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  • BIO 245
  • BIO 245
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Tumor markers.

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2023/2024 Written for academic year
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BIO 245
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BIO 245
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Exam of 3 pages for the course BIO 245 at BIO 245 (Tumor markers.)

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Tumor markers
< 20 ng / mL - ANS-AFP Adult levels

2-3 mg / mL - ANS-Fetal serum AFP peaks at 12-15 weeks of gestation with levels of

a - subunit - ANS-common to other hormones

a₁ - antichymotrypsin - ANS-immunologically detectable

a1- Fetoprotein ( AFP ) - ANS-Synthesized in liver , yolk sac , and gastrointestinal ( GI )
tract of fetus

a2 - macroglobulin - ANS-lacks immunoreactivity

B - hCG - ANS-Immunoassay measurement is made of

B - subunit - ANS-unique and not common to other hormones

breast cancer - ANS-Useful for monitoring therapeutic response and for detecting
recurrence of ____________ in patients previously treated

CA 125 - ANS-Marker for ovarian and endometrial cancer

CA 15-3 - ANS-Mucin glycoprotein antigen

CA 19-9 - ANS-Marker for pancreatic , colorectal , lung , and gastric carcinomas

Carcinoembryonic antigen ( CEA ) - ANS-Normally found in epithelial cells of the fetal
GI tract

digestive tract - ANS-Increased levels of CEA are associated with adenocarcinoma of
___________ and colorectal carcinoma .

Enveloped, Complexed, Free PSA, Total PSA - ANS-Forms of PSA found in blood

Enzyme immunoassay - ANS-What AFP methods are used for measurement

Free PSA - ANS-not complexed to protease inhibitor ; immunologically detectable

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