Bishop: Clinical Chemistry Questions with Answers
What is the molarity for a solution containing 100 g of NaCl made up to 500 mL with distilled water?
Assume a gram molecular weight (from periodic table) of approximately 58 grams.
a. 3.45 M
b. 1.72 M
c. 290 M
d. 5.27 M - correct answers
What is the normality for a solution containing 100 g of NaCl made up to 500 mL with distilled water?
Assume a gram molecular weight (from periodic table) of approximately 58 grams.
a. 3.45
b. 0.86
c. 1.72
d. 6.9 - correct answers
What is the percent (w/v) for a solution containing 100 g of NaCl made up to 500 mL with distilled
water?
a. 20%
b. 5%
c. 29%
d. 58% - correct answers
What is the dilution factor for a solution containing 100 g of NaCl made up to 500 mL with distilled
water?
a. 1:5 or 1/5
b. 5
c. 50 or 1/50
d. 10 - correct answers
What is the value in mg/dL for a solution containing 10 mg of CaCl2 made with 100 mL of distilled water?
a. 10
,b. 100
c. 50
d. Cannot determine without additional information - correct answers
What is the molarity of a solution containing 10
mg of CaCl2 made with 100 mL of distilled water? Assume a gram molecular weight from the periodic
table of approximately 111 grams.
a. 9 × 10-4
b. 1.1 × 10-3
c. 11.1
d. 90 - correct answers
You must make 1L of 0.2M acetic acid(CH3COOH). All you have available is concentrated glacial acetic
acid (assay value, 98%; specific gravity, 1.05 g/mL). It will take ______ milliliters of acetic acid to make
this solution. Assume a gram molecular weight of 60.05 grams.
a. 11.7
b. 1.029
c. 3.42
d. 12.01 - correct answers
What is the hydrogen ion concentration of an acetate buffer having a pH of 4.24?
a. 5.75 × 10-5
b. 1.19 × 10-1
c. 0.62
d. 0.76 × 10-4 - correct answers
Using the Henderson-Hasselbalch equation, give the ratio of salt to weak acid for a Veronal buffer
withapHof8.6andapKa of 7.43.
a. 14.7/1
b. 1/8.6
,c. 1.17/1
d. 1/4.3 - correct answers
The pKa for acetic acid is 4.76. If the concentra- tion of salt is 5 mmol/L and that of acetic acid is 10
mmol/L, what is the expected pH?
a. 4.46
b. 5.06
c. 104
d. 56 - correct answers
The hydrogen ion concentration of a solution is 0.0000937. What is the pH?
a. 4.03
b. 9.37 × 10-5
c. 9.07
d. 8.03 - correct answers
Perform the following conversions:
4×104 mg=___g
1.3×102 mL=____dL
0.02 mL = ____ μL
5×10-3 mL=___μL
5×10-2 L=___mL
4 cm = _____ mm - correct answers
What volume of 14 N H2SO4 is needed to make
250 mL of 3.2 M H2SO4 solution? Assume a gram
molecular weight of 98.08 grams.
a. 114 mL
b. 1.82 mL
, c. 1.75 mL
d. 7 mL - correct answers
A 1:200 dilution of the urine specimen gives a creatinine result of 0.8 mg/dL. The serum value is 1.2
mg/dL. What is the final value of creatinine in mg/dL in the undiluted urine sample?
a. 160
b. 0.8
c. 960
d. 860 - correct answers
A 24-hour urine has a total volume of 1,200 mL. A 1:200 dilution of the urine specimen gives a creatinine
result of 0.8 mg/dL. The serum value is 1.2 mg/dL. What is the result in terms of grams per 24 hours?
a. 1.92
b. 0.08
c. 80
d. 19 - correct answers
A new medical technologist was selecting analyte standards to develop a standard curve for a high-
performance liquid chromatography (HPLC) procedure. This analyte must have a 100% purity level and
must be suitable for HPLC. Which of the following labels would be most appropriate for this procedure?
a. ACS with no impurities listed
b. USP
c. NF
d. CP
e. ACS with impurities listed - correct answers
When selecting quality control reagents for measuring an analyte in urine, the medical technologist
should select:
a. A quality control reagent prepared in a urine matrix.
b. A quality control reagent prepared in a serum matrix.
