodolac - ANSWER NSAID
ketoprofen - ANSWER NSAID
MOA of NSAID - ANSWER inhibit PG synthesis via inhibition of COX 1 and
COX 2 for mild to moderate pain
NSAID cautions - ANSWER renal disease: vasoconstriction
GI: inhibition of protective effects
Solution
What is tolerance - ANSWER a state in which a larger dose is required to
produce the same response that could formerly be elicited by a smaller dose
dependence - ANSWER withdrawal syndrome will occur if the drug is
stopped or dose is rapidly reduced
addiction - ANSWER disease manifested by compulsive substance use despite
harmful consequences
nociceptive pain - ANSWER direct stimulation of pain receptors
types of nociceptive pain - ANSWER somatic: arising from skin, bone, joint,
muscle, or connective tissue; dull, aching, throbbing pain
visceral: arising from intestinal organs; deep aching squeezing pain
acetylsalicylic acid - ANSWER aspirin
aspirin MOA - ANSWER inhibits cyclooxygenase and PG's and prevents
platelet formation
ADR of aspirin - ANSWER GI (dyspepsia and irritation, ulceration)
Anticoagulant effects
impaired kidney function
salicylism (tinnitus, headache, dizziness)
Reyes Syndrome (avoid in children with viral illness)
, ibuprofen - ANSWER NSAID
naproxen - ANSWER NSAID
indomethacin - ANSWER NSAID
dicofenac - ANSWER NSAID
ketorolac - ANSWER NSAID
elodolac - ANSWER NSAID
ketoprofen - ANSWER NSAID
MOA of NSAID - ANSWER inhibit PG synthesis via inhibition of COX 1 and
COX 2 for mild to moderate pain
NSAID cautions - ANSWER renal disease: vasoconstriction
GI: inhibition of protective effects
