ADVANCED PHARMACOLOGY FINAL
EXAM REVIEW QUESTIONS AND
ANSWERS
Whysaresnitrate-
freesperiodsseverys24shourssnecessarysforsthespatientsonsnitroglycerinstherapy?s-
sans✔✔Tosinhibitsthesdevelopmentsofstolerance
Whatsdoessaslowslevelsofsthyroid-stimulatingshormonesindicate?s-sans✔✔Hyperthroidism
WhatswouldsbesthesbestsoptionstostreatsasnewlysdiagnosedspatientswithsaslowsTSHslevelswith
?s-sans✔✔Propanolols(Inderal)
Spironoaldactones(Aldactone)shasswhatsmechanismsofsactions(MOA)?s-
sans✔✔Aldosteronesantagonist
Heparinsexertssitsstherapeuticsactionsbyswhat?s-
sans✔✔Upregulatingsthesactivitysofsonesofsthesbody'ssnaturalsanticoagulantsmolecules,santi
thrombinsIII
Whatsphysiologicsactionshappensswhensthesoffendingsdrugsissadministeredsduringsansanap
hylacticsreaction.s-sans✔✔Mastscellssliberateslargesdosessofshistamine.
Whatsarestwossystemicspsoriasissmedications?s-sans✔✔Photo-
therapysandstopicalscorticosteroids
Whatsissthesfirstschoicesofsdrugstherapysforsthesmajoritysofspatientsswithsuncomplicatedsstag
esIshypertension?s-sans✔✔Thiazidesdiuretics
Whatsisstheseffectsofscardiacsglycosides?s-
sans✔✔Digitalissglycosidesshavesasnegativeschronotropicseffectsonsthescardiacsmusclescell
s.
Amenorrheasissthesmostscommonssideseffectsofswhichsbirthscontrolsmedication?s-
sans✔✔Medroxyprogesterones(Depo-Provera)
Whatsissansanti-hypertensivesagentswhichscompetesswithsepinephrinesforsavailablesbeta-
receptorssites?s-sans✔✔Atenolols(Tenormin)
, Whatstypesofsactionsdoessnitratesshavesonsthesbody?s-
sans✔✔Reductionsinssystemicsvenousstone.
Whatsissthesrecommendedslevelsofslow-
densityslipoproteinscholesterols(LDL)sforspatientsswithsknownscoronarysarterysdisease?s-
sans✔✔100mg/dlsorsless.
WhatsissthesMOAsofsgroupsIVsanti-dysrhythmiasdrugs?s-
sans✔✔Depressingsphases4sdepolarizationsandslengtheningsphasess1sands2srepolarization
.
Whichsdrugstherapysshouldsbesusedstoslowersthesserumsconcentrationsofsthyroidshormoness
andsre-establishseumetabolicsstatesinsaspatientswithsGraves'sdisease?s-sans✔✔Anti-
thyroidsdrugs.
WhichstypesofsdiureticswouldsbesusedsforsasstagesIshypertensionsinsaspatientswithsrenalsinsuf
ficiency?s-sans✔✔Loopsdiuretic.
Whatsdrugsshouldsbesconsideredsassfirst-
linestherapysforsasclientswithshypertensionsandsheartsfailure?s-sans✔✔Enalaprils(Vasotec)
Whichsdrugsissconsideredssafesforshypertensionstreatmentsduringspregnancy?s-
sans✔✔Methyldopas(Aldomet)
Whatsdrugswillsreducesafterloadsbecausesitsissansalpha-adrenergicsblocker?s-
sans✔✔Prazosins(Minipress)
Whatsissansexpectedseffectsofsthesusesofsasbeta-adrenergicsblockerstoscontrolsangina?s-
sans✔✔Reducedsforcesofscardiacscontraction.
WhatssideseffectsshouldsbesmonitoredscloselysinstheselderlyswhenstakingsMetformins(Gluco
phage)sforstypes2sdiabetes?s-sans✔✔Lacticsacidosis.
Whatsissthesprimarysrolesofscytochromesp-450sinsthesliver?s-
sans✔✔Deactivatesandsdetoxifysmedicationssandsotherssubstances.
WhatsissascomponentsofsVitaminsK-dependentsclottingsfactors?s-sans✔✔Prothrombin
HowsaresIVsmorphinesandsnitroglycerinsbeneficialsinsacutesheartsfailure?s-
sans✔✔Decreasespreload.
Whatsissthespurposesofsadministeringsasvasodilatingsdrugstosaspatientsinsheartsfailure?s-
sans✔✔Decreasesafterload.
