First Aid Pathology: Carcinogens
1. Aspergillus (produces aflatoxins), hepatocellular carcinoma: High levels
of aflatoxins are detected in a patient with a liver mass. For which infectious
organism should testing be strongly considered? What cancer is this associated
with?
2. Chemical plant worker, vinyl chloride: A patient of yours is found to have
angiosarcoma of the liver. What was this patient's most likely occupation? What
carcinogen do they work around?
3. Centrilobular necrosis and fatty change in the liver: Exposure to carbon
tetrachloride can cause what pathology?
4. Nitrosamines: Smoked foods often have this chemical that is associated
with an increased risk of *stomach cancer.*
5. Lung cancers, laryngeal squamous cell carcinoma, renal cell
carcinoma, bladder cancer, pancreatic adenocarcinoma, esophageal
cancers: Name 5 cancers that are associated with the carcinogenic effects of
cigarette smoke.
6. Asbestos, bronchogenic carcinoma: What chemical carcinogen is
associated with mesothelioma and bronchogenic carcinoma? Which one occurs
more commonly?
7. Squamous cell carcinoma of the skin, lung cancer, angiosarcoma of the
liver: Arsenic exposure is associated with what three types of carcinoma?
8. Aromatic amines (e.g., benzidine, 2-naphthylamine): A patient has gross
hematuria. You find a transitional cell carcinoma. What type of chemical is
classically associated with this malignancy?
9. Blood cancers (leukemia): A woman's breast cancer is fully treated with an
alkylating agent. For which other cancer type should lifelong screening be done?
10. Hepatocellular carcinoma and squamous cell carcinoma of the
esophagus: The risk for what two carcinomas can be increased by drinking
ethanol?
11. Lung cancer: A woman worked in a factory that made radium dial watches
that emitted radon. For what type of malignancy did this increase her risk?
12. Papillary thyroid carcinoma: A patient is exposed to ionizing radiation in a
work accident. For what specific malignancy does this increase his risk?
1. Aspergillus (produces aflatoxins), hepatocellular carcinoma: High levels
of aflatoxins are detected in a patient with a liver mass. For which infectious
organism should testing be strongly considered? What cancer is this associated
with?
2. Chemical plant worker, vinyl chloride: A patient of yours is found to have
angiosarcoma of the liver. What was this patient's most likely occupation? What
carcinogen do they work around?
3. Centrilobular necrosis and fatty change in the liver: Exposure to carbon
tetrachloride can cause what pathology?
4. Nitrosamines: Smoked foods often have this chemical that is associated
with an increased risk of *stomach cancer.*
5. Lung cancers, laryngeal squamous cell carcinoma, renal cell
carcinoma, bladder cancer, pancreatic adenocarcinoma, esophageal
cancers: Name 5 cancers that are associated with the carcinogenic effects of
cigarette smoke.
6. Asbestos, bronchogenic carcinoma: What chemical carcinogen is
associated with mesothelioma and bronchogenic carcinoma? Which one occurs
more commonly?
7. Squamous cell carcinoma of the skin, lung cancer, angiosarcoma of the
liver: Arsenic exposure is associated with what three types of carcinoma?
8. Aromatic amines (e.g., benzidine, 2-naphthylamine): A patient has gross
hematuria. You find a transitional cell carcinoma. What type of chemical is
classically associated with this malignancy?
9. Blood cancers (leukemia): A woman's breast cancer is fully treated with an
alkylating agent. For which other cancer type should lifelong screening be done?
10. Hepatocellular carcinoma and squamous cell carcinoma of the
esophagus: The risk for what two carcinomas can be increased by drinking
ethanol?
11. Lung cancer: A woman worked in a factory that made radium dial watches
that emitted radon. For what type of malignancy did this increase her risk?
12. Papillary thyroid carcinoma: A patient is exposed to ionizing radiation in a
work accident. For what specific malignancy does this increase his risk?
