D027 PATHOPHARMACOLOGY EXAM
WITH ALL ANSWERS LATELY
UPDATED
Celiacvdiseasevgoldvstandardv-vcorrectvanswer-Endoscopyvwithvsmallvintestinevbiopsy
advancedvmetastaticvnon-small-cellvlungvcancervgeneticvmutationv-vcorrectvanswer-
EGFRvmutation
20-year-
oldvmalevfallingvfrequently.vSincevchildhood,vhisvgaitvhasvconsistedvofvwalkingvonvhisvtoe
s.vDuringvmiddlevschool,vhevwasvablevtovparticipatevinvsportsvbutvwasvunablevtovparticipa
tevinvhighvschoolvsportsvduevtovdifficultyvwithvrunningvandvjumping.vLately,vhevhasvnotice
dvitvtakesvlongervandvisvmorevdifficultvtovchangevpositionsvfromvsittingvtovstandingvthanvitv
usedvtovinvthevpast.vHevhasvalsovbeenvwakingvupvwithvmusclevandvjointvstiffness.vWhichv
condition?v-vcorrectvanswer-Beckervmuscularvdystrophy
Whichvstatementvshouldvthevprovidervgivevthevpatientvregardingvthevpathophysiologyvofv
SLEvandvitsvrelationvtovthrombocytopenia?v-vcorrectvanswer-
SLEvdisruptsvimmunevhomeostasisvandvpromotesvdevelopmentvofvself-
reactivevantibodies.
elevatedvferritinvlevel.vShevhasvnovpreviousvmedicalvhistoryvandvisvcurrentlyvasymptoma
tic.vShevisvconcernedvaboutvthevelevatedvferritinvandvwouldvlikevtovknowvifvshevshouldvbev
worried.vWhatvshouldvthevprovidervdovnextvforvthisvpatient?v-vcorrectvanswer-
Ordervavlivervfunctionvtest
Av75-year-
oldvfemalevpresentsvtovthevemergencyvdepartmentvwithvanvirregularvheartvratevofv130.vW
hatvcanvbevascertainedvaboutvthisvpatient'svfindingsvgivenvthevlimitedvinformation?v-
vcorrectvanswer-
Shevisvdiagnosedvwithvatrialvfibrillationvandvneedsvhervheartvratevcontrolledvwithvmetopr
ololv(Lopressor).
Whichvconditionvfromvthisvpatient'svmedicalvhistoryvisvcontributingvtovthevlossvofvcontract
ility?v-vcorrectvanswer-Acutevmyocardialvinfarction
, Avtwo-year-
oldvchildvpresentsvwithvavclearvrunnyvnosevandvcoughvwhichvhasvlastedv3vdays.vThevchil
d'svmothervreportsvthevcoughvsoundsvlikevavbarkingvnoise.vThevchildvisvsleepingvinvthevm
other'svarmsvandvappearsvtovhavevstridor.vThevchild'svmothervalsovreportsvanvaxillaryvte
mperaturevofv101°Fvlastvnight.vWhichvmanagementvtechniquevisvappropriatevforvthisvchil
d'svsymptoms?v-vcorrectvanswer-Oralvsteroidsvandvbreathingvtreatments
EDvwithvblurredvvision,vfatigue,vSOB,vdisoriented.vLabs=vglucosev>400,vsodiumv150,vpo
tassiumv7,vserumvbicarbonatev12,vcreatininev3.vWhichvconditionvisvthisvpatientvsufferingv
from?v-vcorrectvanswer-Diabeticvketoacidosis
Av45-year-
oldvfemalevfearsvthatvshevisvhavingvavstrokevandvtakesvherselfvtovanvemergencyvroom.vAf
tervseveralvdiagnosticvandvlaboratoryvtests,vthevpatientvisvdiagnosedvwithvCushingvdisea
se.vWhichvlabvabnormalityvwouldvbevpresentvinvthisvpatient?v-vcorrectvanswer-
Increasedvcortisol
16yovcoughingvandvwheezing,vworsevwithvexercisev-vcorrectvanswer-Asthma
Ptvwithvmemoryvloss,vincontinence,vhallucinations;vsleepinessvandvimpairedvjudgement
.vWhatvlabsvshouldvbevordered?v-vcorrectvanswer-
Completevbloodvcount,vcompletevmetabolicvprofile,vandvurinalysis
Anv18-year-
oldvmalevisvinvolvedvinvavmotorcyclevcrashvwhilevnotvwearingvavhelmet.vHevisvbroughtvint
