BCH403 Exam Questions| Already
Answered| GRADED A+
T/F Under physiological conditions, a catabolic pathway will run backwards when there is a high
concentration of ATP. - ANSWER-False
T/F ATP is the energy currency of the cell. - ANSWER-True
Which one of the following statements is correct regarding metabolic pathways? - ANSWER-Metabolic
pathways always end at a specific molecule.
_______ is a bidirectional glucose transporter. - ANSWER-GLUT2
The glycolytic enzyme that is responsible for trapping glucose in a skeletal muscle cell is _______. -
ANSWER-Hexokinase
The most important regulatory step of glycolysis is ______. - ANSWER-Phosphofructokinase-1
T/F Pyruvate kinase is the only step of glycolysis that is regulated and generates ATP. - ANSWER-True
The most important regulatory step of gluconeogenesis is __________. - ANSWER-Fructose-1,6-
bisphosphatase
The gluconeogenesis enzyme found in the endoplasmic reticulum is ______________. - ANSWER-
Glucose-6-phosphatase
T/F Adipose tissue is capable of complete gluconeogenesis (i.e. can synthesize glucose). - ANSWER-False
T/F The liver is the major site of gluconeogenesis. - ANSWER-True
,Glycogen synthase: - ANSWER-Is the required site of glycogenesis.
Glycogenolysis: - ANSWER-Involves the synthesis of new a(1->4) linkages.
T/F a-amylase and isomaltase are required for the breakdown of dietary glycogen - ANSWER-True
In glycogen metabolism, the branching enzyme: - ANSWER-Synthesizes all a(1->6) linkages.
Glucose-6-phosphate is not involved in the regulation of: - ANSWER-Glucokinase
T/F Insulin increases pyruvate kinase activity and decreases the activity of phosphoenolpyruvate
carboxykinase. - ANSWER-False
Fructose-2,6-bisphosphate: - ANSWER-Activates glycolysis via phosphofructokinase-1 while inactivating
glycogenolysis via fructose-1,6-bisphosphatase
In skeletal muscles, glycogen synthase: - ANSWER-Is always active when not phosphorylated
Pyruvate dehydrogenase is NOT regulated by: - ANSWER-Glucagon
The major regulated step in the TCA cycle is: - ANSWER-Citrate synthase
Lactate dehydrogenase: - ANSWER-Replenishes NAD+ so that the glycolytic enzyme glyceraldehyde-3-
phosphate dehydrogenase can continue to run
T/F The entire Tricarboxylic Acid Cycle (or Krebs cycle or TCA cycle) is found in the mitochondria. -
ANSWER-True
How many electrons can Cyt C carry? - ANSWER-1
, When 3 electrons are transferred onto oxygen (O2), the result is: - ANSWER-hydroxyl radical
T/F Complex I is both a flavoprotein and cytochrome - ANSWER-False
In the liver, cytosolic electrons are transported into the respiratory chain via: - ANSWER-
Malate/aspartate shuttle
The site of ATP synthesis in Complex V (or ATP synthase or F0F1 complex) is: - ANSWER-aB-subunits
T/F Phosphate translocase may transport a proton (H+) into the mitochondrial matrix. - ANSWER-True
Which one of the following is not a proton pump? - ANSWER-Complex II
T/F Lipoprotein lipase is the only lipase in humans that can cleave all three fatty acids off of the glycerol
backbone. - ANSWER-True
T/F Triacylglycerols are slightly amphipathic. - ANSWER-False
Triacylglycerols that are synthesized in the liver are packaged into: - ANSWER-Very low density
lipoproteins
Dietary cholesterol is transported to and processed in: - ANSWER-Liver
T/F Adipose triglyceride lipase is the rate limiting step of lipolysis (fat mobilization). - ANSWER-True
The regulated step of beta-oxidation is: - ANSWER-Carnitine acyltransferase I
During beta-oxidation, cis-unsaturated fatty acids generate less energy than saturated fatty acids
because: - ANSWER-There is no net gain of electrons during the FAD-dependent oxidation step when
double bonds are present.
