21. Musculoskeletal & Anti-Inflammatory Drugs Proven and Reliable Q&A for Top Academic Scores

Musculoskeletal Drugs (2 categories) - Answer 1. Skeletal Muscle Relaxants 2. Nonsteroidal anti-inflammatory drugs (NSAIDs) Skeletal Muscle Relaxants - Answer -classification of drugs that are associated with pain, spasm, abnormal contraction, impaired mobility -short term basis -affect the spinal cord and brain with no direct effect on the skeletal muscle -causes alterations in perception of pain & produces a sedative effect Dantrolene - Answer -type of muscle relaxant that causes a direct effect on the skeletal muscles -manages spasticity (MS or cerebral palsy) -Not for muscle spasms from rheumatic disorders neuromuscular blocking agents (NMBAs) - Answer -used during surgical, endoscopic, or orthopedic procedures -can result in respiratory arrest because of the potential to paralyze major muscle of ventilation, the diaphragm -only administered by anethesiologists Neopstigmine (Prostigmin) - Answer -used as an antidote for NMBAs -used in diagnosis & tx of myasthenia gravis Skeletal Muscle Relaxants (Side Effects) - Answer -Drowsiness, dizziness, dry mouth, weakness, tremor, ataxia, headache, confusion, nervousness, slurred speech, blurred vision, hypotention, GI symptoms, frequency of urination, liver toxicity, respiratory depression Skeletal Muscle Relaxants (Contraindications) - Answer Hypersensitivity to the muscle relaxant, pregnancy, lactation Skeletal Muscle Relaxants (Caution) - Answer Hx of drug abuse, impaired kidney function, liver disorders, blood dyscrasias, COPD, cardiac disord............