MRCP 1- Respiratory review 2024
COPD: investigation and diagnosis
post-bronchodilator spirometry to demonstrate airflow obstruction: FEV1/FVC
ratio less than 70% - Post-bronchodilator FEV1/FVC < 0.7
FEV1 (of predicted) > 80%
Severity Stage 1 - Mild**
Post-bronchodilator FEV1/FVC < 0.7
FEV1 (of predicted) 50-79%
Severity Stage 2 - Moderate
Post-bronchodilator FEV1/FVC < 0.7
FEV1 (of predicted) 30-49%
Severity Stage 3 - severe
Post-bronchodilator FEV1/FVC < 0.7
FEV1 (of predicted) <30%
Severity Stage4 - very severe
,MRCP 1- Respiratory review 2024
Basal atelectasis should be suspected in the presentation of dyspnoea and
hypoxaemia 72 hours post operatively - Basal atelectasis should be suspected in
the presentation of dyspnoea and hypoxaemia 72 hours post operatively
Isocyanates are the most common cause of occupational asthma - Isocyanates are
the most common cause of occupational asthma
carbon monoxide transfer factor (TLCO)
raised: ⬆asthma, ⬆haemorrhage, ⬆left-to-right shunts, ⬆ polycythaemia
low: everything else - carbon monoxide transfer factor (TLCO)
raised: ⬆asthma, ⬆haemorrhage, ⬆left-to-right shunts, ⬆ polycythaemia
low: everything else
NIV (BiPAP) is indicated in respiratory acidosis or rising PaCO2 resistant to best
medical management during an acute exacerbation of COPD - NIV (BiPAP) is
indicated in respiratory acidosis or rising PaCO2 resistant to best medical
management during an acute exacerbation of COPD
The mainstay of the treatment of allergic bronchopulmonary aspergillosis (ABPA)
is a systemic glucocorticoid such as prednisolone, which is slowly tapered over the
,MRCP 1- Respiratory review 2024
course of 3 to 12 months depending on regimen. - The mainstay of the treatment
of allergic bronchopulmonary aspergillosis (ABPA) is a systemic glucocorticoid such
as prednisolone, which is slowly tapered over the course of 3 to 12 months
depending on regimen.
Asthmatic features/features suggesting steroid responsiveness in COPD:
*previous diagnosis of asthma or atopy
*a higher blood eosinophil count
*substantial variation in FEV1 over time (at least 400 ml)
*substantial diurnal variation in peak expiratory flow (at least 20%) - Asthmatic
features/features suggesting steroid responsiveness in COPD:
*previous diagnosis of asthma or atopy
*a higher blood eosinophil count
*substantial variation in FEV1 over time (at least 400 ml)
*substantial diurnal variation in peak expiratory flow (at least 20%)
Unmasking of Churg-Strauss syndrome: Montelukast - new medication to control
her asthma. Since this has happened, she has developed wrist-drop in her right
, MRCP 1- Respiratory review 2024
arm and foot drop in her left leg = Unmasking of Churg-Strauss syndrome:
Montelukast
Exposure to the following chemicals is associated with occupational asthma:
isocyanates - the most common cause. Example occupations include spray
painting and foam moulding using adhesives
platinum salts
soldering flux resin
glutaraldehyde
flour
epoxy resins
proteolytic enzymes - Exposure to the following chemicals is associated with
occupational asthma:
isocyanates - the most common cause. Example occupations include spray
painting and foam moulding using adhesives
platinum salts
soldering flux resin
glutaraldehyde
COPD: investigation and diagnosis
post-bronchodilator spirometry to demonstrate airflow obstruction: FEV1/FVC
ratio less than 70% - Post-bronchodilator FEV1/FVC < 0.7
FEV1 (of predicted) > 80%
Severity Stage 1 - Mild**
Post-bronchodilator FEV1/FVC < 0.7
FEV1 (of predicted) 50-79%
Severity Stage 2 - Moderate
Post-bronchodilator FEV1/FVC < 0.7
FEV1 (of predicted) 30-49%
Severity Stage 3 - severe
Post-bronchodilator FEV1/FVC < 0.7
FEV1 (of predicted) <30%
Severity Stage4 - very severe
,MRCP 1- Respiratory review 2024
Basal atelectasis should be suspected in the presentation of dyspnoea and
hypoxaemia 72 hours post operatively - Basal atelectasis should be suspected in
the presentation of dyspnoea and hypoxaemia 72 hours post operatively
Isocyanates are the most common cause of occupational asthma - Isocyanates are
the most common cause of occupational asthma
carbon monoxide transfer factor (TLCO)
raised: ⬆asthma, ⬆haemorrhage, ⬆left-to-right shunts, ⬆ polycythaemia
low: everything else - carbon monoxide transfer factor (TLCO)
raised: ⬆asthma, ⬆haemorrhage, ⬆left-to-right shunts, ⬆ polycythaemia
low: everything else
NIV (BiPAP) is indicated in respiratory acidosis or rising PaCO2 resistant to best
medical management during an acute exacerbation of COPD - NIV (BiPAP) is
indicated in respiratory acidosis or rising PaCO2 resistant to best medical
management during an acute exacerbation of COPD
The mainstay of the treatment of allergic bronchopulmonary aspergillosis (ABPA)
is a systemic glucocorticoid such as prednisolone, which is slowly tapered over the
,MRCP 1- Respiratory review 2024
course of 3 to 12 months depending on regimen. - The mainstay of the treatment
of allergic bronchopulmonary aspergillosis (ABPA) is a systemic glucocorticoid such
as prednisolone, which is slowly tapered over the course of 3 to 12 months
depending on regimen.
Asthmatic features/features suggesting steroid responsiveness in COPD:
*previous diagnosis of asthma or atopy
*a higher blood eosinophil count
*substantial variation in FEV1 over time (at least 400 ml)
*substantial diurnal variation in peak expiratory flow (at least 20%) - Asthmatic
features/features suggesting steroid responsiveness in COPD:
*previous diagnosis of asthma or atopy
*a higher blood eosinophil count
*substantial variation in FEV1 over time (at least 400 ml)
*substantial diurnal variation in peak expiratory flow (at least 20%)
Unmasking of Churg-Strauss syndrome: Montelukast - new medication to control
her asthma. Since this has happened, she has developed wrist-drop in her right
, MRCP 1- Respiratory review 2024
arm and foot drop in her left leg = Unmasking of Churg-Strauss syndrome:
Montelukast
Exposure to the following chemicals is associated with occupational asthma:
isocyanates - the most common cause. Example occupations include spray
painting and foam moulding using adhesives
platinum salts
soldering flux resin
glutaraldehyde
flour
epoxy resins
proteolytic enzymes - Exposure to the following chemicals is associated with
occupational asthma:
isocyanates - the most common cause. Example occupations include spray
painting and foam moulding using adhesives
platinum salts
soldering flux resin
glutaraldehyde
