Bilateral generalized seizure is induced in ECT correct answers For both the beneficial and
adverse effects of ECT, this is induced. We know ECT has worked.
Raises the seizure threshold during ECT. Plasma amino acid (neuro)transmitters are blocked.
correct answers Increase in gamma-aminobutyric acid (GABA) transmission and receptor
antagonism has been observed with ECT.
correct answers ECT may also lead to an increase of endogenous opioids, which may also have
anticonvulsant properties
ECT has been an effective treatment option in severe and treatment resistant depression. MOA is
still unknown. PET studied the effects of ECT. correct answers Reduced glucose metabolism
after ECT in bilateral anterior and posterior frontal areas represented the most consistent
findings.
Psychomotor agitation : psychosis causing anxiety contributing to psychomotor disturbance.
correct answers PSYCHOTIC DEPRESSIVES may have inability to relax/restlessness or sit still.
They may rock, fidget, or move their legs a lot, for example.
Indication of ECT correct answers Symptoms which are extremes of psychiatric conditions
Indications of ECT in Major Depressive Disorder : extremes of MDD. correct answers
Depression with Suicidal ideation, Psychotic depression, Melancholic depression , Depression
with Catatonia, Atypical depression, not eating and nutritionally compromised.
Indications of ECT in Schizophrenia : extremes of schizophrenia correct answers Acute
schizophrenia, treatment-resistant psychosis, depression with suicidal ideation or catatonic
behavior or inanition.
Inanition correct answers Exhausted state/ fatigue due to prolonged undernutrition; starvation
Other psychiatric conditions which may present in extremes indicated for ECT correct answers
Schizophreniform disorder and schizoaffective disorder
Schizophreniform disorder : Development of schizophrenia or prodrome is several years or is
CHRONIC. correct answers Symptoms of schizophrenia, but it is distinguished from that
condition by its shorter duration, which is at least 1 month but less than 6 months.
Annals of clinical psychiatry 2008. But the treatment response is limited by the chronicity of
catatonia. correct answers ECT has been effective in the treatment of catatonia
American journal of psychiatry 2007, ECT indication correct answers Neuroleptic malignant
syndrome