DH206 Pharm Exam Questions With Accurate Answers.
DH206 Pharm Exam Questions With Accurate Answers. QUIZ 1 A drug's generic name is selected by the - answerU.S. Adopted name council Nutritional or herbal supplements - answercan cause adverse effects Each is an advantage of electronic and fax prescribing except one. Which is the exception? - answerThere is no record of the prescription in the patient's record. The word stat on a prescription means - answerimmediately An investigational new drug application (INDA) is submitted _____. - answerbefore phase I trials How are computer and online resources enhancing printed books as a source of information about drugs? (Select all that apply.) - answerTablet computers and smart phones may be used for medication information databases. Some publishers have apps that can be downloaded to smart phones. Which type of drug name usually begins with a lowercase letter? - answergeneric name Two drug formulations that produce similar concentrations in the blood and tissues after drug administration are termed _____ equivalent. - answerbiologically The route of administration of a drug affects both the onset and duration of response. - answerTrue Which is true of a drug with a stronger affinity for a receptor site versus a drug with a weaker affinity for the same site? - answera. A drug with stronger affinity is more potent than a drug with weaker affinity. If a drug is a weak base that is excreted via the kidneys, then acidifying the urine will enhance its excretion. - answerTrue Administering a drug of greater potency is better because drugs of greater potency do not require as high a dose. - answerThe first part of the statement is false; the second part is true. The distribution of a drug is determined by - answerBlood flow to the organ, presence of certain barriers, plasma protein binding capacity, solubility of the drug. All the above One dose of a drug is administered that has a half-life of 8 hours. Assuming first-order kinetics, how much time is needed for this drug to be over 96% eliminated from the body? - answer40 hours A prodrug is an example of which type mechanism of metabolism? - answerinactive, active When different drugs compete for the same receptor sites, the drug with the stronger affinity for the receptor will bind to - answermore receptors than the drug with the weaker affinity If a drug displays zero-order elimination kinetics - answera constant amount is eliminated per unit time. Tetracycline, nonsteroidal antiinflammatory drugs (NSAIDs), and the benzodiazepines are safe to administer to a pregnant patient. - answerFalse In an assessment of drug action for a certain therapeutic agent, results indicate that the ED50 is 3 mg/kg, and the LD50 is 300 mg/kg. What is the therapeutic index for this agent? - answer100 (divide the LD50 value by the ED50 value. The LD50 value (300) divided by the ED50 value (3) equals 100.) A dose of a drug that kills 50% of experimental animals is termed - answerLD50 Drug allergy and a side effect are two examples of dose-related responses. - answerFalse Which is least likely to be a true allergic reaction? - answerdyspepsia Which of the following is the recommended solution for the adverse effect of nausea following administration of a drug? - answerTake the drug with food or milk. An acute, life-threatening allergic reaction characterized by hypotension, bronchospasm, laryngeal edema, and cardiac arrhythmias is what type of hypersensitivity? - answerType I Type _____ hypersensitivity is mediated by IgE antibodies. - answerType I QUIZ 2 Sympathomimetic agents will stimulate salivary flow from which of the following salivary glands: (1) parotid, (2) submandibular, (3) sublingual? - answer2,3 Indications for the use of anticholinergic agents include - answertreatment in combination with levodopa for patients with Parkinson disease Patients pretreated with _____ agents are prone to epinephrine reversal. - answerα-adrenergic blocking A combination of pralidoxime and atropine is used to treat an overdose of _____ inhibitors. - answercholinesterase Neostigmine is an indirect-acting cholinergic agent that is classified as (1) indirect acting and (2) irreversible. - answerClaim 1 is true; claim 2 is false. The action of norepinephrine is terminated by which of the following choices? - answerall of the above Which of the following is a catecholamine? - answerall of the above Which type of autonomic drug is useful to prepare a patient for an ophthalmologic examination? - answerAnticholinergic Agent Sympathomimetic agents should be used with caution in patients with (1) angina, (2) hypertension, (3) hypothyroidism. - answer1,2 Dental pain following a simple tooth extraction is best managed with which of the following choices? - answerIbuprofen 400 mg Which of the following NSAIDs is the drug of choice for treating a nursing woman? - answerIbuprofen Raising the pain threshold increases one's reaction to pain. - answerFalse Febuxostat (Uloric) is used to treat - answerGout Which of the following choices is currently the most popular COX II-specific agent on the market? - answerCelecoxib Pain - answerDoes all of the above Low-dose aspirin therapy is recommended for which of the following? (Select all that apply.) - answerPeople who have had heart bypass surgery, men aged 45-79 with no history of heart disease, and women aged 55-79 with no history of heart disease Which of the following statements is true regarding aspirin and the clotting mechanism? - answerWith lower doses of aspirin, 1 1/2 days should elapse to obtain normal clotting. What is the primary advantage of oxycodone ER over previous formulations? - answerIt is formulated to help deter substance abuse.
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