Lutz's Nutrition 7th ed. ch 15
What effects does vitamin K and vitamin E on warfarin? correct answers Vitamin K
impedes warfarin and vitamin E enhances it.
Phenytoin correct answers Anticonvulsant
a drug to control epileptic seizures, is a folic acid antagonist that competes with the
vitamin for binding sites.
Pharmacokinetic = results in a lower serum level of phenytoin
Pharmocodynamic = if seizure activity increases
*long term use can cause folic acid deficiency.
Type 1 interactions correct answers occur outside the body
ex. In the intravenous or Parenteral Nutrition (PN) solution.
In the syringe where substances are admixed
In tube feeding reservoirs
In the respective tubing
Type 2 interactions correct answers occurs with oral or eternal intake, producing
increased or decreased bio availability of either the drug or nutrient.
Type 2 interaction influencing factors correct answers Food intake
Modification of enzyme activity or transport mechanisms
Complexing or binding of drugs or nutrients so that one or both are unavailable for
absorption
Parenteral Nutrition (PN) correct answers Administration of a nutritional solution into
the vascular system.
*PN is a complex formulation of glucose, amino acids, fat emulsion, electrolytes,
vitamins, and trace elements.
*medications are not usually added to PN, but commonly added ones are insulin and
heparin.
*prolonged exposure to these meds to the PN solution can result in incompatibility
reactions such as forming precipitates, discoloration, and degradation of nutrients or
medication.
delayed absorption correct answers some drugs take longer to be absorbed if ingested
with food.
decreased absorption correct answers Food can decrease the rate and extent of
absorption. Reducing the rate of absorption delays the onset of peak effects. Reducing
the extent of absorption reduces the intended effect of the medication.
What effects does vitamin K and vitamin E on warfarin? correct answers Vitamin K
impedes warfarin and vitamin E enhances it.
Phenytoin correct answers Anticonvulsant
a drug to control epileptic seizures, is a folic acid antagonist that competes with the
vitamin for binding sites.
Pharmacokinetic = results in a lower serum level of phenytoin
Pharmocodynamic = if seizure activity increases
*long term use can cause folic acid deficiency.
Type 1 interactions correct answers occur outside the body
ex. In the intravenous or Parenteral Nutrition (PN) solution.
In the syringe where substances are admixed
In tube feeding reservoirs
In the respective tubing
Type 2 interactions correct answers occurs with oral or eternal intake, producing
increased or decreased bio availability of either the drug or nutrient.
Type 2 interaction influencing factors correct answers Food intake
Modification of enzyme activity or transport mechanisms
Complexing or binding of drugs or nutrients so that one or both are unavailable for
absorption
Parenteral Nutrition (PN) correct answers Administration of a nutritional solution into
the vascular system.
*PN is a complex formulation of glucose, amino acids, fat emulsion, electrolytes,
vitamins, and trace elements.
*medications are not usually added to PN, but commonly added ones are insulin and
heparin.
*prolonged exposure to these meds to the PN solution can result in incompatibility
reactions such as forming precipitates, discoloration, and degradation of nutrients or
medication.
delayed absorption correct answers some drugs take longer to be absorbed if ingested
with food.
decreased absorption correct answers Food can decrease the rate and extent of
absorption. Reducing the rate of absorption delays the onset of peak effects. Reducing
the extent of absorption reduces the intended effect of the medication.