Answered| GRADED A+
T/F Under physiological conditions, a catabolic pathway will run backwards when there is a high
concentration of ATP. - ANSWER-False
T/F ATP is the energy currency of the cell. - ANSWER-True
Which one of the following statements is correct regarding metabolic pathways? - ANSWER-Metabolic
pathways always end at a specific molecule.
_______ is a bidirectional glucose transporter. - ANSWER-GLUT2
The glycolytic enzyme that is responsible for trapping glucose in a skeletal muscle cell is _______. -
ANSWER-Hexokinase
The most important regulatory step of glycolysis is ______. - ANSWER-Phosphofructokinase-1
T/F Pyruvate kinase is the only step of glycolysis that is regulated and generates ATP. - ANSWER-True
The most important regulatory step of gluconeogenesis is __________. - ANSWER-Fructose-1,6-
bisphosphatase
The gluconeogenesis enzyme found in the endoplasmic reticulum is ______________. - ANSWER-
Glucose-6-phosphatase
T/F Adipose tissue is capable of complete gluconeogenesis (i.e. can synthesize glucose). - ANSWER-False
T/F The liver is the major site of gluconeogenesis. - ANSWER-True
,Glycogen synthase: - ANSWER-Is the required site of glycogenesis.
Glycogenolysis: - ANSWER-Involves the synthesis of new a(1->4) linkages.
T/F a-amylase and isomaltase are required for the breakdown of dietary glycogen - ANSWER-True
In glycogen metabolism, the branching enzyme: - ANSWER-Synthesizes all a(1->6) linkages.
Glucose-6-phosphate is not involved in the regulation of: - ANSWER-Glucokinase
T/F Insulin increases pyruvate kinase activity and decreases the activity of phosphoenolpyruvate
carboxykinase. - ANSWER-False
Fructose-2,6-bisphosphate: - ANSWER-Activates glycolysis via phosphofructokinase-1 while inactivating
glycogenolysis via fructose-1,6-bisphosphatase
In skeletal muscles, glycogen synthase: - ANSWER-Is always active when not phosphorylated
Pyruvate dehydrogenase is NOT regulated by: - ANSWER-Glucagon
The major regulated step in the TCA cycle is: - ANSWER-Citrate synthase
Lactate dehydrogenase: - ANSWER-Replenishes NAD+ so that the glycolytic enzyme glyceraldehyde-3-
phosphate dehydrogenase can continue to run
T/F The entire Tricarboxylic Acid Cycle (or Krebs cycle or TCA cycle) is found in the mitochondria. -
ANSWER-True
How many electrons can Cyt C carry? - ANSWER-1
, When 3 electrons are transferred onto oxygen (O2), the result is: - ANSWER-hydroxyl radical
T/F Complex I is both a flavoprotein and cytochrome - ANSWER-False
In the liver, cytosolic electrons are transported into the respiratory chain via: - ANSWER-
Malate/aspartate shuttle
The site of ATP synthesis in Complex V (or ATP synthase or F0F1 complex) is: - ANSWER-aB-subunits
T/F Phosphate translocase may transport a proton (H+) into the mitochondrial matrix. - ANSWER-True
Which one of the following is not a proton pump? - ANSWER-Complex II
T/F Lipoprotein lipase is the only lipase in humans that can cleave all three fatty acids off of the glycerol
backbone. - ANSWER-True
T/F Triacylglycerols are slightly amphipathic. - ANSWER-False
Triacylglycerols that are synthesized in the liver are packaged into: - ANSWER-Very low density
lipoproteins
Dietary cholesterol is transported to and processed in: - ANSWER-Liver
T/F Adipose triglyceride lipase is the rate limiting step of lipolysis (fat mobilization). - ANSWER-True
The regulated step of beta-oxidation is: - ANSWER-Carnitine acyltransferase I
During beta-oxidation, cis-unsaturated fatty acids generate less energy than saturated fatty acids
because: - ANSWER-There is no net gain of electrons during the FAD-dependent oxidation step when
double bonds are present.
