SCI 225
PATHOPHYSIOLOGY
Week 10: Muscoskeletal
Disorders
CONTENT REVIEW EXAM
©Nightingale 2024/2025
,1. Multiple Choice: Which hormone is primarily involved in the
regulation of serum calcium and is implicated in various
musculoskeletal disorders?
a) Estrogen
b) Insulin
c) Parathyroid hormone
d) Cortisol
Correct Answer: c) Parathyroid hormone
Rationale: Parathyroid hormone regulates calcium levels in the
blood, with low levels leading to hypocalcemia and high levels to
hypercalcemia, both of which can affect bone health.
2. Fill-in-the-Blank: __________ is the term used to describe the
death of bone tissue due to a lack of blood supply, often leading to
joint pain and stiffness.
Correct Answer: Avascular necrosis
Rationale: Avascular necrosis can lead to the collapse of the bone
structure and is a serious condition that can result from trauma,
long-term steroid use, or excessive alcohol consumption.
3. True/False: Osteoporosis is an inflammatory condition that
primarily affects the joints.
Correct Answer: False
©Nightingale 2024/2025
, Rationale: Osteoporosis is a metabolic bone disease
characterized by decreased bone density and increased fracture
risk, not an inflammatory joint disease.
4. Multiple Response: Select all that apply. Which of the following
are common signs and symptoms of rheumatoid arthritis?
a) Symmetrical joint swelling
b) Morning stiffness lasting more than an hour
c) High-grade fever
d) Subcutaneous nodules
Correct Answers: a) Symmetrical joint swelling, b) Morning
stiffness lasting more than an hour, d) Subcutaneous nodules
Rationale: Rheumatoid arthritis is characterized by symmetrical
joint swelling, prolonged morning stiffness, and subcutaneous
nodules, among other symptoms. High-grade fever is not typically
associated with it.
5. Multiple Choice: What is the gold standard diagnostic test for
osteoarthritis?
a) MRI
b) X-ray
c) CT scan
d) Ultrasound
©Nightingale 2024/2025
PATHOPHYSIOLOGY
Week 10: Muscoskeletal
Disorders
CONTENT REVIEW EXAM
©Nightingale 2024/2025
,1. Multiple Choice: Which hormone is primarily involved in the
regulation of serum calcium and is implicated in various
musculoskeletal disorders?
a) Estrogen
b) Insulin
c) Parathyroid hormone
d) Cortisol
Correct Answer: c) Parathyroid hormone
Rationale: Parathyroid hormone regulates calcium levels in the
blood, with low levels leading to hypocalcemia and high levels to
hypercalcemia, both of which can affect bone health.
2. Fill-in-the-Blank: __________ is the term used to describe the
death of bone tissue due to a lack of blood supply, often leading to
joint pain and stiffness.
Correct Answer: Avascular necrosis
Rationale: Avascular necrosis can lead to the collapse of the bone
structure and is a serious condition that can result from trauma,
long-term steroid use, or excessive alcohol consumption.
3. True/False: Osteoporosis is an inflammatory condition that
primarily affects the joints.
Correct Answer: False
©Nightingale 2024/2025
, Rationale: Osteoporosis is a metabolic bone disease
characterized by decreased bone density and increased fracture
risk, not an inflammatory joint disease.
4. Multiple Response: Select all that apply. Which of the following
are common signs and symptoms of rheumatoid arthritis?
a) Symmetrical joint swelling
b) Morning stiffness lasting more than an hour
c) High-grade fever
d) Subcutaneous nodules
Correct Answers: a) Symmetrical joint swelling, b) Morning
stiffness lasting more than an hour, d) Subcutaneous nodules
Rationale: Rheumatoid arthritis is characterized by symmetrical
joint swelling, prolonged morning stiffness, and subcutaneous
nodules, among other symptoms. High-grade fever is not typically
associated with it.
5. Multiple Choice: What is the gold standard diagnostic test for
osteoarthritis?
a) MRI
b) X-ray
c) CT scan
d) Ultrasound
©Nightingale 2024/2025
