BCH 403 FINAL TEST QUESTIONS
WITH VERIFIED ANSWERS
The composition of a bilayer has been modified to include 10% cholesterol. Which of
the following is true regarding the new properties of the bilayer - Answer-The Tm of the
bilayer has not changed
AND
The rigidity of the cholesterol broadens the transition temperature of the bilayer
A integral membrane protein that is expected to b eon the plasma membrane is instead
found on the cytoplasm. Which of the following would explain this result - Answer-The
SRP is not able to recognize the N-terminal signal sequence
What might occur if the Zn2+ prosthetic group was no longe present in the enzyme
Carboxypeptidase A during a reaction? - Answer-the delta G double dagger would
increase
Anabolic pathways require an energy input to synthesize mroe complex molecules form
less complex molecules - Answer-True
Phosphoenolpyruvate carboxykinase is found within the mitochondria - Answer-false
Fructose-2,6-bisphosphate inactviates fructose-1,6-bisphophatase by directly binding to
the active site of the enzyme (i.e. its a competitive inhibitor) - Answer-false
Malate/Aspartate shuttle is used by the liver to transport two electrons from cytosolic
NADH onto mitochondrial NADH - Answer-True
Succinate dehydrogenase complex draws two electrons from succinate and donates
them to coenzyme Q - Answer-True
Hexokinase phosphorylates glucose so that glucose can not be transported out of the
cell - Answer-true
During glycogenolysis, debranching enzymes can synthesize alpha (1-->4) linkages -
Answer-False
The majority of lactate in the avg human body is produced in the cardiac muscle -
Answer-false
Hydrogen peroxide is formed during respiration when on electron is transferred to O2 -
Answer-False
, Insulin does not activate every biochemical pathway that leads to the complete
oxidation of glucose - Answer-true
A biochemical reaction that requires ATP input has a delta G'=-33.4 kj/mol. Which one
of the following is most likely to be true - Answer-The biochemical reaction is exergonic
and irreversible
Which of the following enzymes synthesizes ATP using chemical (heat) energy? -
Answer-Pyruvate Kinase
Which of the following enzymes is required to bypass phosphofructokinase-1 when
synthesizing glucose? - Answer-Fructose-1,6-Bisphophatase
Which one of the following enzymes catalyze the synthesis of alpha(1-->4) glucose
linkages - Answer-Glycogen synthase
Which of the following enzymes is not controlled by glucagon - Answer-hexokinase
Which of the following statements is incorrect regarding citrate synthase - Answer-it is
regulated by Acetyl-coA
Which one of the following is NOT a proton pump - Answer-Complex II
How many ATP molecules are produced from one full turn (360 degrees) of the gamma
subunit - Answer-3
which one of the following enzymes does NOT produce glucose as a product - Answer-
alpha-amylase
which of the following statements regarding FADH2 is true - Answer-electrons donated
from one molecule of FADH2 to the respiratory system yields enough energy to
synthesize about 1.5 molecules of ATP
Which one of the following pathways are not a catabolic pathway? - Answer-
Glycogenesis
Which one of the following is the most important regulation site of glycolysis - Answer-
Phosphofructokinase-1
During gluconeogenesis, we convert OAA to malate. Why? - Answer-Malate can be
transported into the cytosol
Which one of the following molecules is the major end product of glycogenolysis -
Answer-Glucose-1-Phosphate
WITH VERIFIED ANSWERS
The composition of a bilayer has been modified to include 10% cholesterol. Which of
the following is true regarding the new properties of the bilayer - Answer-The Tm of the
bilayer has not changed
AND
The rigidity of the cholesterol broadens the transition temperature of the bilayer
A integral membrane protein that is expected to b eon the plasma membrane is instead
found on the cytoplasm. Which of the following would explain this result - Answer-The
SRP is not able to recognize the N-terminal signal sequence
What might occur if the Zn2+ prosthetic group was no longe present in the enzyme
Carboxypeptidase A during a reaction? - Answer-the delta G double dagger would
increase
Anabolic pathways require an energy input to synthesize mroe complex molecules form
less complex molecules - Answer-True
Phosphoenolpyruvate carboxykinase is found within the mitochondria - Answer-false
Fructose-2,6-bisphosphate inactviates fructose-1,6-bisphophatase by directly binding to
the active site of the enzyme (i.e. its a competitive inhibitor) - Answer-false
Malate/Aspartate shuttle is used by the liver to transport two electrons from cytosolic
NADH onto mitochondrial NADH - Answer-True
Succinate dehydrogenase complex draws two electrons from succinate and donates
them to coenzyme Q - Answer-True
Hexokinase phosphorylates glucose so that glucose can not be transported out of the
cell - Answer-true
During glycogenolysis, debranching enzymes can synthesize alpha (1-->4) linkages -
Answer-False
The majority of lactate in the avg human body is produced in the cardiac muscle -
Answer-false
Hydrogen peroxide is formed during respiration when on electron is transferred to O2 -
Answer-False
, Insulin does not activate every biochemical pathway that leads to the complete
oxidation of glucose - Answer-true
A biochemical reaction that requires ATP input has a delta G'=-33.4 kj/mol. Which one
of the following is most likely to be true - Answer-The biochemical reaction is exergonic
and irreversible
Which of the following enzymes synthesizes ATP using chemical (heat) energy? -
Answer-Pyruvate Kinase
Which of the following enzymes is required to bypass phosphofructokinase-1 when
synthesizing glucose? - Answer-Fructose-1,6-Bisphophatase
Which one of the following enzymes catalyze the synthesis of alpha(1-->4) glucose
linkages - Answer-Glycogen synthase
Which of the following enzymes is not controlled by glucagon - Answer-hexokinase
Which of the following statements is incorrect regarding citrate synthase - Answer-it is
regulated by Acetyl-coA
Which one of the following is NOT a proton pump - Answer-Complex II
How many ATP molecules are produced from one full turn (360 degrees) of the gamma
subunit - Answer-3
which one of the following enzymes does NOT produce glucose as a product - Answer-
alpha-amylase
which of the following statements regarding FADH2 is true - Answer-electrons donated
from one molecule of FADH2 to the respiratory system yields enough energy to
synthesize about 1.5 molecules of ATP
Which one of the following pathways are not a catabolic pathway? - Answer-
Glycogenesis
Which one of the following is the most important regulation site of glycolysis - Answer-
Phosphofructokinase-1
During gluconeogenesis, we convert OAA to malate. Why? - Answer-Malate can be
transported into the cytosol
Which one of the following molecules is the major end product of glycogenolysis -
Answer-Glucose-1-Phosphate
