AHN 548 Ob/Gyn Ch 3 Unit 1 Questions And Answers
Trisomy 13 ANS Severe mental retardation, congenital
heart disease, polydactyly, low set
ears, cleft palate, low birth weight.
Trisomy 18 ANS Trisomy E; severe mental retardation,
long narrow skull with prominent
occiput, congenital heart disease, low
set ears, harelip and cleft palate, low
birth weight
Trisomy 18 ANS Dx during gestation: low maternal AFP, low conjucated estriol, low HCG
Trisomy 21 (Down's) ANS increased risk with maternal age; Down Syndrome
Trisomy 21 (Down's) Patho ANS A third # 21 chromosome
Trisomy 21 (Down's) Dx during Gestation ANS Low maternal AFP, low conjugated estiol
and high HCG.
Trisomy 21 (Down's) s/s ANS Microcephaly, flattened nose, protruding tongue, upward
slanted eyes, hypotonia
Prader-Willi Syndrome & Angelman Syndrome ANS 2 Disorders caused when both sets of
chromosomes are from only one parent. Imprinting disorders
True Hermaphroditism ANS Almost all develop female type breasts & many menstruate
(depending on presence/absence of uterus).
Trisomy 13 ANS Severe mental retardation, congenital
heart disease, polydactyly, low set
ears, cleft palate, low birth weight.
Trisomy 18 ANS Trisomy E; severe mental retardation,
long narrow skull with prominent
occiput, congenital heart disease, low
set ears, harelip and cleft palate, low
birth weight
Trisomy 18 ANS Dx during gestation: low maternal AFP, low conjucated estriol, low HCG
Trisomy 21 (Down's) ANS increased risk with maternal age; Down Syndrome
Trisomy 21 (Down's) Patho ANS A third # 21 chromosome
Trisomy 21 (Down's) Dx during Gestation ANS Low maternal AFP, low conjugated estiol
and high HCG.
Trisomy 21 (Down's) s/s ANS Microcephaly, flattened nose, protruding tongue, upward
slanted eyes, hypotonia
Prader-Willi Syndrome & Angelman Syndrome ANS 2 Disorders caused when both sets of
chromosomes are from only one parent. Imprinting disorders
True Hermaphroditism ANS Almost all develop female type breasts & many menstruate
(depending on presence/absence of uterus).
