BIOD322
Neuroscience
FINAL EXAM GUIDE
© Portage 2024/2025
,1. Which neurotransmitter is primarily involved in the modulation
of pain?
a) Dopamine
b) Serotonin
c) GABA
d) Substance P
Answer: d) Substance P
Rationale: Substance P is a neuropeptide that functions as a
neurotransmitter and neuromodulator and is associated with the
transmission of pain signals into the central nervous system.
2. In the context of synaptic plasticity, what does LTP stand for?
a) Long-Term Potentiation
b) Long-Term Progression
c) Long-Term Performance
d) Long-Term Prediction
Answer: a) Long-Term Potentiation
Rationale: Long-Term Potentiation (LTP) is a long-lasting
enhancement in signal transmission between two neurons that
results from stimulating them synchronously.
© Portage 2024/2025
, 3. What is the role of astrocytes in the central nervous system?
a) Modulating neuronal activity
b) Myelinating peripheral neurons
c) Forming the blood-brain barrier
d) Conducting action potentials
Answer: c) Forming the blood-brain barrier
Rationale: Astrocytes contribute to the formation and
maintenance of the blood-brain barrier, which protects the brain
from harmful substances in the bloodstream.
4. Which ion's influx is most directly responsible for the
depolarization phase of an action potential?
a) Sodium (Na+)
b) Potassium (K+)
c) Calcium (Ca2+)
d) Chloride (Cl-)
Answer: a) Sodium (Na+)
Rationale: During the depolarization phase of an action potential,
sodium ions (Na+) rapidly enter the neuron, causing the interior to
become more positive.
© Portage 2024/2025
Neuroscience
FINAL EXAM GUIDE
© Portage 2024/2025
,1. Which neurotransmitter is primarily involved in the modulation
of pain?
a) Dopamine
b) Serotonin
c) GABA
d) Substance P
Answer: d) Substance P
Rationale: Substance P is a neuropeptide that functions as a
neurotransmitter and neuromodulator and is associated with the
transmission of pain signals into the central nervous system.
2. In the context of synaptic plasticity, what does LTP stand for?
a) Long-Term Potentiation
b) Long-Term Progression
c) Long-Term Performance
d) Long-Term Prediction
Answer: a) Long-Term Potentiation
Rationale: Long-Term Potentiation (LTP) is a long-lasting
enhancement in signal transmission between two neurons that
results from stimulating them synchronously.
© Portage 2024/2025
, 3. What is the role of astrocytes in the central nervous system?
a) Modulating neuronal activity
b) Myelinating peripheral neurons
c) Forming the blood-brain barrier
d) Conducting action potentials
Answer: c) Forming the blood-brain barrier
Rationale: Astrocytes contribute to the formation and
maintenance of the blood-brain barrier, which protects the brain
from harmful substances in the bloodstream.
4. Which ion's influx is most directly responsible for the
depolarization phase of an action potential?
a) Sodium (Na+)
b) Potassium (K+)
c) Calcium (Ca2+)
d) Chloride (Cl-)
Answer: a) Sodium (Na+)
Rationale: During the depolarization phase of an action potential,
sodium ions (Na+) rapidly enter the neuron, causing the interior to
become more positive.
© Portage 2024/2025