ovanvemergencyvroomvandvisvimmediatelyvtakenvforvavCTvscan.vThevprovidervtellsvthevpa
tient'svparentsvhevhasvbleedingvbetweenvthevduravmatervandvthevskull.vWhatvisvthisvpatie
nt'svconditionvcalled?v-vcorrectvanswer-Epiduralvhematoma
40yovabdominalvpainvandvdiarrhea-vcolonoscopyvshowsvskipvlesionsv-vcorrectvanswer-
Crohn'svdisease
15yovpainvinvscrotum,vincreasingvsincevmorningvandvnausea.vWhatvtestvshouldvbevorder
ed?v-vcorrectvanswer-Ultrasound
Av45-year-oldvmalevisvbeingvseenvinvthevclinicvforvavyearlyvcheck-
upvandvlabvwork.vHisvhistoryvincludesvhypertensionvandvhyperlipidemiavforvwhichvhevcur
rentlyvtakesvNorvascv5vmgvdailyvandvLipitorv20vmgvnightly.vPatientvhasvavfamilyvhistoryvof
vdiabetes,vhypertension,vheartvdisease,vandvhyperlipidemia.vAftervobtainingvlabvwork,vth
evprovidervnoticesvthevpatient'svhgbA1cvisvelevatedvatv7.5.vThevpatientvisvalreadyvonvavD
ASHvdietvandvwatchingvthevamountvofvsweetsvandvcarbohydratesvheveatsvdaily.vThevpati
entvisvnotvoverweightvandvparticipatesvinvmoderatevphysicalvactivityvatvleastv4-
5vdaysvavweek.vHevwasvstartedvonvMetforminvthreevmonthsvago,vandvhisvhemoglobinvA1
cvisvnowv6.9.vThevnursevexpectsvtovseevavclassvofvmedicationvprescribedvwhichvisvprove
nvtovreducevthevriskvofvcardiovascularvevents.Consideringvthevtreatmentvguidelinesvfro
mvthevAmericanvCollegevofvCardiology,vwhichvmedicationvshouldvbevrecommendedvforvt
hisvpatientv-vcorrectvanswer-Invokanav100vmgvdaily
WITH ALL ANSWERS LATELY
UPDATED
Celiacvdiseasevgoldvstandardv-vcorrectvanswer-Endoscopyvwithvsmallvintestinevbiopsy
advancedvmetastaticvnon-small-cellvlungvcancervgeneticvmutationv-vcorrectvanswer-
EGFRvmutation
20-year-
oldvmalevfallingvfrequently.vSincevchildhood,vhisvgaitvhasvconsistedvofvwalkingvonvhisvtoe
s.vDuringvmiddlevschool,vhevwasvablevtovparticipatevinvsportsvbutvwasvunablevtovparticipa
tevinvhighvschoolvsportsvduevtovdifficultyvwithvrunningvandvjumping.vLately,vhevhasvnotice
dvitvtakesvlongervandvisvmorevdifficultvtovchangevpositionsvfromvsittingvtovstandingvthanvitv
usedvtovinvthevpast.vHevhasvalsovbeenvwakingvupvwithvmusclevandvjointvstiffness.vWhichv
condition?v-vcorrectvanswer-Beckervmuscularvdystrophy
Whichvstatementvshouldvthevprovidervgivevthevpatientvregardingvthevpathophysiologyvofv
SLEvandvitsvrelationvtovthrombocytopenia?v-vcorrectvanswer-
SLEvdisruptsvimmunevhomeostasisvandvpromotesvdevelopmentvofvself-
reactivevantibodies.
elevatedvferritinvlevel.vShevhasvnovpreviousvmedicalvhistoryvandvisvcurrentlyvasymptoma
tic.vShevisvconcernedvaboutvthevelevatedvferritinvandvwouldvlikevtovknowvifvshevshouldvbev
worried.vWhatvshouldvthevprovidervdovnextvforvthisvpatient?v-vcorrectvanswer-
Ordervavlivervfunctionvtest
Av75-year-
oldvfemalevpresentsvtovthevemergencyvdepartmentvwithvanvirregularvheartvratevofv130.vW
hatvcanvbevascertainedvaboutvthisvpatient'svfindingsvgivenvthevlimitedvinformation?v-
vcorrectvanswer-
Shevisvdiagnosedvwithvatrialvfibrillationvandvneedsvhervheartvratevcontrolledvwithvmetopr
ololv(Lopressor).