EXAM REVIEW QUESTIONS AND
ANSWERS
Whysaresnitrate-
freesperiodsseverys24shourssnecessarysforsthespatientsonsnitroglycerinstherapy?s-
sans✔✔Tosinhibitsthesdevelopmentsofstolerance
Whatsdoessaslowslevelsofsthyroid-stimulatingshormonesindicate?s-sans✔✔Hyperthroidism
WhatswouldsbesthesbestsoptionstostreatsasnewlysdiagnosedspatientswithsaslowsTSHslevelswith
?s-sans✔✔Propanolols(Inderal)
Spironoaldactones(Aldactone)shasswhatsmechanismsofsactions(MOA)?s-
sans✔✔Aldosteronesantagonist
Heparinsexertssitsstherapeuticsactionsbyswhat?s-
sans✔✔Upregulatingsthesactivitysofsonesofsthesbody'ssnaturalsanticoagulantsmolecules,santi
thrombinsIII
Whatsphysiologicsactionshappensswhensthesoffendingsdrugsissadministeredsduringsansanap
hylacticsreaction.s-sans✔✔Mastscellssliberateslargesdosessofshistamine.
Whatsarestwossystemicspsoriasissmedications?s-sans✔✔Photo-
therapysandstopicalscorticosteroids
Whatsissthesfirstschoicesofsdrugstherapysforsthesmajoritysofspatientsswithsuncomplicatedsstag
esIshypertension?s-sans✔✔Thiazidesdiuretics
Whatsisstheseffectsofscardiacsglycosides?s-
sans✔✔Digitalissglycosidesshavesasnegativeschronotropicseffectsonsthescardiacsmusclescell
s.
Amenorrheasissthesmostscommonssideseffectsofswhichsbirthscontrolsmedication?s-
sans✔✔Medroxyprogesterones(Depo-Provera)
Whatsissansanti-hypertensivesagentswhichscompetesswithsepinephrinesforsavailablesbeta-
receptorssites?s-sans✔✔Atenolols(Tenormin)
, Whatstypesofsactionsdoessnitratesshavesonsthesbody?s-
sans✔✔Reductionsinssystemicsvenousstone.
Whatsissthesrecommendedslevelsofslow-
densityslipoproteinscholesterols(LDL)sforspatientsswithsknownscoronarysarterysdisease?s-
sans✔✔100mg/dlsorsless.
WhatsissthesMOAsofsgroupsIVsanti-dysrhythmiasdrugs?s-
sans✔✔Depressingsphases4sdepolarizationsandslengtheningsphasess1sands2srepolarization
.
Whichsdrugstherapysshouldsbesusedstoslowersthesserumsconcentrationsofsthyroidshormoness
andsre-establishseumetabolicsstatesinsaspatientswithsGraves'sdisease?s-sans✔✔Anti-
thyroidsdrugs.
WhichstypesofsdiureticswouldsbesusedsforsasstagesIshypertensionsinsaspatientswithsrenalsinsuf
ficiency?s-sans✔✔Loopsdiuretic.
Whatsdrugsshouldsbesconsideredsassfirst-
linestherapysforsasclientswithshypertensionsandsheartsfailure?s-sans✔✔Enalaprils(Vasotec)
Whichsdrugsissconsideredssafesforshypertensionstreatmentsduringspregnancy?s-
sans✔✔Methyldopas(Aldomet)
Whatsdrugswillsreducesafterloadsbecausesitsissansalpha-adrenergicsblocker?s-
sans✔✔Prazosins(Minipress)
Whatsissansexpectedseffectsofsthesusesofsasbeta-adrenergicsblockerstoscontrolsangina?s-
sans✔✔Reducedsforcesofscardiacscontraction.
WhatssideseffectsshouldsbesmonitoredscloselysinstheselderlyswhenstakingsMetformins(Gluco
phage)sforstypes2sdiabetes?s-sans✔✔Lacticsacidosis.
Whatsissthesprimarysrolesofscytochromesp-450sinsthesliver?s-
sans✔✔Deactivatesandsdetoxifysmedicationssandsotherssubstances.
WhatsissascomponentsofsVitaminsK-dependentsclottingsfactors?s-sans✔✔Prothrombin
HowsaresIVsmorphinesandsnitroglycerinsbeneficialsinsacutesheartsfailure?s-
sans✔✔Decreasespreload.
Whatsissthespurposesofsadministeringsasvasodilatingsdrugstosaspatientsinsheartsfailure?s-
sans✔✔Decreasesafterload.
