z z z z z z
, Applied “Pathophysiology “A “Conceptual “Approach “to “the“Mech
z z z z z z z
anisms “of “Disease “4th “Edition “Braun “Test “Bank
z z z z z z z
Chapterz“1Introductionz“toz“Pathophysiology
1. Thez“nucleus
,z“whichz“isz“essentialz“forz“functionz“andz“survivalz“ofz“thez“cell.
A) isz“thez“sitez“ofz“proteinz“synthesis
B) containsz“thez“geneticz“code
C) transformsz“cellularz“energy
D) initiatesz“aerobicz“metabolism
2. Althoughz“energyz“isz“notz“madez“inz“mitochondria,z“theyz“arez“knownz“asz“thez“
powerz“plantsz“ofz“thez“cellz“becausez“they:
A) containz“RNAz“forz“proteinz“synthesis.
B) utilizez“glycolysisz“forz“oxidativez“energy.
C) extractz“energyz“fromz“organicz“compounds.
D) storez“calciumz“bondsz“forz“musclez“contractions.
3. Althoughz“thez“basicz“structurez“ofz“thez“cellz“plasmaz“membranez“isz“formedz“byz“
az“lipidz“bilayer,z“mostz“ofz“thez“specificz“membranez“functionsz“arez“carriedz“outz“
by:
A) boundz“andz“transmembranez“proteins.
B) complex,z“longz“carbohydratez“chains.
C) surfacez“antigensz“andz“hormonez“receptors.
D) az“gatingz“systemz“ofz“selectivez“ionz“channels.
4. Toz“effectivelyz“relayz“signals,z“cell-to-
cellz“communicationz“utilizesz“chemicalz“messengerz“systemsz“that:
A) displacez“surfacez“receptorz“proteins.
B) accumulatez“withinz“cellz“gapz“junctions.
C) bindz“toz“contractilez“microfilaments.
D) releasez“secretionsz“intoz“extracellularz“fluid.
5. Aerobicz“metabolism,z“alsoz“knownz“asz“oxidativez“metabolism,z“providesz“energyz“by
:
,A) removingz“thez“phosphatez“bondsz“fromz“ATP.
B) combiningz“hydrogenz“andz“oxygenz“toz“formz“water.
C) activatingz“pyruvatez“storedz“inz“thez“cytoplasm.
D) breakingz“downz“glucosez“toz“formz“lacticz“acid.
6. Exocytosis,z“thez“reversez“ofz“endocytosis,z“isz“importantz“in
intoz“thez“extracellularz“fluid.
A) Engulfingz“andz“ingestingz“fluidz“andz“proteinsz“forz“transport
B) Killing,z“degrading,z“andz“dissolvingz“harmfulz“microorganisms
C) Removingz“cellularz“debrisz“andz“releasingz“synthesizedz“substances
D) Destructionz“ofz“particlesz“byz“lysosomalz“enzymesz“forz“secretion
7. Thez“processz“responsiblez“forz“generatingz“andz“conductingz“membranez“potentialsz“is
:
A) diffusionz“ofz“current-carryingz“ions.
B) millivoltagez“ofz“electricalz“potential.
C) polarizationz“ofz“chargedz“particles.
D) ionz“channelz“neurotransmission.
8. Epithelialz“tissuesz“arez“classifiedz“accordingz“toz“thez“shapez“ofz“thez“cellsz“and
z“thez“numberz“ofz“layers.z“Whichz“ofz“thez“followingz“isz“az“correctlyz“matchedz“
descriptionz“andz“typez“ofz“epithelialz“tissue?
A) Simplez“epithelium:z“cellsz“inz“contactz“withz“intercellularz“matrix;z“somez“d
oz“notz“extendz“toz“surface
B) Stratifiedz“epithelium:z“singlez“layerz“ofz“cells;z“allz“cellsz“restz“onz“base
mentz“membrane
C) Glandularz“epithelium:z“arisez“fromz“surfacez“epitheliaz“andz“underly
ingz“connectivez“tissue
D) Pseudostratifiedz“epithelium:z“multiplez“layersz“ofz“cells;z“deepestz“layerz“rest
sz“onz“basementz“membrane
9. Connectivez“tissuez“containsz“fibroblastsz“thatz“arez“responsiblez“for:
A) providingz“az“fibrousz“frameworkz“forz“capillaries.
B) synthesisz“ofz“collagen,z“elastin,z“andz“reticularz“fibers.
, C) formingz“tendonsz“andz“thez“fasciaz“thatz“coversz“muscles.
D) fillingz“spacesz“betweenz“tissuesz“toz“keepz“organsz“inz“place.
10. Althoughz“allz“musclez“tissuez“cellsz“havez“somez“similarities,z“smoothz“musclez“
(alsoz“knownz“asz“involuntaryz“muscle)z“differsz“by:
A) havingz“densez“bodiesz“attachedz“toz“actinz“filaments.
B) containingz“sarcomeresz“betweenz“Zz“linesz“andz“Mz“bands.
C) havingz“rapidz“contractionsz“andz“abundantz“cross-striations.
D) contractingz“inz“responsez“toz“increasedz“intracellularz“calcium.
11. Whichz“ofz“thez“followingz“aspectsz“ofz“thez“functionz“ofz“thez“nucleusz“isz“perfor
medz“byz“ribosomalz“RNAz“(rRNA)?
A) Copyingz“andz“carryingz“DNAz“instructionsz“forz“proteinz“synthesis
B) Carryingz“aminoz“acidsz“toz“thez“sitez“ofz“proteinz“synthesis
C) Providingz“thez“sitez“wherez“proteinz“synthesisz“occurs
D) Regulatingz“andz“controllingz“proteinz“synthesis
12. Breakdownz“andz“removalz“ofz“foreignz“substancesz“andz“worn-
outz“cellz“partsz“arez“performedz“byz“whichz“ofz“thez“followingz“organelles?
A) Lysosomes
B) Golgiz“apparatus
C) Ribosomes
D) Endoplasmicz“reticulumz“(ER)
13. Impairmentz“inz“thez“functionz“ofz“peroxisomesz“wouldz“resultz“in:
A) inadequatez“sitesz“forz“proteinz“synthesis.
B) anz“inabilityz“toz“transportz“cellularz“productsz“acrossz“thez“cellz“membrane.
C) insufficientz“energyz“productionz“withinz“az“cell.
D) accumulationz“ofz“freez“radicalsz“inz“thez“cytoplasm.
14. Afterz“severalz“monthsz“ofz“tryingz“toz“conceive,z“az“couplez“isz“undergoingz“fertil
ityz“testing.z“Semenz“analysisz“indicatesz“thatz“thez“mansz“spermz“havez“decreasedz“
motility,z“az“findingz“thatz“isz“thoughtz“toz“underliez“thez“couplesz“inabilityz“toz“beco
mez“pregnant.