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Biol 436 Practice Test Questions and Correct Answers

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Sarcomere -the basic unit of muscle contraction -Lined up to form the long structure (myofibril) -2 major elements of sarcomere -Actin (thin filament)= stabilized by tropomyosin, activated by troponin -myosin (thick filament) -Stabilized by titan and Nebulin -Z disk on either end, shared with next sarcomere over Nebulin anchors each thin actin filaments together at the center of the sarcomere Titan -Largest protein known to be made in cells. -Extends from Z-disk and tethers the thick filaments to the Z-disk Actin -Thin filament of sarcomere -Form a double stranded pearl necklace -They have a binding site for myosin Myosin -Thick Filaments of sarcomere Head consists of -Actin binding site that binds with myosin binding site on thin filaments (Actin) (accomplishes cross-bridging) -Myosin ATPase site (takes ATP and hydrolyzes it to ADP) Troponin protein complex that can bind calcium, which causes it to change shape and roll the tropomyosin out of the way and exposes the myosin binding site on actin. Tropomyosin Wraps around actin molecules which stabilizes the structure and covers up the myosin binding site in a resting state. Muscle Fiber (muscle cells) Consists of sarcolemma (outside membrane) T-Tubules (how AP is carried into the interior of muscle fiber) Sarcoplasm=fluid inside muscle fiber Rigor Mortis when myosin head group is attached to the actin subunits, requires binding of ATP to release the 2 molecules. Rigor Mortis= no more ATP

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Biol 436 Practice Test Questions and
Correct Answers
Sarcomere ✅-the basic unit of muscle contraction
-Lined up to form the long structure (myofibril)
-2 major elements of sarcomere
-Actin (thin filament)= stabilized by tropomyosin, activated by troponin
-myosin (thick filament)
-Stabilized by titan and Nebulin
-Z disk on either end, shared with next sarcomere over

Nebulin ✅anchors each thin actin filaments together at the center of the sarcomere

Titan ✅-Largest protein known to be made in cells.
-Extends from Z-disk and tethers the thick filaments to the Z-disk

Actin ✅-Thin filament of sarcomere
-Form a double stranded pearl necklace
-They have a binding site for myosin

Myosin ✅-Thick Filaments of sarcomere
Head consists of
-Actin binding site that binds with myosin binding site on thin filaments (Actin)
(accomplishes cross-bridging)
-Myosin ATPase site (takes ATP and hydrolyzes it to ADP)

Troponin ✅protein complex that can bind calcium, which causes it to change shape
and roll the tropomyosin out of the way and exposes the myosin binding site on actin.

Tropomyosin ✅Wraps around actin molecules which stabilizes the structure and
covers up the myosin binding site in a resting state.

Muscle Fiber ✅(muscle cells)
Consists of sarcolemma (outside membrane)
T-Tubules (how AP is carried into the interior of muscle fiber)
Sarcoplasm=fluid inside muscle fiber

Rigor Mortis ✅when myosin head group is attached to the actin subunits, requires
binding of ATP to release the 2 molecules.
Rigor Mortis= no more ATP

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