ASCP EXAM 4 QUESTIONS AND
ANSWERS WITH SOLUTIONS 2024
Histiocytes with intracytoplasmic hemosiderin pigment seen in sputum specimens are called: - ANSWER
Heart failure cells
Casts of insipissated muscus seen in sputum specimens best describes: - ANSWER Curschmann's spirals
What is lined by pseudostratified columnar epithelium? - ANSWER Bronchus
In a sputum specimen, enlarged macrophages with vacuolated, lacy cytoplasm were seen. Patient most
likely to have: - ANSWER Lipid Pneumonia
The sputum of a patient with asthma may show an increased number of: - ANSWER Eosinophils
What is most suggestive of a granulomatous inflammation? - ANSWER Epithelioid histiocytes
Caseating necrosis is generally associated with: - ANSWER Tuberculosis
A fine needle aspiration of a lung nodule from a 61 yr old woman with a one year history of a productive
cough and progressive weight loss revealed:
-clusters of small uniform cells
-hyperchromatic nuclei
-neurosecretory granules on immunocytochemistry
Interpretation is: - ANSWER Carcinoid tumor
A fine needle aspiration of the lung of a 43 yr old woman with multiple lung nodules contains:
-monotonous large sheets of cells with abundant, lacy cytoplasm
-round to oval nuclei that vary in size
, -evenly distributed, hyperchromatic chromatin
-prominent nucleoli
Consistent with: - ANSWER Renal cell carcinoma
Numerous papillary groupings with minimal pleomorphism and psammoma bodies were found in a
sputum from a 55 yr old man with bilateral diffuse infiltrates and copius mucoid sputum production.
Consistent with: - ANSWER Bronchioloalveolar carcinoma
Cells from small cell carcinoma may be most difficult to differentiate from: - ANSWER Malignant
lymphoma
Malignant squamous cells seen in sputum specimens are derived from a lesion that is usually: - ANSWER
Centrally located
A sputum sample contained several spherical thick walled structures measuring 20-60 m in diameter.
Rare arthrospores are also noted. The patient is infected with: - ANSWER coccidioides
A thick 45 degree branching fungus with brown, septate hyphae found in a sputum specimen would
most likely be: - ANSWER Aspergillus species
The presence of small, 1-2m budding organisms within the cytoplasm of pulmonary macrophages best
describes: - ANSWER Histoplasma capsulatum
What would be associated with flu like symptoms following a vacation that included a camping trip in
Arizona and New Mexico? - ANSWER Coccidiomycosis
In the Papanicolaou staining method, nucleoli are stained with: - ANSWER Eosin
In order for carcinoma in situ to become invasive, the: - ANSWER Basement membrane must be
transversed
ANSWERS WITH SOLUTIONS 2024
Histiocytes with intracytoplasmic hemosiderin pigment seen in sputum specimens are called: - ANSWER
Heart failure cells
Casts of insipissated muscus seen in sputum specimens best describes: - ANSWER Curschmann's spirals
What is lined by pseudostratified columnar epithelium? - ANSWER Bronchus
In a sputum specimen, enlarged macrophages with vacuolated, lacy cytoplasm were seen. Patient most
likely to have: - ANSWER Lipid Pneumonia
The sputum of a patient with asthma may show an increased number of: - ANSWER Eosinophils
What is most suggestive of a granulomatous inflammation? - ANSWER Epithelioid histiocytes
Caseating necrosis is generally associated with: - ANSWER Tuberculosis
A fine needle aspiration of a lung nodule from a 61 yr old woman with a one year history of a productive
cough and progressive weight loss revealed:
-clusters of small uniform cells
-hyperchromatic nuclei
-neurosecretory granules on immunocytochemistry
Interpretation is: - ANSWER Carcinoid tumor
A fine needle aspiration of the lung of a 43 yr old woman with multiple lung nodules contains:
-monotonous large sheets of cells with abundant, lacy cytoplasm
-round to oval nuclei that vary in size
, -evenly distributed, hyperchromatic chromatin
-prominent nucleoli
Consistent with: - ANSWER Renal cell carcinoma
Numerous papillary groupings with minimal pleomorphism and psammoma bodies were found in a
sputum from a 55 yr old man with bilateral diffuse infiltrates and copius mucoid sputum production.
Consistent with: - ANSWER Bronchioloalveolar carcinoma
Cells from small cell carcinoma may be most difficult to differentiate from: - ANSWER Malignant
lymphoma
Malignant squamous cells seen in sputum specimens are derived from a lesion that is usually: - ANSWER
Centrally located
A sputum sample contained several spherical thick walled structures measuring 20-60 m in diameter.
Rare arthrospores are also noted. The patient is infected with: - ANSWER coccidioides
A thick 45 degree branching fungus with brown, septate hyphae found in a sputum specimen would
most likely be: - ANSWER Aspergillus species
The presence of small, 1-2m budding organisms within the cytoplasm of pulmonary macrophages best
describes: - ANSWER Histoplasma capsulatum
What would be associated with flu like symptoms following a vacation that included a camping trip in
Arizona and New Mexico? - ANSWER Coccidiomycosis
In the Papanicolaou staining method, nucleoli are stained with: - ANSWER Eosin
In order for carcinoma in situ to become invasive, the: - ANSWER Basement membrane must be
transversed
