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MD3001 Drugs Questions and Correct Answers | Latest Update | A+

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Name two ACE inhibitors. Ans: Ramipril and Lisinopril What is the mechanism of action of Ramipril? Ans: - Inhibits angiotensin conversion enzyme - Prevents the conversion of angiotensin I into angiotensin II - Decreasing the effects of angiotensin II which are; sodium and water retention, vasoconstriction and ADH release. What are the side-effects of Ramipril? Ans: - Persistent Dry Cough - Contra-indicated With Pregnancy - Dizziness - Headaches Name two ARBs. Ans: Lorsartan and Candesartan What is the mechanism of action of an ARB? Ans: - Blocks the angiotensin II receptors - Decreasing the effects of angiotensin II which are; water and sodium retention, vasoconstriction and ADH release. What are the side-effects of ARBs? Ans: - Contra-indicated With Pregnancy - Dizziness - Headaches Name a renin inhibitor. Ans: Aliskiren What is the mechanism of action of Aliskiren? Ans: - Inhibits the release of renin - Interfering with the renin-angiotensin pathway - Decreasing sodium and water retention, vasoconstriction and ADH release. What are the side-effects of Aliskiren? Ans: They are very severe, therefore Aliskiren is rarely used Name three dihydropyridine derivative calcium channel blockers. Ans: Amlodipine, Vercanadipine and Lercanadipine

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