Whichvconditionvfromvthisvpatient'svmedicalvhistoryvisvcontributingvtovthevlossvofvcontract
ility?v-vcorrectvanswer-Acutevmyocardialvinfarction
, Avtwo-year-
oldvchildvpresentsvwithvavclearvrunnyvnosevandvcoughvwhichvhasvlastedv3vdays.vThevchil
d'svmothervreportsvthevcoughvsoundsvlikevavbarkingvnoise.vThevchildvisvsleepingvinvthevm
other'svarmsvandvappearsvtovhavevstridor.vThevchild'svmothervalsovreportsvanvaxillaryvte
mperaturevofv101°Fvlastvnight.vWhichvmanagementvtechniquevisvappropriatevforvthisvchil
d'svsymptoms?v-vcorrectvanswer-Oralvsteroidsvandvbreathingvtreatments
EDvwithvblurredvvision,vfatigue,vSOB,vdisoriented.vLabs=vglucosev>400,vsodiumv150,vpo
tassiumv7,vserumvbicarbonatev12,vcreatininev3.vWhichvconditionvisvthisvpatientvsufferingv
from?v-vcorrectvanswer-Diabeticvketoacidosis
Av45-year-
oldvfemalevfearsvthatvshevisvhavingvavstrokevandvtakesvherselfvtovanvemergencyvroom.vAf
tervseveralvdiagnosticvandvlaboratoryvtests,vthevpatientvisvdiagnosedvwithvCushingvdisea
se.vWhichvlabvabnormalityvwouldvbevpresentvinvthisvpatient?v-vcorrectvanswer-
Increasedvcortisol
16yovcoughingvandvwheezing,vworsevwithvexercisev-vcorrectvanswer-Asthma
Ptvwithvmemoryvloss,vincontinence,vhallucinations;vsleepinessvandvimpairedvjudgement
.vWhatvlabsvshouldvbevordered?v-vcorrectvanswer-
Completevbloodvcount,vcompletevmetabolicvprofile,vandvurinalysis
Anv18-year-
oldvmalevisvinvolvedvinvavmotorcyclevcrashvwhilevnotvwearingvavhelmet.vHevisvbroughtvint
ovanvemergencyvroomvandvisvimmediatelyvtakenvforvavCTvscan.vThevprovidervtellsvthevpa
tient'svparentsvhevhasvbleedingvbetweenvthevduravmatervandvthevskull.vWhatvisvthisvpatie
nt'svconditionvcalled?v-vcorrectvanswer-Epiduralvhematoma
40yovabdominalvpainvandvdiarrhea-vcolonoscopyvshowsvskipvlesionsv-vcorrectvanswer-
Crohn'svdisease
15yovpainvinvscrotum,vincreasingvsincevmorningvandvnausea.vWhatvtestvshouldvbevorder
ed?v-vcorrectvanswer-Ultrasound
Av45-year-oldvmalevisvbeingvseenvinvthevclinicvforvavyearlyvcheck-
upvandvlabvwork.vHisvhistoryvincludesvhypertensionvandvhyperlipidemiavforvwhichvhevcur
rentlyvtakesvNorvascv5vmgvdailyvandvLipitorv20vmgvnightly.vPatientvhasvavfamilyvhistoryvof
vdiabetes,vhypertension,vheartvdisease,vandvhyperlipidemia.vAftervobtainingvlabvwork,vth
evprovidervnoticesvthevpatient'svhgbA1cvisvelevatedvatv7.5.vThevpatientvisvalreadyvonvavD
ASHvdietvandvwatchingvthevamountvofvsweetsvandvcarbohydratesvheveatsvdaily.vThevpati
entvisvnotvoverweightvandvparticipatesvinvmoderatevphysicalvactivityvatvleastv4-
5vdaysvavweek.vHevwasvstartedvonvMetforminvthreevmonthsvago,vandvhisvhemoglobinvA1
cvisvnowv6.9.vThevnursevexpectsvtovseevavclassvofvmedicationvprescribedvwhichvisvprove
nvtovreducevthevriskvofvcardiovascularvevents.Consideringvthevtreatmentvguidelinesvfro
mvthevAmericanvCollegevofvCardiology,vwhichvmedicationvshouldvbevrecommendedvforvt
hisvpatientv-vcorrectvanswer-Invokanav100vmgvdaily
