and CORRECT Answers
bioavailability of SC, IM and IV - CORRECT ANSWER- 1 = 100%
8 factors that make a medication order legal and valid - CORRECT ANSWER- patient name,
date, drug, dose, frequency, route, prescriber name and signature
swiss cheese model - CORRECT ANSWER- systems have multiple layers that should remain
intact - active and latent conditions
mane - CORRECT ANSWER- Morning
nocte - CORRECT ANSWER- night
IM - CORRECT ANSWER- Intramuscular
IV - CORRECT ANSWER- Intravenous
NEB - CORRECT ANSWER- Nebuliser
tds - CORRECT ANSWER- Three times a day
prn - CORRECT ANSWER- As required
stat - CORRECT ANSWER- Immediately
g - CORRECT ANSWER- Gram
mmol - CORRECT ANSWER- Millimole
,qid - CORRECT ANSWER- Four times a day
mL - CORRECT ANSWER- millilitre
microgram - CORRECT ANSWER- microgram
subcut - CORRECT ANSWER- subcutaneous
PO - CORRECT ANSWER- orally
prn - CORRECT ANSWER- when required
bd - CORRECT ANSWER- twice a day
4 clinical trial phases and stages of medication approval - CORRECT ANSWER- PHASE 0
HUMAN PHARMACOLOGY: assess pharmacokinetics - does it behave as expected,
microdosing 10-15 healthy volunteers. PHASE 1: HUMAN PHARMACOLOGY: safety and
tolerance - work out doses, 10-100 heatlhy volunteers or volun. w target illness. PHASE 2:
THERAPEUTIC EXPLORATORY: efficacy and safety - how well it works and safety, 100-
300 volunteers w targget illness. PHASE 3 THERAPEUTIC CONFIRMATORY: safety and
efficacy or effectiveness - more info on how well it works and how safe it is, 700-7000
volunteers w illness
3 stages of medication approval - CORRECT ANSWER- 1. Approval by TGA: approved for
sale if phase 3 meets standards. 2. PBS subsidy: approved if it is as good or better than other
meds w same effect and acceptable price. 3. Clinical Phase: post marketing surveillance or
resolution of treatment uncertanties, safety monitory
generic name - CORRECT ANSWER- shortened chemical compound name
brand name - CORRECT ANSWER- given by drug company - panadol
, schedules that apply to medications - CORRECT ANSWER- 2: pharmacy medications, 3:
pharmacy only. 4: prescription only. 8: controlled drug
S8 drug - storage, nursing actions and example - CORRECT ANSWER- locked cupboard on
wall of treatment room, two nurses to administer, keys kept with RN in charge - morphine
Schedules - CORRECT ANSWER- tells us how the public and healthcare professionals can
access medications
first pass effect - CORRECT ANSWER- some drugs may be extensively metabolised before
reaching body
High Risk Medications (APINCHS) - CORRECT ANSWER- Antimicrobials
Potassium
Insulin
Narcotics
Chemotherapeutic agents
Heparin
Systems
bioavailbaility of oral meds and why - CORRECT ANSWER- less than one because partially
metabolised
pharmacokinetics - CORRECT ANSWER- what body does to the drug
pharmacodynamics - CORRECT ANSWER- what drug does to the body
4 processes of pharmacokinetics - CORRECT ANSWER- 1. Absorption: route of
administration determines its absorption and therefore availability. 2. Metabolism: site is
liver. 3. Distribution: through plasma and 4. Excretion: in kidneys
% used in calculating half life - CORRECT ANSWER- 100%, 50%, 25%, 12.5%