What is the molarity for a solution containing 100 g of NaCl made up to 500 mL with distilled water?
Assume a gram molecular weight (from periodic table) of approximately 58 grams.
a. 3.45 M
b. 1.72 M
c. 290 M
d. 5.27 M - correct answers
What is the normality for a solution containing 100 g of NaCl made up to 500 mL with distilled water?
Assume a gram molecular weight (from periodic table) of approximately 58 grams.
a. 3.45
b. 0.86
c. 1.72
d. 6.9 - correct answers
What is the percent (w/v) for a solution containing 100 g of NaCl made up to 500 mL with distilled
water?
a. 20%
b. 5%
c. 29%
d. 58% - correct answers
What is the dilution factor for a solution containing 100 g of NaCl made up to 500 mL with distilled
water?
a. 1:5 or 1/5
b. 5
c. 50 or 1/50
d. 10 - correct answers
What is the value in mg/dL for a solution containing 10 mg of CaCl2 made with 100 mL of distilled water?
a. 10
,b. 100
c. 50
d. Cannot determine without additional information - correct answers
What is the molarity of a solution containing 10
mg of CaCl2 made with 100 mL of distilled water? Assume a gram molecular weight from the periodic
table of approximately 111 grams.
a. 9 × 10-4
b. 1.1 × 10-3
c. 11.1
d. 90 - correct answers
You must make 1L of 0.2M acetic acid(CH3COOH). All you have available is concentrated glacial acetic
acid (assay value, 98%; specific gravity, 1.05 g/mL). It will take ______ milliliters of acetic acid to make
this solution. Assume a gram molecular weight of 60.05 grams.
a. 11.7
b. 1.029
c. 3.42
d. 12.01 - correct answers
What is the hydrogen ion concentration of an acetate buffer having a pH of 4.24?
a. 5.75 × 10-5
b. 1.19 × 10-1
c. 0.62
d. 0.76 × 10-4 - correct answers
Using the Henderson-Hasselbalch equation, give the ratio of salt to weak acid for a Veronal buffer
withapHof8.6andapKa of 7.43.
a. 14.7/1
b. 1/8.6
,c. 1.17/1
d. 1/4.3 - correct answers
The pKa for acetic acid is 4.76. If the concentra- tion of salt is 5 mmol/L and that of acetic acid is 10
mmol/L, what is the expected pH?
a. 4.46
b. 5.06
c. 104
d. 56 - correct answers
The hydrogen ion concentration of a solution is 0.0000937. What is the pH?
a. 4.03
b. 9.37 × 10-5
c. 9.07
d. 8.03 - correct answers
Perform the following conversions:
4×104 mg=___g
1.3×102 mL=____dL
0.02 mL = ____ μL
5×10-3 mL=___μL
5×10-2 L=___mL
4 cm = _____ mm - correct answers
What volume of 14 N H2SO4 is needed to make
250 mL of 3.2 M H2SO4 solution? Assume a gram
molecular weight of 98.08 grams.
a. 114 mL
b. 1.82 mL
, c. 1.75 mL
d. 7 mL - correct answers
A 1:200 dilution of the urine specimen gives a creatinine result of 0.8 mg/dL. The serum value is 1.2
mg/dL. What is the final value of creatinine in mg/dL in the undiluted urine sample?
a. 160
b. 0.8
c. 960
d. 860 - correct answers
A 24-hour urine has a total volume of 1,200 mL. A 1:200 dilution of the urine specimen gives a creatinine
result of 0.8 mg/dL. The serum value is 1.2 mg/dL. What is the result in terms of grams per 24 hours?
a. 1.92
b. 0.08
c. 80
d. 19 - correct answers
A new medical technologist was selecting analyte standards to develop a standard curve for a high-
performance liquid chromatography (HPLC) procedure. This analyte must have a 100% purity level and
must be suitable for HPLC. Which of the following labels would be most appropriate for this procedure?
a. ACS with no impurities listed
b. USP
c. NF
d. CP
e. ACS with impurities listed - correct answers
When selecting quality control reagents for measuring an analyte in urine, the medical technologist
should select:
a. A quality control reagent prepared in a urine matrix.
b. A quality control reagent prepared in a serum matrix.
