SCI 225
PATHOPHYSIOLOGY
Week 7: Neurological Disorders
CONTENT REVIEW EXAM
©Nightingale 2024/2025
,1. Multiple Choice: Which neurotransmitter is primarily involved
in the pathophysiology of Parkinson's Disease?
a) Acetylcholine
b) Dopamine
c) Serotonin
d) GABA
Correct Answer: b) Dopamine
Rationale: Parkinson's Disease is characterized by the
degeneration of dopamine-producing neurons in the substantia
nigra, leading to the hallmark symptoms of tremors, rigidity, and
bradykinesia.
2. Fill-in-the-Blank: __________ is the term used to describe the
death of brain tissue resulting from ischemia.
Correct Answer: Infarction
Rationale: An infarction occurs when blood flow is interrupted,
leading to tissue death. In the brain, this can result in a stroke,
causing various neurological deficits depending on the area
affected.
3. True/False: Multiple Sclerosis is an autoimmune disorder that
affects the peripheral nervous system.
©Nightingale 2024/2025
, Correct Answer: False
Rationale: Multiple Sclerosis is an autoimmune disorder that
primarily affects the central nervous system, not the peripheral
nervous system, leading to demyelination and disruption of nerve
signal transmission.
4. Multiple Response: Select all that apply. Which of the following
are potential complications of a subarachnoid hemorrhage?
a) Vasospasm
b) Hydrocephalus
c) Seizures
d) Hypertension
Correct Answers: a) Vasospasm, b) Hydrocephalus, c) Seizures
Rationale: A subarachnoid hemorrhage can lead to several
complications, including vasospasm (narrowing of blood vessels),
hydrocephalus (accumulation of cerebrospinal fluid), and seizures.
Hypertension is a risk factor, not a complication.
5. Multiple Choice: What is the primary pathological feature of
Alzheimer's Disease?
a) Lewy bodies
b) Neurofibrillary tangles
c) Spongiform changes
©Nightingale 2024/2025
PATHOPHYSIOLOGY
Week 7: Neurological Disorders
CONTENT REVIEW EXAM
©Nightingale 2024/2025
,1. Multiple Choice: Which neurotransmitter is primarily involved
in the pathophysiology of Parkinson's Disease?
a) Acetylcholine
b) Dopamine
c) Serotonin
d) GABA
Correct Answer: b) Dopamine
Rationale: Parkinson's Disease is characterized by the
degeneration of dopamine-producing neurons in the substantia
nigra, leading to the hallmark symptoms of tremors, rigidity, and
bradykinesia.
2. Fill-in-the-Blank: __________ is the term used to describe the
death of brain tissue resulting from ischemia.
Correct Answer: Infarction
Rationale: An infarction occurs when blood flow is interrupted,
leading to tissue death. In the brain, this can result in a stroke,
causing various neurological deficits depending on the area
affected.
3. True/False: Multiple Sclerosis is an autoimmune disorder that
affects the peripheral nervous system.
©Nightingale 2024/2025
, Correct Answer: False
Rationale: Multiple Sclerosis is an autoimmune disorder that
primarily affects the central nervous system, not the peripheral
nervous system, leading to demyelination and disruption of nerve
signal transmission.
4. Multiple Response: Select all that apply. Which of the following
are potential complications of a subarachnoid hemorrhage?
a) Vasospasm
b) Hydrocephalus
c) Seizures
d) Hypertension
Correct Answers: a) Vasospasm, b) Hydrocephalus, c) Seizures
Rationale: A subarachnoid hemorrhage can lead to several
complications, including vasospasm (narrowing of blood vessels),
hydrocephalus (accumulation of cerebrospinal fluid), and seizures.
Hypertension is a risk factor, not a complication.
5. Multiple Choice: What is the primary pathological feature of
Alzheimer's Disease?
a) Lewy bodies
b) Neurofibrillary tangles
c) Spongiform changes
©Nightingale 2024/2025
